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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | Understanding and Managing the Service Supply Chain 显示文摘 | LISA M ELLRAM WENDY L T COREY B | 2004 | Journal of Supply Chain Management2004，40，4： | 1 |
| 3 | Quantification of deoxynivalenol in wheat using an immunoaffinity column and liquid chromatography显示文摘 | Scott C Kruger Brian T McAlice | 1999 | Journal of Chromatography A1999，859，： | 1 |
| 4 | Pectin induces apoptosis in human prostate cancer cell:correlation of apoptotic function with pectin structure显示文摘 | Crystal L J Tina M D Lisa K T | 2007 | Glyeobiology2007，17，8： | 1 |
| 5 | Orthogonal,convergent syntheses of dendri mers based on melaminewith one or two unique surfacesites for manipulati on显示文摘 | WEN Z DANIELT N LISA M T | 2001 | Journal of the American Chemical Society2001，123，89： | 1 |
| 6 | High-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry and gas chromatography flame ionization detection characterization of △5-polyenoic fatty acids in triacylglycerols from conifer seed oils显示文摘 | Lisa M Holcapek M Rezanka T | 2007 | Journal of Chromatography A2007，1146，1： | 1 |
| 7 | Quantification of deoxynivalenol in wheat using an immunoaffinity column and liquid chromatography显示文摘 | Scott C Kruger Brian T McAlice | 1999 | Journal of Chromatography A1999，859，： | 1 |
| 8 | Understanding and managing the service supply chain显示文摘 | Lisa M Ellram Wendy L T Comy B | 2004 | Journal of Supply Chain Management2004，，： | 1 |
| 9 | Understanding and managing the services supply chain显示文摘 | LISA M E WENDY L T COREY B | 2004 | Journal of Supply Chain Management2004，40，4： | 1 |
| 10 | Spread Spectrum Image Steganography显示文摘 | Lisa M Marvel Charles G Boncelet Charles T Retter | 1999 | IEEE Transactions on Image Processing1999，，8： | 1 |
| 11 | Macrophage-mediated immunostimulation modulates therapeutic efficacy of interleukin-2 based chemoimmunotherapy in advanced metastatic melanoma patients显示文摘 | Bernengo M G Quaglino P Cappello N Lisa F Osella-Abate S Fierro M T | | 0，，01： | 1 |
| 12 | Understanding and Managing the Service Supply Chain显示文摘 | Lisa M Ellram Wendy L T Corey B | 2004 | Journal of Supply Chain Management2004，40，4： | 1 |
| 13 | Femtoscopy in Relativistic Heavy Ion Collisions显示文摘 | Lisa M Prat t S Soltz R | 2005 | Ann Rev Nucl Part Sci2005，55，： | 1 |
| 14 | Qua-ntification of deoxynivalenol in wheat using an immimoaff-inity eolumn and liquid chromatography显示文摘 | Lisa M Cahill Scott C Kruger Brian T McAlice | 1999 | Journal of chr-omatography A1999，859，： | 1 |
| 15 | Understanding and manag- ing the service supply chain 显示文摘 | Lisa M E Wendy I T Corey B | 2004 | Journal of Supply Chain Management2004，40，4： | 1 |
| 16 | Alzheimer's disease markers,hyperten- sion,and gray matter damage in normal elderly显示文摘 | Lidia G Lisa M Wai T | 2012 | Neurobiology of Aging2012，33，7： | 1 |
| 17 | Understanding and managing the services supply chain显示文摘 | Lisa E M Wendy T L Billington Core | 2004 | Journal of Supply Chain Management2004，22，9： | 1 |
| 18 | Biology and therapeutic advances for pediatric osteosarcoma显示文摘 | Neyssa M Mark G Lisa T | 2004 | Oncologist2004，9，4： | 1 |
| 19 | Characterization of an lhxla transgenic reporter in zebrafish显示文摘 | Lisa M S Nobuhiro T Neil A H | 2010 | Int Dev Biol2010，54，： | 1 |
| 20 | Understanding and managing the service supply chain显示文摘 | LISA M E WENDY L T COREY B | 2004 | Journal of Supply Chain Management2004，40，3： | 1 |
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