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| 1 | 危险度评价最新进展显示文摘在过去的几十年里 ,人们开发了许多新的方法来改进化学品危险度评价中的剂量 反应关系的评定 :如采用定义较为完善的有效作用剂量来替代无可见有害作用水平(NOAEL) ,以及改进了的不确定 /安全系数的评定方法。本文将介绍目前国际上使用较为广泛的几种评定方法 :①采用剂量 反应关系数学模拟的方法来估计有效剂量以取代NOAEL作为安全剂量的出发起点值的剂量 反应关系的评定方法 ,包括 :“基准剂量法”和“分类回归法” ;②使用种系内和种系间毒代动力学和毒效动力学的资料来选择不确定系数的“基于数据的不确定系数法” ;③用于估计不确定系数的可信区间 ,以及计算安全剂量值的可信区间的“概率参考剂量法”。 | 赵启宇 阚海东 Lynne HABER 陈秉衡 Michael DOURSON | 2004 | 中国药理学与毒理学杂志2004，18，2： | 15 |
| 2 | The prevalence of limited health literacy显示文摘 | Michael K. Paasche-Orlow Ruth M. Parker Julie A. Gazmararian Lynn T. Nielsen-Bohlman Rima R. Rudd | 2005 | Journal of General Internal Medicine2005，，2： | 3 |
| 3 | 重塑能源-中国:能效在中国面向2050年路线图中的作用显示文摘作为《巴黎协定》承诺的一部分,中国计划在2030年左右达到二氧化碳(CO_2)排放峰值并争取尽早达峰。在研究如何实现上述减排承诺的前提下,中美研究人员组成的团队构建了一个自下而上的中国能源供需综合模型。基于该模型对比分析了两种情景的差异,即沿着当前趋势发展的参考路径情景以及'重塑能源'替代路径情景。'重塑能源'替代路径是指为满足国家需求,在2050年前最大程度地应用当前成本有效的能源效率策略和可再生能源。结果表明,如果中国走更积极的重塑能源路径,那么其二氧化碳排放量可比参考路径提前11年达峰。本文重点分析了在更积极的路径下能源效率策略对于二氧化碳减排的作用。除能源效率外,本研究还分析了燃料替换(从碳密集型燃料转向其他燃料)的减排作用。结果表明,对于重塑能源情景,能源效率提高及相关策略贡献了中国2050年二氧化碳总减排潜力的75%,而燃料替换仅占25%。为在中国实现上述具有显著成本效益的能效潜力。 | Lynn Price Nina Khanna Nan Zhou David Fridley Ali Hasanbeigi Hongyou Lu Feng Wei 戴彦德 田智宇 杨宏伟 白泉 朱跃中 熊华文 张建国 Jon Creyts Kate Chrisman Ellen Franconi Josh Agenbroad Michael Bendewald Yi Ke Robert McIntosh David Mullaney Clay Stranger Daniel Wetzel Cvrd Yee | 2018 | 科学与管理2018，38，3： | 3 |
| 4 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015，21，18： | 2 |
| 5 | Hemoglobin Level, Chronic Kidney Disease, and the Risks of Death and Hospitalization in Adults With Chronic Heart Failure: The Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study显示文摘 | Alan S. Go Jingrong Yang Lynn M. Ackerson Krista Lepper Sean Robbins Barry M. Massie Michael G. Shlipak | 2006 | Circulation2006，，23： | 2 |
| 6 | Kidney Damage and Renal Functional Changes are Minimized by Waveform Control that Suppresses Cavitation in Shock Wave Lithotripsy显示文摘 | Andrew P. Evan Lynn R. Willis James A. McAteer Michael R. Bailey Bret A. Connors Youzhi Shao James E. Lingeman James C. Williams Naomi S. Fineberg Lawrence A. Crum | 2002 | The Journal of Urology2002，，4： | 2 |
| 7 | Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes显示文摘 | Ding-Wu Shen Lynn M. Pouliot Matthew D. Hall Michael M. Gottesman | 2012 | Pharmacological Reviews2012，，3： | 2 |
| 8 | A systematic review of multidisciplinary outcomes in themanagement of chronic low back pain显示文摘 | Lynn Shaw Birgit Prodinger Karen Jacobs Michael J. Ravenek Ian D. Hughes Nathan Ivanovich Kevin Tyrer Christopher Desrochers Lisa Klinger Lynn Shaw | 2009 | Work2009，，3： | 2 |
| 9 | Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure显示文摘 | Daniel E. Forman Javed Butler Yongfei Wang William T. Abraham Christopher M. O’Connor Stephen S. Gottlieb Evan Loh Barry M. Massie Michael W. Rich Lynne Warner Stevenson James B. Young Harlan M. Krumholz | 2004 | Journal of the American College of Cardiology2004，，1： | 2 |
| 10 | Early Goal-Directed Sedation Versus Standard Sedation in Mechanically Ventilated Critically Ill Patients: A Pilot Study*显示文摘 | Yahya Shehabi Rinaldo Bellomo Michael C. Reade Michael Bailey Frances Bass Belinda Howe Colin McArthur Lynne Murray Ian M. Seppelt Steve Webb Leonie Weisbrodt | 2013 | Critical Care Medicine2013，，： | 2 |
| 11 | α核素用于放射治疗:从基础放射化学到临床研究(第二部分)显示文摘利用放射源将具有细胞毒性的电离辐射作用到病灶处的方法可以追溯到20世纪初,起源于镭的发现及其能够产生的生理作用。α核素在放射治疗应用于临床肿瘤学领域中备受关注。该综述的第一部分探讨了基本的放射化学、高细胞杀伤效力和α核素的可应用性,以及存在于放射性标记方法和子核再分布的阻碍。该综述的第二部分将概述α核素在临床前和临床研究中最有希望和最新的用途。 | Sophie Poty Lynn C.Francesconi Michael R.McDevitt Michael J.Morris Jason S.Lewis 杨晖 关志伟(译) 徐白萱(审校) | 2020 | 中华核医学与分子影像杂志2020，40，12： | 2 |
| 12 | Magnetic resonance studies of jets in a gas-solid fluidised bed显示文摘Magnetic resonance imaging (MRI) has been used to study the behaviour of jets at the distributor of a 50 mm diameter fluidised bed of 0.5 mm diameter poppy seeds. Two perforated-plate distributors were examined, containing either 10 or 14 holes, each 1 mm diameter. Ultra-fast MR imaging was able to show the transient nature of the upper parts of the jets, where discrete bubbles are formed. Imaging in 3D showed that the central jets were the longest for flow rates below minimum fluidisation. Above minimum fluidisation, the outer jets, nearest the wall of the fluidised bed, arched inward towards the central axis. In this latter case, interpretation of the time-averaged 3D image required the use of ultra-fast MR imaging to identify the approximate height above the distributor at which discrete bubbles were formed. The apparently continuous void extending along the central axis above this height in the time-averaged 3D image was thus identified, using ultra-fast MR imaging, as representing the averaged paths of released bubbles. Time-averaged MR velocity mapping was also used to identify dead zones of stationary particles resting on the distributor between the jets. The dead zones could be observed when the superficial velocity of the gas approached minimum fluidisation, but they were smaller than those observed at lower gas superficial velocity. Comparable images of a single jet through 1.2 mm diameter poppy seeds from MRI and electrical capacitance volume tomography (ECVT) are also demonstrated. | Meenal Pore Thusara C. Chandrasekera Daniel J. Holland Aining Wang Fei Wang Qussai Marashdeh Michael D. Mantle Andrew J. Sederman Liang-Shih Fan Lynn F. Gladden John S. Dennis | 2012 | Particuology2012，10，2： | 2 |
| 13 | The plausibility of micronutrient deficiencies being a significant contributing factor to the occurrence of pregnancy complications 显示文摘 | Carl L K Michael S C Lynn A H | 2003 | J Nutr2003，133，： | 1 |
| 14 | Long-term Risk of Glaucoma After Congenital Cataract Surgery显示文摘 | Scott R. Lambert Amitabh Purohit Hillary M. Superak Michael J. Lynn Allen D. Beck | 2013 | American Journal of Ophthalmology2013，，2： | 1 |
| 15 | Scarcity’s Enhancement of Desirability: The Role of Naive Economic Theories显示文摘 | Michael Lynn | 1992 | Basic and Applied Social Psychology1992，，1： | 1 |
| 16 | A framework for evaluating the customer wait experience显示文摘 | Kelly A. McGuire Sheryl E. Kimes Michael Lynn Madeline E. Pullman Russell C. Lloyd | 2010 | Journal of Service Management2010，，3： | 1 |
| 17 | The prevalence of limited health literacy显示文摘 | Dr. Michael K. Paasche-Orlow MD MPH Ruth M. Parker MD Julie A. Gazmararian MPH PhD Lynn T. Nielsen-Bohlman PhD Rima R. Rudd ScD | 2005 | Journal of General Internal Medicine2005，，2： | 1 |
| 18 | Using rbcL sequence data to reassess the taxonomic position of some Grateloupia and Dermocorynus species (Halymeniaceae, Rhodophyta) from the north-eastern Atlantic显示文摘 | Robert J. Wilkes Lynne M. McIvor Michael D. Guiry | 2005 | European Journal of Phycology2005，，1： | 1 |
| 19 | Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients显示文摘 | Judith Jacobi Nicholas Bircher James Krinsley Michael Agus Susan S. Braithwaite Clifford Deutschman Amado X. Freire Douglas Geehan Benjamin Kohl Stanley A. Nasraway Mark Rigby Karen Sands Lynn Schallom Beth Taylor Guillermo Umpierrez John Mazuski Holger S | 2012 | Critical Care Medicine2012，，12： | 1 |
| 20 | Presentation and outcome of hepatocellular carcinoma in HIV-infected patients: A U.S.–Canadian multicenter study显示文摘 | Norbert Br?u Rena K. Fox Peiying Xiao Kristen Marks Zeenat Naqvi Lynn E. Taylor Anita Trikha Morris Sherman Mark S. Sulkowski Douglas T. Dieterich Michael O. Rigsby Teresa L. Wright Maria D. Hernandez Mamta K. Jain Gajendra K. Khatri Richard K. Sterling M | 2007 | Journal of Hepatology2007，，4： | 1 |
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