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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | Metal exposure and Alzheimer's pathogenesis.显示文摘 | Liu G Huang W Moir RD Vanderburg CR Lai B Peng Z Tanzi RE Rogers JT Huang X | 2006 | 中国生物学文摘2006，20，9： | 8 |
| 3 | A new look on wetting models:continuum analysis显示文摘In this study,we considered the wetting phenomenon on a general substrate from a new viewpoint of continuum mechanics.The analyses first show how the Wenzel and the Cassie models deviate the practical results in some special substrates,and then elucidate the mechanism of the triple contact line(TCL) moving.Based upon variational theory of the total free functional dealing with the movable boundary condition,we show that the macroscopic contact angle(MCA) expression is the corresponding transversality condition.It manifests that the MCA depends only on the chemical and geometric property at the TCL,and is not affected by the gravity of the droplet and the contact area beneath the liquid.Our continuum model also shows the exploration of the pinning effect on a sharp wedge or the interface between two different phases.This investigation will help designing super-hydrophobic materials for novel micro-fluidic devices. | LIU JianLin XIA Re ZHOU XiaoHua | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，11： | 4 |
| 4 | A unified analysis of a micro-beam,droplet and CNT ring adhered on a substrate:Calculation of variation with movable boundaries显示文摘In this study, we developed a general method to analytically tackle a kind of movable boundary problem from the viewpoint of energy variation. Having grouped the adhesion of a micro-beam, droplet and carbon nanotube (CNT) ring on a substrate into one framework, we used the developed line of reasoning to investigate the adhesion behaviors of these systems. Based upon the derived governing equations and transversality conditions, explicit solutions involving the critical parameters and morphologies for the three systems are successfully obtained, and then the parameter analogies and common characteristics of them are thoroughly investigated. The presented method has been verified via the concept of energy release rate in fracture mechanics. Our analyses provide a new approach for exploring the mechanism of different systems with similarities as well as for understanding the unity of nature. The analysis results may be beneficial for the design of nano-structured materials, and hold potential for enhancing their mechanical, chemical, optical and electronic properties. | Jian-Lin Liu Re Xia | 2013 | Acta Mechanica Sinica2013，29，1： | 3 |
| 5 | 限制卡路里摄入可抑制大鼠促进动脉衰老的炎症反应,保持年轻的表型显示文摘老化呈指数性增加典型心血管病的发病率和死亡率,这主要是由于动脉壁内分子、细胞和组织水平的动脉促炎变化。动物实验中,大鼠的卡路里限制(calorie restriction,CR)改善了动脉功能并延长了健康跨度和寿命。然而,CR如何影响大鼠动脉壁内分子,细胞和组织表型促炎变化仍有待阐明。该文选取随意喂食的344只年轻(6个月大)和老(24个月大)的Fischer大鼠,获取主动脉;另外选取1组在1个月大时开始只维持40%CR。 | 刘青 叶鹏 Wang MY Zhang L Zhu WQ Zhang J Kim SH Wang YS Ni L Telljohann R Monticone RE McGraw K Liu LJ Rafael de Cabo Lakatta EG | 2018 | 中华高血压杂志2018，26，11： | 3 |
| 6 | 炎症、自身免疫和高血压:组织转谷氨酰胺酶的重要作用显示文摘炎性细胞因子在动物体内可引起高血压。研究表明,细胞因子诱导激活血管紧张素Ⅱ1型受体(angiotensinⅡreceptor type 1,AT1R)的自身抗体的产生,而这些自身抗体,称为AT1-AA,可引发高血压。回顾最近的研究表明,细胞因子诱导型高血压和AT1-AA生成需要一种特定的广泛存在的酶。 | Liu C Kellems RE Xia Y 陈云 叶鹏 | 2018 | 中华高血压杂志2018，26，6： | 3 |
| 7 | hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds显示文摘 | Liu B Parsons RE Hamilton SR | 1994 | Cancer Res1994，54，17： | 2 |
| 8 | Chondrogenic differentiation of mesenchymal stem cells from bone marrow:differentiation-dependent gene expression of matrix components显示文摘 | Barry F Boynton RE Liu B | | 0，，02： | 1 |
| 9 | Salt - as- sisted acid hydrolysis of chitosan to oli- gomers under microwave irradiation 显示文摘 | Xing RE Liu S Yu HH | 2005 | Carbohydrate Research2005，340，13： | 1 |
| 10 | Function of Piwi,a nuclear Piwi/Argonaute protein,is independent of its slicer activity显示文摘 | Darricarrére N Liu N Watanabe T | 2013 | Proc R Soc London Ser A2013，110，4： | 1 |
| 11 | Autonomic nervous system changes in men with chronic pelvic pain syndrome 显示文摘 | YILMAZ U LIU YW BERGER RE | 2007 | J Urol2007，177，6： | 1 |
| 12 | Chondrogenic differentiation of mesenchymal stem cels from bone marrow:differentiation-dependent gene expression of matrix components显示文摘 | Barry F Boynton RE Liu B | | 0，，02： | 1 |
| 13 | Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation dependent gene expression of matrix components显示文摘 | Barry F Boynton RE Liu B | 2001 | Exp Cell Res2001，268，2： | 1 |
| 14 | hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds显示文摘 | Liu B Parsons RE Hamilton SR | 1994 | Cancer Res1994，54，17： | 1 |
| 15 | Nocturnal elevation of intraocular pressure in young adults显示文摘 | Liu JH Kripke DF Hoffman RE | 1998 | Invest Ophthalmol Vis Sci1998，39，13： | 1 |
| 16 | E-Cadherin and Gastric Cancer: Cause, Consequence, and Applications显示文摘 | Xin Liu Kent-Man Chu Valli De Re | 2014 | BioMed Research International2014，，： | 1 |
| 17 | The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development显示文摘 | Wang Y Wan C Deng L Liu X Cao X Gilbert SR Bouxsein ML Faugere M-C Guldberg RE Gerstenfeld LC Haase VH Johnson RS Schipani E Clemens TL | | 0，，： | 1 |
| 18 | Immunohistochemical detection of epithelialmesenchymal transition associated with stemness phenotype in anaplastic thyroid carcinoma显示文摘 | Liu J Brown RE | 2010 | Int J Clin Exp Pathol2010，3，8： | 1 |
| 19 | Assessment of tumor angiogen- esis: dynamic contrast-enhanced MRI with paramagnetic nanoparti- cles compared with Gd-DTPA in a rabbit VX-2 tumor model显示文摘 | Kassner A Thomhill RE Liu F | 2010 | Con- trast media and molecular imaging2010，5，3： | 1 |
| 20 | The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells 显示文摘 | Ramos AD Andersen RE Liu SJ | 2015 | Cell Stem Cell2015，16，4： | 1 |
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