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| 1 | “猪地方性肺炎及其防治控制”专栏二:有关猪肺炎支原体感染诊断方法和流行病学的最新观点显示文摘猪肺炎支原体是猪地方性肺炎(Enzoodc Pneumonia,EP)的主要病原体,本病是一种主要影响肥育猪的慢性呼吸道疾病。尽管人们在控制猪肺炎支原体感染及其带来的不利影响上花费了大量的精力,但是猪地方性肺炎仍继续给全球养猪生产造成重大的经济损失。猪肺炎支原体通常是通过引进亚临床型感染的动物而侵入猪群的,或通过短距离的空气传播发生感染,但后一种情况较少。一旦侵入猪群,猪肺炎支原体可通过与受感染的母猪直接接触而将病原体传给后代或在同圈猪只之间进行传播。用于诊断猪肺炎支原体感染的“黄金标准”技术——细菌学培养非常费劲,通常很少使用。酶联免疫吸附试验和聚合酶链式反应检测方法以及以屠宰场监测或田间剖解为形式的死后检查,是用于调查猪肺炎支原体是否参与了猪呼吸道疾病的最常用技术。这些技术已被用来监测受猪地方性肺炎影响的猪群猪肺炎支原体的临床型和亚临床型感染猪群、免疫猪群或非免疫猪群以及处于不同的生产条件和管理奈件下的猪群的发生情况。猪场水平上的猪地方性肺炎临床过程差异以及猪肺炎支原体疫苗接种效果的差异表明,猪肺炎支原体的不同田间分离株的传播和毒力特性存在差异。本文综述了猪肺炎支原体感染的流行病学最新知识,包括其传播、感染和血清转化动力学,并且还比较了用来监测猪地方性肺炎的各种流行病学方法。 | Marina Sibila Maria Pieters Thomas Molitor Dominiek Maes Freddy Haesebmuck Joaquim Segal e s 沈权(译) 邵嘉佳(校) | 2009 | 国外畜牧学(猪与禽)2009，，3： | 16 |
| 2 | Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome显示文摘Polycystic ovary syndrome(PCOS) is the most common endocrine disorder in reproductive-aged women. Women with PCOS frequently have metabolic complications including insulin resistance(IR), early diabetes, hypertension and dyslipidemia. Recent studies have demonstrated an association between PCOS and another metabolic complication: nonalcoholic fatty liver disease(NAFLD). NAFLD occurs as a result of abnormal lipid handling by the liver, which sensitizes the liver to injury and inflammation. It can progress to nonalcoholic steatohepatitis(NASH), which is characterized by hepatocyte injury and apoptosis. With time and further inflammation, NASH can progress to cirrhosis. Thus, given the young age at which NAFLD may occur in PCOS, these women may be at significant risk for progressive hepatic injury over the course of their lives. Many potential links between PCOS and NAFLD have been proposed, most notably IR and hyperandrogenemia. Further studies are needed to clarify the association between PCOS and NAFLD. In the interim, clinicians should be aware of this connection and consider screening for NAFLD in PCOS patients who have other metabolic risk factors. The optimal method of screening is unknown. However, measuring alanine aminotransferase and/or obtaining ultrasound on high-risk patients can be considered. First line treatment consists of lifestyle interventions and weight loss, with possible pharmacologic interventions in some cases. | Carly E Kelley Ann J Brown Anna Mae Diehl Tracy L Setji | 2014 | World Journal of Gastroenterology2014，20，39： | 11 |
| 3 | Increased plasma concentrations of interleukin-6,soluble interleukin-6,soluble interleukin-2 and transferring receptor in major depression显示文摘 | Maes M Mehzer H Bosmans E | 1995 | J Affect Disord1995，34，4： | 1 |
| 4 | Influence of the Pt electrode on the properties of sol-gel PZT-films显示文摘 | Willems G J Wouters D J Maes H E | 1995 | Microelectronic Engineering1995，29，14： | 1 |
| 5 | In vivo immunomodulatory effects of clozapine in schizophrenia显示文摘 | Maes M Bosmans E Kenis G | 1997 | Schizo Res1997，26，： | 1 |
| 6 | Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts显示文摘 | Maes OC Sarojini H Wang E | 2009 | J Cell Physiol2009，221，1： | 1 |
| 7 | High genetic diversity and connectivity in a common mesopelagic fish of the Southern Ocean:the myctophid Electrona antarctica显示文摘 | Van De Putte A P Van Houdt J K J Maes G E | 2011 | Deep Sea Research Part II:Topical Studies in Oceanography2011，5960，： | 1 |
| 8 | On the Governance of In- formation: Introducing a New Concept of Governance to Support the Management of Information 显示文摘 | Kooper M N Maes R Lindgreen E R | 2010 | International Journal of In- formation Management2010，31，5： | 1 |
| 9 | The new‘5-HT'hypothesis of depression:cell-mediated immune activation induces indoleamine 2,3-dioxygenase,which leads to loweR plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs),both of which contribute to the onset of depression显示文摘 | Maes M Leonard B E Myint A M | 2011 | Prog Neuropsychopharmacol Biol Psychiatry2011，35，3： | 1 |
| 10 | Increased scrum inter Leu-kin -1 receptor - antagonist concentrations in major depression 显示文摘 | Maes M Vandoolaeghe E Ranjan R | 1995 | J Affect Disord1995，36，12： | 1 |
| 11 | The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma显示文摘 | Maes K De Smedt E Lemaire M | 2014 | Oncotarget2014，32，12： | 1 |
| 12 | Inter- leukin - 2 and interleukin - 6 in schizophrenia and mania: Effects of neuroleptics and mood stabilizers显示文摘 | Maes M Bosmans E Cadobrese J | 1995 | Paychiatry Res1995，29，： | 1 |
| 13 | A reliable approach to charge-pumping measurements in MOS transistors 显示文摘 | GROESENEKEN G MAES H E BELTRAN N et at | 1984 | 1EEE Trans Elec Dev1984，31，1： | 1 |
| 14 | Hypoxia-driven pathways in bone development,regeneration and disease显示文摘 | Maes C Carmeliet G Schipani E | | 0，，： | 1 |
| 15 | Comparison of acute inflammatory and chronic structural asthma-like responses between C57BL/6and BALB/c mice显示文摘 | Van Hove CL Maes T Cataldo DD Gueders MM Palmans E Joos GF | | 0，，： | 1 |
| 16 | A viscous fluid model for muhimodal non - rigid image registration using mutual in- formation显示文摘 | D'Agostino E Maes F Vandermeulen D | 2003 | Medical Image Analysis2003，7，4： | 1 |
| 17 | Increased serum interleukin-1receptor antagonist concentrations in major depression显示文摘 | Maes M Vandoolaeghe E Ranjan R | 1995 | J Affect Disord1995，36，12： | 1 |
| 18 | Hypoxia-driven pathways in bone development,regeneration and disease显示文摘 | Maes C Carmeliet G Schipani E | 2012 | Nat Rev Rheumatol2012，，8： | 1 |
| 19 | Fixation of radiocaesium traces in a weathering sequence mica-vermiculite-hydroxy interlayered vermiculite显示文摘 | Vielvoye L Stone W | 1999 | European Journal of Soil Science1999，50，2： | 1 |
| 20 | Increased plasma concentrations of interleukin-6,soluble interleukin-6 receptor,soluble interleukin-2 receptor and transferrin receptor in major depression显示文摘 | Maes M Meltzer H Bosmans E | 1995 | J Affect Disord1995，34，4： | 1 |
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