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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Posttreatment of a brewery wastewater using a sequencing batch reactor 显示文摘 | Rordrigues Ana C Brito Antonio G Melo Luis F | 2001 | Water Environment Research2001，73，1： | 2 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Retrieval of oceanic chlorophyll concentration with relevance vector maehines 显示文摘 | Gustavo C Luis G Jordi M | 2006 | Remote Sens Environ2006，105，1： | 1 |
| 5 | Analysis of three tissue-specific elements from the wheat Cab-1 enhancer显示文摘 | Cecillia G Luis C R Keiko I | 1993 | The Plant Journal1993，3，： | 1 |
| 6 | Scale invariance in the nonstationarity of human heart rate 显示文摘 | Pedro B G Plamen C I Luis A N et aI | 2001 | Physical Review Letters2001，87，16： | 1 |
| 7 | Inhibition effects of nitrogen compounds on the hydrodesulfurization of dibenzothiophene显示文摘 | LAREDO S G C DE LOS REYES H J A LUIS CANO D J | 2001 | Applied Catalysis2001，207，12： | 1 |
| 8 | A review of volatile analytical methods for determining the botanical origin of honey 显示文摘 | Luis F C G Jorge A P Louis S S | 2007 | Food Chem2007，103，： | 1 |
| 9 | Collabora- tive networked organizations--concepts and practice in manu- facturing enterprises显示文摘 | LUIS M C HAMIDEH A NATHALIE G | 2009 | Computers Industrial Engineer- ing2009，57，1： | 1 |
| 10 | Peanut Shell Acti- vated carbon: adsorption capacities for Copper ( II ), Zinc ( II ), Nickel( II ) and Chromium(VI) ions from aqueous solutions显示文摘 | LUIS C R ANTONIO B ELIO E G | 2004 | Adsorption Science and Technol- ogy2004，22，3： | 1 |
| 11 | Acid-activated carbons from peanut shells: synthesis, characterizat ion and uptake of organic compound from aqueous solutions显示文摘 | Luis C R Antonio B Elio E G | 2003 | Adsorption Science and Technology2003，21，7： | 1 |
| 12 | Dynamic Buckling of Anchored Steel Tanks Subjected to Horizontal Earthquake Excitation 显示文摘 | Juan C V Luis A G Luis E S | 2006 | Journal of Constructional Steel Research2006，62，6： | 1 |
| 13 | A validated solid - liquid extraction method for the HPLC determination of polyphenols in apple tissues Comparison with pressurised liquid extraction显示文摘 | ROSA M ALEJANDRO B EDURNE C LUIS A BLANCA G FRANCISCA V | 2005 | Talanta2005，，65： | 1 |
| 14 | ISSR analysis of cultivars of pearand suitability of molecular markers for clone discrimination 显示文摘 | Luisa M C Luis G Cristina O | 2001 | Journal of the American Society for Horticultural Science2001，126，5： | 1 |
| 15 | Adherence pili of pathogenic srains of avian Escherichia coli显示文摘 | Helio R N Marilda C V Luis C J G | 1997 | Veterinary Microbiology1997，59，： | 1 |
| 16 | Epicuticular wax content and mor- phology as related to ethylene and storage performance of 'Navelate~ orange fruit显示文摘 | Jacques F C Luis G C Ana V | 2010 | Postharvest Biology and Technology2010，55，： | 1 |
| 17 | A review of volatile ana- lytical methods for determining the botanical origin of honey 显示文摘 | Luis F C G Jorge A P Louis S S | 2007 | Food Chemistry2007，103，： | 1 |
| 18 | Tumor angiogenesis and p53 protein expression in mammary phyllodes tumors显示文摘 | Tse G M K Lui P C Scolyer R A | 2003 | Mod Pathol2003，16，10： | 1 |
| 19 | Removal of or-ganic matter and nutrients from urban wastewater by using anexperimental emergent aquatic macrophyte system显示文摘 | ANSOLA G FERNANDEZ C DE LUIS E | 1995 | Eco-logical Engineering1995，5，1： | 1 |
| 20 | An efficient controller for an adjustable speed induction-motor drive显示文摘 | GARCIA G O LUIS J C STEPHAN R M | 1994 | IEEE Transactions on Industrial Electronics1994，41，5： | 1 |
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