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133篇 您的检索式:作者名="Low H P"
    题名 作者 年代 出处 被引量
1胚胎巨噬细胞和小胶质细胞消融调控小鼠胚胎背根神经节感觉神经元的发育显示文摘众所周知,小胶质细胞可以调节中枢神经系统发育的一些方面。在第11.5天的小鼠胚胎中的小胶质细胞定殖脊髓时,它们与背根神经节感觉神经元(SN)的生长中心轴突相互作用,这表明它们可能在SN发育中发挥一定功能。为了解决这个问题,我们使用缺乏胚胎巨噬细胞(PU.1敲除小鼠)和免疫细胞消融的小鼠胚胎分析胚胎巨噬细胞消融对SNs早期发育的影响。我们发现,除小胶质细胞外,胚胎巨噬细胞还与来自第11.5天的小鼠胚胎的原肌球蛋白受体激酶(Trk)C+感觉神经元,TrkB+感觉神经元和TrkA+感觉神经元外周神经突产生交联。免疫细胞剥夺会导致第11.5天的小鼠胚胎的TrkC+感觉神经元和TrkB+感觉神经元初始数量的减少,这与其发育细胞死亡(DCD)的改变有关联的可能性较小,因为其后在第12.5天的胚胎中的数量有短暂增加。在分析的发育期(第11.5~15.5天),它也导致TrkA+感觉神经元数量减少,尽管我们没有观察到他们的DCD有任何变化。与神经元祖细胞可能存在一致性的脑脂肪酸结合蛋白(BFABP-)阴性细胞的增殖在第11.5天的胚胎中增加,而它们的增殖在第12.5天的胚胎减少,这可部分解释从11.5 d观察到的SN亚型产生的改变。此外,我们观察到在缺乏胚胎巨噬细胞的情况下神经胶质细胞祖细胞(BFABP+细胞)增殖的改变。我们的数据表明,胚胎巨噬细胞和小胶质细胞消融调控SN的发育。Angelim MKSC Maia LMSS Mouffle C Ginhoux F Low D Amancio-Dos-Santos A Makhoul J Le Corronc H Mangin JM Legendre P 聂昊(编译) 2018神经损伤与功能重建2018,13,9:2
2On the reconfiguration of de- gradable VLSI/WSI arrays显示文摘Low C P Leong H W 1997IEEE Trans Comput- er-Aided Design of Integrated Circuits and Systems1997,16,10:1
3Anti-diabetic effects of Cichorium intybus in streptozotocin-induced diabetic rats 显示文摘Pushparaj P N Low H K Manikandan J 2007J Ethnopharmaeol2007,111,2:1
4Preparation of mixed-matrix membranes for micellar enhanced ultrafiltration based on response surface methodology显示文摘Ngang H P Ahmad A L Low S C 2012Desalination2012,293,:1
5In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes 显示文摘Lachmann H J Lowe P Felix SD 2009J Exp Med2009,206,:1
6Analysis of food oligosaccharides using MALDI-MS:quantification of fructooligosaccharides显示文摘WANG J SPORNS P LOW N H 1999Journal of Agricultural and Food Chemistry1999,47,4:1
7A Retrospective Evaluation of Operative Treatment of Ankle Fractures显示文摘Low C K Pang H Y Wong H P 1997Ann Acad Med Singapore1997,26,:1
8Internationalization of Chinese construction enterprises 显示文摘Low S P Jiang H B 2003Journal of Construction Engineering and Management2003,129,6:1
9Regulation of Ras signal transduction in normal and transformed cell 显示文摘Lowe P N Skinner R H 1994Cell Signaling1994,6,2:1
10Discrimination between transmissible gastroenteritis virus isolates 显示文摘Lowings P Lauds H Cbarley B 1997Archives of Virology1997,142,8:1
11The roles of oxidative stress and antioxidant treatment In experimental diabetic neuropathy显示文摘Low P A Nickander K K Tritschler H J 1997Diabetes1997,3,2:1
12Significance of the lateral epiphysis of the acetabulum to hip joint stability显示文摘Singh S Hee H T Low V P 0,,02:1
13An efficient and robust numerical scheme for SIMPLER algorithm on non-orthogonal curvilinear coordinates, CLEARER 显示文摘Cheng Y P Lee T S Low H T 2007Numerical Heat Transfer Part B2007,51,:1
14Preparation of Ag2S nanocrystals of predictable shape and size 显示文摘Lim W P Zhang Z H Low H Y 2004Angewandte Chemic International Edition2004,43,42:1
15Poiseuille flow to measure the viscosity of particle model fluids 显示文摘BACKER J A LOWE C P HOEFSLOOT H C J 2005The Journal of Chemical Physics2005,122,15:1
16Abnormal glucose metabolism and pancreatic cancer mortality显示文摘GAPSTUR S M GANN P H LOWE W 2000JA- MA2000,283,19:1
17Purification of a glycoprotein elicitor phytoalexin formation from Verticillium dahliae显示文摘DAVIS D A Low P S H einstein P 1998Physiol Mol Plant Pathol1998,52,:1
18A Career Stage Perspective on Employees Preferred Psychological Contract Contributions and Inducements 显示文摘LOW C H BORDIA P 2011Journal of Management and Organization2011,17,6:1
19Antidiabetic effects of Cichorium lntybus in streptozotocininduced diabrtic rats显示文摘Pushparaj P N Low H K Manikandan J 2007J Ethnopharmacol2007,111,2:1
20IR-lumincscont PbS-polystyrene nanocomposites prepared from random ionomers in solution显示文摘Lim W P Low H Y Chin W S 2004Journal of Physical Chemstry B2004,108,13:1
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