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| 1 | Epistaxis in end stage liver disease masquerading as severe upper gastrointestinal hemorrhage显示文摘AIM:To describe the prevalence,diagnosis,treatment,and outcomes of end stage liver disease(ESLD) patients with severe epistaxis thought to be severe upper gastrointestinal hemorrhage(UGIH).METHODS:This observational single center study included all consecutive patients with ESLD and epistaxis identified from consecutive subjects hospitalized with suspected UGIH and prospectively enrolled in our databases of severe UGIH between 1998 and 2011.RESULTS:A total of 1249 patients were registered for severe UGIH in the data basis,461(36.9%) were cirrhotics. Epistaxis rather than UGIH was the bleeding source in 20 patients. All patients had severe coagulopathy. Epistaxis was initially controlled in all cases. Fifteen(75%) subjects required posterior nasal packing and 2(10%) embolization in addition to correction of coagulopathy. Five(25%) patients died in the hospital,12(60%) received orthotopic liver transplantation(OLT),and 3(15%) were discharged without OLT. The mortality rate was 63% in patients without OLT.CONCLUSION:Severe epistaxis in patients with ESLD is(1) a diagnosis of exclusion that requires upper endoscopy to exclude severe UGIH;and(2) associated with a high mortality rate in patients not receiving OLT. | Marine Camus Dennis M Jensen Jason D Matthews Gordon V Ohning Thomas O Kovacs Rome Jutabha Kevin A Ghassemi Gustavo A Machicado Gareth S Dulai | 2014 | World Journal of Gastroenterology2014，20，38： | 3 |
| 2 | Trough levels and antibodies to infliximab may not predict response to intensification of infliximab therapy in patients with inflammatory bowel disease显示文摘 | Benjamin Pariente Guillaume Pineton de Chambrun Roman Krzysiek Marine Desroches Gauthier Louis Chiara De Cassan Clotilde Baudry Jean‐Marc Gornet Pierre Desreumaux Dominique Emilie Jean‐Frédéric Colombel Matthieu Allez | 2011 | Inflamm Bowel Dis2011，，7： | 2 |
| 3 | First characterization of endophytic Corynespora cassiicola isolates with variant cassiicolin genes recovered from rubber trees in Brazil显示文摘Corynespora cassiicola is the causal agent of Corynespora Leaf Fall(CLF)disease.CLF is one of the most important fungal diseases of rubber trees in Asia and Africa but disease outbreaks have not been reported in South America.Cassiicolin,a small cysteine-rich glycoprotein secreted by the pathogenic C.cassiicola isolate CCP,was previously identified as a potential disease effector in rubber tree.Recently,the cassiicolin-encoding gene(Cas1)was characterized and shown to be expressed in the early phase of infection.In this study,we investigated whether previously undetected strains of C.cassiicola are present in South American rubber plantations by examining the fungal endophyte population found in asymptomatic rubber tree leaves.Four isolates were identified as C.cassiicola.Genes encoding new forms of the cassiicolin precursor protein(Cas3 and Cas4)were identified from these isolates.Three of four isolates were able to induce symptoms on the cultivar they were isolated from in a detached leaf assay,with different kinetics and intensities.One isolate had the same pathogenicity profile as the pathogenic isolate CCP;the other two isolates developed symptoms late during the course of infection,suggesting saprotrophic capabilities.However,no Cas3 or Cas4 transcripts could be detected upon inoculation with the endophytic isolates,whereas the reference gene Cas1 was expressed upon inoculation with the CCP isolate.This work demonstrated that C.cassiicola is present in South America in an endophytic form and that it may evolve from an endophytic to a saprophytic or even potentially pathogenic life style. | Marine Déon Ana Scomparin Aude Tixier Carlos R.R.Mattos Thierry Leroy Marc Seguin Patricia Roeckel-Drevet Valérie Pujade-Renaud | 2012 | Fungal Diversity2012，，3： | 2 |
| 4 | Tei-index in patients with mild-to-moderate congestive heart failure显示文摘 | Bruch C Schmermund A Marin D | | 0，，： | 2 |
| 5 | Normal Spinal Bone Marrow in Adult:Dynamic Gadolinium-enhanced MR Imaging显示文摘 | Jean M Marine D Eric L | 2003 | Radiology2003，229，： | 1 |
| 6 | Tei-index in patients with mild-to-moderate congestive heart failure显示文摘 | Bruch C Schmermund A Marin D | 2000 | Eur Heart J2000，21，22： | 1 |
| 7 | A new intemational division of labor in Eu-rope: outsourcing and offshoring to Eastern europe 显示文摘 | D MARIN | 2006 | Journal of the European Economic Association2006，4，23： | 1 |
| 8 | Multiplex PCR assay for the identification and differentiation of all Brucella species and the vaccine strains BruceUa abortus S19 and RBS1 and Brucella melitensis Revl显示文摘 | Garcia Y D Marin C M de Miguel M J | | 0，，04： | 1 |
| 9 | Dilution of mainstreamtobacco smoke and its effects upon the evaporation anddiffusion of nicotine显示文摘 | Lewis D A Colbeck I Mariner D C | 1995 | Journal of Aerosol Science1995，26，5： | 1 |
| 10 | Efficient wireless non-radiative mid-range energy transfer 显示文摘 | Aristeidis Karalis J D Joannopoulos Marin Soljacic | 2008 | Annals of Physics2008，323，： | 1 |
| 11 | Boron removal by the duckweed Lemna gibba : A potential method for the remediation of boron-pol- luted waters显示文摘 | MARIN C M D ORON G | 2007 | Water Research2007，41，： | 1 |
| 12 | Sumatriptan and cerebral biood flow velocity change during migraine attacks显示文摘 | Matteis G D Marin C | 1997 | headache1997，37，10： | 1 |
| 13 | Bile acid patterns in meconium are influenced by cholestasis of pregnancy and not altered by ursodeoxycholic acid treatment显示文摘 | Rodfigues C M Marin J G Brites D | 1999 | Gut1999，45，3： | 1 |
| 14 | Cholinergic markers in elderly patients with early signs of Alzheimer's disease 显示文摘 | Davis KL Mohs RC Marin D | 1999 | J AMA1999，281，： | 1 |
| 15 | Focal nodular hy?perplasia: typical and atypical MRI findings with emphasis on the use of contrast media显示文摘 | Marin D Brancatelli G Federle MP | 2008 | Clin Radiol2008，63，5： | 1 |
| 16 | VEGF-mediated tumour angiogenesis: a new target for cancer therapy显示文摘 | Martiny-Baron G Marine D | 1995 | Curr Opin Biotechnol1995，6，6： | 1 |
| 17 | A numerical study of cell merger over Cuba - Part Ⅰ : Implementation of the ARPS/MM5 models显示文摘 | Pozo D Borrajero I Marin J C | 2006 | Annales Geophysicae2006，24，11： | 1 |
| 18 | Effects of zearalenone and its derivatives on porcine immune response 显示文摘 | Marin D E Taranu I Burlacu R | 2011 | Toxicon in Vitro2011，25，8： | 1 |
| 19 | As-sessment of genetic stability of Brucella melitensis Rev 1 vaccine strain by multiple-locus variable-num- ber tandem repeat analysis 显示文摘 | Garcia-Yoldi D Le Fleche P Marin C M | 2007 | Vaccine2007，25，15： | 1 |
| 20 | Low-tube-voltage,high-tub-current muliidetector abdominal CT:intproved image quality and decreased radiation dose with adaptive statistical iterative reconstruction algorithm-initial clinical experience显示文摘 | Marin D Nelson RC Sehindem ST et at | 2010 | Radioingy2010，，： | 1 |
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