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| 1 | Retrospective cohort study Lower incidence of complications in endoscopic nasobiliary drainage for hilar cholangiocarcinoma显示文摘AIM:To identify the most effective endoscopic biliary drainage technique for patients with hilar cholangiocarcinoma.METHODS:In total,118 patients with hilar cholangiocarcinoma underwent endoscopic management[endoscopic nasobiliary drainage(ENBD)or endoscopic biliary stenting]as a temporary drainage in our institution between 2009 and 2014.We retrospectively evaluated all complications from initial endoscopic drainage to surgery or palliative treatment.The risk factors for biliary reintervention,post-endoscopic retrograde cholangiopancreatography(post-ERCP)pancreatitis,and percutaneous transhepatic biliary drainage(PTBD)were also analyzed using patient-and procedure-related characteristics.The risk factors for bilateral drainage were examined in a subgroup analysis of patients who underwent initial unilateral drainage.RESULTS:In total,137 complications were observed in92(78%)patients.Biliary reintervention was required in 83(70%)patients.ENBD was significantly associated with a low risk of biliary reintervention[odds ratio(OR)=0.26,95%CI:0.08-0.76,P=0.012].Post-ERCP pancreatitis was observed in 19(16%)patients.An absence of endoscopic sphincterotomy was significantly associated with post-ERCP pancreatitis(OR=3.46,95%CI:1.19-10.87,P=0.023).PTBD was required in 16(14%)patients,and Bismuth type III or IV cholangiocarcinoma was a significant risk factor(OR=7.88,95%CI:1.33-155.0,P=0.010).Of 102 patients with initial unilateral drainage,49(48%)required bilateral drainage.Endoscopic sphincterotomy(OR=3.24,95%CI:1.27-8.78,P=0.004)and Bismuth II,III,or IV cholangiocarcinoma(OR=34.69,95%CI:4.88-736.7,P<0.001)were significant risk factors for bilateral drainage.CONCLUSION:The endoscopic management of hilar cholangiocarcinoma is challenging.ENBD should be selected as a temporary drainage method because of its low risk of complications. | Kazumichi Kawakubo Hiroshi Kawakami Masaki Kuwatani Shin Haba Taiki Kudo Yoko A Taya Shuhei Kawahata Yoshimasa Kubota Kimitoshi Kubo Kazunori Eto Nobuyuki Ehira Hiroaki Yamato Manabu Onodera Naoya Sakamoto | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，9： | 26 |
| 2 | Preoperative staging by multidetector-row computed tomography in patients with rectal carcinoma显示文摘 | Mstsuoka H Nakamura A Masaki T | 2002 | Am J Surg2002，184，2： | 2 |
| 3 | NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis 显示文摘 | Masaki T Jay A Berzofsky | 2007 | Trends Im- munol2007，28，11： | 1 |
| 4 | Genetic changes of coxsackievirus A16 and enterovirus 71 isolated from hand, foot, and mouth disease patients in Toyama, Japan between 1981 and 2007 显示文摘 | Iwai M Masaki A Hasegawa S | 2009 | Jpn J Infect Dis2009，62，4： | 1 |
| 5 | Rationale for performing penetrating keratoplasty rath- er than DSAEK in patients with bullous keratopathy in Japan 显示文摘 | Yokogawa H Kobayashi A Saito Y Yamazaki N Masaki T Sug- iyama K | 2012 | Ophthalmic Surg Lasers Imaging2012，43，6： | 1 |
| 6 | Preoperative staging by muhidetector-row computed tomography in patients with rectal carcinoma 显示文摘 | Matsuoka H Nakamura A Masaki T | 2002 | Am J Surg2002，184，2： | 1 |
| 7 | Methane recovery from methane hydrate using pressurized CO2显示文摘 | Masaki O Yuki A Masaru W | | 0，，： | 1 |
| 8 | Compact, High Peak Power, Passively Q-switched Micro-laser for Ignition of Engines 显示文摘 | MASAKI T TAKAYUKI I AKIHIRO A | 2010 | IEEE Journal of Quantum Electronics2010，46，2： | 1 |
| 9 | Gene therapy for experimental critical limb ischemia:cceleration of limb loss by overexpression of VEGF165 but not of FGF-2显示文摘 | Masaki I Yonemitsu Y Yamashita A | 2002 | Circ Res2002，90，： | 1 |
| 10 | Genetic changes of coxsackievirus A16 and enterovirus 71 isolated from hand, foot, and mouth disease patients in Toyama, Japan between 1981 and 2007显示文摘 | Iwai M Masaki A Hasegawa S | 2009 | Jpn J Infect Dis2009，62，4： | 1 |
| 11 | Structure of recombinant human serum albumin from Pichia pastoris显示文摘 | OHTANI W MASAKI A IKEDA Y | 1997 | Yakugaku Zasshi1997，117，： | 1 |
| 12 | Expression of nm23-H1 gene product in esophageal squqmous cell carcinoma and its association with vessel invasion and survival显示文摘 | Masaki T Takanori A Yasunori M | 2001 | BMC Cancer2001，1，： | 1 |
| 13 | A mathematical model of a shallow and eutrophic lake(the Keszthely basin,lake balaton)simulation of restorative manipulations显示文摘 | MASAKIS A S MOTOYUKI S | 2001 | Water Research2001，35，7： | 1 |
| 14 | Comparison between endorectal coil and pelvic phased-array coil magnetic resonance imaging in patients with anorectal tumor显示文摘 | Matsuoka H Nakamura A Masaki T | 2003 | Am J Surg2003，185，4： | 1 |
| 15 | Protein kinase C in transmembrane signalling显示文摘 | Farago A Moil Y Masaki H | 1990 | Biochen J1990，268，： | 1 |
| 16 | Tropical, subtropical and temperate life cycles in ground crickets显示文摘 | Masaki S Shirado I Nagase A | 1987 | Insect Science and its Application1987，8，： | 1 |
| 17 | Characterization of carbon-coated natural graphite as a lithium ion battery anode material显示文摘 | Hongyu W Masaki Y Takeshi A | 2002 | J Electrochem Soc2002，149，4： | 1 |
| 18 | The occurrence of vomifoliol, dehydrovomifoliol and dihydrophaseic acid in the hoots of 'Kidney bean'显示文摘 | Mitsuo T Masaki A Nobukatsu K | 1973 | Chem Lett1973，，3： | 1 |
| 19 | The effects of low-intensity pulsed ultrasound exposure on gingival ceils 显示文摘 | Shiraishi R Masaki C Toshinaga A | 2011 | J Periodontol2011，82，10： | 1 |
| 20 | Creep-strengthening of steel at high temperatures using nano-sized carbonitride dis- persions显示文摘 | MASAKI T FUJIO A KOTA S | 2003 | Nature2003，424，7： | 1 |
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