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| 1 | Predictors of All-Cause Mortality and Liver-Related Mortality in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD)显示文摘 | Maria Stepanova Nila Rafiq Hala Makhlouf Ritambhara Agrawal Ishmeet Kaur Zahra Younoszai Arthur McCullough Zachary Goodman Zobair M. Younossi | 2013 | Digestive Diseases and Sciences2013，，10： | 4 |
| 2 | Barrett's esophagus:Prevalence and risk factors in patients with chronic GERD in Upper Egypt显示文摘AIM:To determine the prevalence and possible risk factors of Barrett's esophagus(BE) in patients with chronic gastroesophageal reflux disease(GERD) in El Minya and Assuit, Upper Egypt.METHODS:One thousand consecutive patients with chronic GERD symptoms were included in the study over 2 years.They were subjected to history taking including a questionnaire for GERD symptoms, clinical examination and upper digestive tract endoscopy.Endoscopic signs suggestive of columnar-lined esophagus(CLE) were defined as mucosal tongues or an upward shift of the squamocolumnar junction.BE was diagnosed by pathological examination when specialized intestinal metaplasia was detected histologically in suspected CLE.pH was monitored in 40 patients.RESULTS:BE was present in 7.3% of patients with chronic GERD symptoms, with a mean age of 48.3 ± 8.2 years, which was signif icantly higher than patients with GERD without BE(37.4 ± 13.6 years).Adenocarcinomawas detected in eight cases(0.8%), six of them in BE patients.There was no signiflcant difference between patients with BE and GERD regarding sex, smoking, alcohol consumption or symptoms of GERD.Patients with BE had significantly longer esophageal acid exposure time in the supine position, measured by pH monitoring.CONCLUSION:The prevalence of BE in patients with GERD who were referred for endoscopy was 7.3%.BE seems to be associated with older age and more in patients with nocturnal gastroesophageal reflux. | Yasser M Fouad Madiha M Makhlouf Heba M Tawfik Hussein El Amin Wael Abdel Ghany Hisham R El-khayat | 2009 | World Journal of Gastroenterology2009，15，28： | 4 |
| 3 | Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD显示文摘AIM: To detect a possible association between the polymorphism of the (-670 A/G) Fas/Apo1 gene promoter and susceptibility to Crohn's disease (CD) and ulcerative colitis (UC) in the Tunisian population. METHODS: The (-670 A/G) Fas polymorphism was analyzed in 105 patients with CD, 59 patients with UC, and 100 controls using the polymerase chain reaction restriction fragment length polymorphism method. RESULTS: Significantly lower frequencies of the Fas -670 A allele and A/A homozygous individuals were observed in CD and UC patients when compared with controls. Analysis of (-670 A/G) Fas polymorphism with respect to sex in CD and UC showed a significant difference in A/A genotypes between female patients and controls (P corrected = 0.004 in CD patients and P corrected = 0.02 in UC patients, respectively). Analysis also showed a statistically significant association between genotype AA of the (-670 A/G) polymorphism and the ileum localization of the lesions (P corrected = 0.048) and between genotype GG and the colon localization (Pcorrected = 0.009). The analysis ofinflammatory bowel disease patients according to clinical behavior revealed no difference. CONCLUSION: Fas-670 polymorphism was associated with the development of CD and UC in the Tunisian population. | Walid Ben Aleya Imen Sfar Leila Mouelhi Houda Aouadi Mouna Makhlouf Salwa Ayed-Jendoubi Samira Matri Azza Filali Taoufik Najjar Taeib Ben Abdallah Khaled Ayed Yousr Gorgi | 2009 | World Journal of Gastroenterology2009，15，29： | 3 |
| 4 | EXISTENCE AND STABILITY RESULTS FOR GENERALIZED FRACTIONAL DIFFERENTIAL EQUATIONS显示文摘In this paper,a sufficient conditions to guarantee the existence and stability of solutions for generalized nonlinear fractional differential equations of orderα(1<α<2)are given.The main results are obtained by using Krasnoselskii's fixed point theorem in a weighted Banach space.Two examples are given to demonstrate the validity of the proposed results. | A.BEN MAKHLOUF D.BOUCENNA M.A.HAMMAMI | 2020 | Acta Mathematica Scientia2020，40，1： | 2 |
| 5 | Natural evolution of hepatitis C virus infection in hemodialysis Tunisian patients and CTLA-4 SNP's显示文摘AIM: To analyze the polymorphisms of CTLA-4 gene involved in the response against hepatitis C virus(HCV) infection.METHODS: We recruited 500 hemodialysed patients from several hemodialysis centers, all HCV-antibody positive, spread over different regions of Tunisia, as part of a national survey in 2008 conducted in the laboratory of immunology at the Charles Nicolle hospital Tunisia, classified into two groups G1(PCR+) and G2(PCR-) according to the presence or absence of viral RNA. Of these patients, 307 were followed prospectively on a viral molecular level over a period from 2002 to 2008, divided into two groups based on the persistence and viral clearance. PCR-RFLP was performed for the analysis of SNPs(+49) A/G and(+6230) G/A CTLA-4 for these 500 patients and 358 healthy controls.RESULTS: Analysis of clinical and virological charac-teristics of our cohort suggests a nosocomial infection in our hemodialysed patients with transfusion history as a primary risk factor and a predominance of genotype 1b. The haplotype analysis revealed an increase of frequencies of GG(+49)/(CT60) CTLA-4 in the entire patients group compared to controls(P = 0.0036 and OR = 1.42; 95%CI: 1.12-1.79, respectively). This haplotype is therefore associated with susceptibility to HCV infection. CONCLUSION: Our study suggests a possible role of CTLA-4 polymorphisms in the outcome of HCV infection in the Tunisian hemodialysed population. | Leila Ksiaa Cheikhrouhou Yousr Lakhoua-Gorgi Imen Sfar Salwa Jendoubi-Ayed Houda Aouadi Mouna Makhlouf Khaled Ayed Taieb Ben Abdallah | 2015 | World Journal of Gastroenterology2015，21，35： | 2 |
| 6 | Second-trimester pregnancy termination:comparison of threedifferent methods 显示文摘 | Makhlouf A AL-Hussaini T Habib D | 2003 | Obstet Gynaecol2003，23，4： | 1 |
| 7 | Vascular endothelial growth factor level in chronic liver diseases 显示文摘 | Makhlouf MM Awad A Zakhari MM | 2002 | J Egypt Soc Parasitol2002，32，： | 1 |
| 8 | Nucleation mechanism of the eutectic phases in aluminum-silicon hypo-eutectic alloys显示文摘 | Sumanth S Yancy W R Makhlouf M Makhlouf | 2004 | Acta Materialia2004，52，4： | 1 |
| 9 | Effect of key alloying elements on the feeding characteristics of aluminum-silicon casting alloys 显示文摘 | Dash M Makhlouf M | 2001 | JournalofLight Metals2001，，4： | 1 |
| 10 | Matemal and fetal serum nitric oxide (NO) concentrations in normal pregnancy, pre- eclampsia and eclampsia显示文摘 | Shaamash AH Elsnosy ED Makhlouf AM | 2000 | Int J Gynaecol Obstet2000，68，3： | 1 |
| 11 | Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the duodenum : a clinicopathologic, immunohistochemical, and molecular genetic study of 167 cases显示文摘 | Miettinen M Kopczynski J Makhlouf H R | 2005 | Am J Surg Pathol2005，27，5： | 1 |
| 12 | Epithelioid he- mangioendothelioma of the liver: a Clinicopathologic study of 137 cases显示文摘 | Makhlouf HR Ishak KG Goodman ZD | 1999 | Cancer1999，85，： | 1 |
| 13 | Epithelioid hemangioendothelioma of the liver:a clinicopathologic study of 137 cases显示文摘 | Makhlouf HR Ishak KG Goodman ZD | | 0，，3： | 1 |
| 14 | Notes on formal deformations of Hom-associative and Hom-Lie algcbras显示文摘 | Makhlouf A Silvestrov S | 2010 | Forum Mathernati?cum2010，22，4： | 1 |
| 15 | Optimum conditions for pressureless infiltration of SiCp perform by aluminum alloys 显示文摘 | Pech-Canul M I Katz R N Makhlouf M M | 2000 | J Mater Proc Techn2000，108，： | 1 |
| 16 | Calcifying nested stromal-epithelial tumors of the liver:A clinicopathologic,immunohistochemical,and molecular genetic study of 9 cases with a long-term follow-up显示文摘 | Makhlouf H R Abdul-Al H M Wang G | 2009 | Am J Surg Pathol2009，33，： | 1 |
| 17 | Structural evolution and magnetic - properties of nano - granular metallic alloys 显示文摘 | SUMIYAMA K SUZUKI K MAKHLOUF S A | 1995 | J Non - Cryst Solids1995，193，： | 1 |
| 18 | Numerical prediction of mag- net hydrodynarnic flow in continuous casting process显示文摘 | Ishii T Sazhin S S Makhlouf | 1996 | Iron making and Steeling1996，23，3： | 1 |
| 19 | Melanoma markers in angiomyolipoma of the liver and kidney:a comparative study显示文摘 | Makhlouf HR Ishak KG Shekar R | 2002 | Arch Pathol Lab Med2002，126，1： | 1 |
| 20 | Sequential clomiphenecitrate/hMG versus hMG for ovulation induction inclomiphene citrate-resistant women 显示文摘 | Abdelazim IA Makhlouf HH | 2013 | Arch GynecolObstet2013，287，3： | 1 |
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