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| 1 | TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation显示文摘Transforming growth factor-beta(TGF-β)/bone morphogenetic protein(BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases. Perturbations of TGF-β/BMP activity are almost invariably linked to a wide variety of clinical outcomes, i.e., skeletal, extra skeletal anomalies, autoimmune, cancer, and cardiovascular diseases. Phosphorylation of TGF-β(I/II) or BMP receptors activates intracellular downstream Smads, the transducer of TGF-β/BMP signals. This signaling is modulated by various factors and pathways, including transcription factor Runx2. The signaling network in skeletal development and bone formation is overwhelmingly complex and highly time and space specific.Additive, positive, negative, or synergistic effects are observed when TGF-β/BMP interacts with the pathways of MAPK, Wnt, Hedgehog(Hh), Notch, Akt/m TOR, and mi RNA to regulate the effects of BMP-induced signaling in bone dynamics. Accumulating evidence indicates that Runx2 is the key integrator, whereas Hh is a possible modulator, mi RNAs are regulators, and b-catenin is a mediator/regulator within the extensive intracellular network. This review focuses on the activation of BMP signaling and interaction with other regulatory components and pathways highlighting the molecular mechanisms regarding TGF-β/BMP function and regulation that could allow understanding the complexity of bone tissue dynamics. | Md Shaifur Rahman Naznin Akhtar Hossen Mohammad Jamil Rajat Suvra Banik Sikder M Asaduzzaman | 2015 | Bone Research2015,3,1: | 53 |
| 2 | Managing realtime database transactions in mobile ad-hoc networks显示文摘 | Le Gruenwald Shankar M Banik Chuo N Lau | 2007 | Distributed and Parallel Database2007,22,1: | 1 |
| 3 | Effect of pre-and postharvest treatments with calcium compounds on the incidence of postharvest fruit rots of mango显示文摘 | Kaiser S A K M Dhua R S Banik A K | 2001 | Journal of Mycopathological Research2001,39,: | 1 |
| 4 | Nanoclay modified water-blown polyurethane foams derived from bifunctional soybean oil-based polyol显示文摘 | BANIK I SAIN M M | 2010 | Polymer-Plastics Technology and Engineering2010,49,7: | 1 |
| 5 | Reexamination of the difference in susceptibility to adjuvant-induced arthritis among LEW/Crj, Sic/Wistar/ST and Sic/SD rats显示文摘 | Banik R K Kasai M Mizumura K | 2002 | Exp Anita2002,51,2: | 1 |
| 6 | Opti- mization of nutrients for gellan gum production by Sphin- gomonas paucimobilis ATCC 31461 in molasses based medium using response surface methodology 显示文摘 | BANIK R M SANTHIAGU A UPADHYAY S N | 2007 | Biore- sour Technol2007,98,4: | 1 |
| 7 | A remarkable iodine-catalyzed protection of carbonyl compounds显示文摘 | Banik B K Chapa M Marquez J | 2005 | Tetrahedron Lett2005,46,: | 1 |
| 8 | Purification and Characterization of Bacillus cereus Protease Suitable for Detergent lndtrstW显示文摘 | PRAKASH M BANIK R M KOCH-BRANDT C | 2005 | Applied Biochemistry and Biotechnology2005,127,: | 1 |
| 9 | Polysaccharide hydrolases in germinated barley and their role in the depolymerization of plant and fungal cell walls显示文摘 | Hrmova M Banik M Harvey A J | 1997 | International Journal of Biological Macromolecules1997,21,1: | 1 |
| 10 | Inhibition of proprotein convertases-1 ,- 7 and furin by diterpines of Andrographis paniculata and their succinoyl esters显示文摘 | Basak A Cooper S Roberge A G Banik U K Chretien M Seidah N G | 1999 | Biochem J1999,338,1: | 1 |
| 11 | Exopolysaccharide of the gellan family:prospects and potential 显示文摘 | Banik R M Kanari B Upadhyay S N | 2000 | World Journal of Microjbiology and B iotechnology2000,16,5: | 1 |
| 12 | Human arteries engineered in vitro显示文摘 | BOYER M J MCKEE J A BANIK S S | 2003 | EMBO Rep2003,4,6: | 1 |
| 13 | Studies on the efficacy of a phytohormone producing pliospliate solubiliz-ing Bacillus subtilis in augmenting paddy yield in acid soils of N-agaland显示文摘 | Gupta R K Datta M Banik S | 2000 | Plant and Soil2000,89,: | 1 |
| 14 | Identification of Armillaria species from Wisconsin and adjadent areas 显示文摘 | Banik M T Paul J A Burdsall H H | 1995 | Mycologia1995,87,: | 1 |
| 15 | An Image Encryption Process based on Chaotic Logistic Map显示文摘 | Mandal M K Banik G D Chattopadhyay D | 2012 | IETE Technical Review2012,29,5: | 1 |
| 16 | An Image Eneryption Process based on Chaotic Logistic Map显示文摘 | MANDAL M K BANIK G D CHATrOPADHYA'Y D | 2012 | IETE Technical Review2012,,29: | 1 |
| 17 | Armillaria nabsnona, a new species from western North America显示文摘 | Volk T J Burdsall H H Banik M T | 1996 | Mycologia1996,88,: | 1 |
| 18 | Serf assembly of silver( I ) complexes containing 1,4-Bis benzene 显示文摘 | Tzeng B C Banik M Selvam T S | 2013 | Cryst Growth Des2013,13,10: | 1 |
| 19 | Thermoelastic interaction with energy dissipation in an infinite solid with distributed periodically varying heat sources显示文摘 | Banik S Mallik S H Kanoria M | 2007 | Int JPure Appl Math2007,34,2: | 1 |
| 20 | Fine needle aspiration cy-tology of malignant endovascular papillary angioendothelioma显示文摘 | Banik T Sinha A K Rai M K ef al | 2011 | Diagn Cytopathol2011,39,7: | 1 |