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| 1 | Helicobacter pylori recurrence after eradication in Latin America:Implications for gastric cancer prevention显示文摘AIM To estimate Helicobacter pylori(H. pylori) recurrence rate in Latin America, a region with a significant H. pylori prevalence and gastric cancer burden.METHODS Pub Med, LILACS, Sci ELO, Cochrane databases and abstracts from relevant meetings were reviewed. Information collected included: Participants' characteristics, recruitment strategy, diagnostic modality, treatment arms, follow-up and recurrence rates. Recurrence was calculated using 100-patients-year rates, and data were pooled using a random effects model. The I2 statistic assessed between study heterogeneity. Meta-regression analyses evaluated for effect modifying variables. RESULTS Literature search yielded 163 articles. Twelve studies involving 4848 patients from 9 countries met inclusion criteria. Four hundred and thirty-two reinfections were recorded in 5487 person-years of follow-up. Pooled analysis showed a recurrence rate of 7.9 cases per 100 person-years(95%CI: 5.3-10.5). Meta-regression revealed that neither the antibiotic schema, a second antibiotic course, nor the diagnostic modality had an impact on the observed risk of recurrence. The recurrence rate in the first year after treatment, predominantly recrudescence,was 11.2(6.1-16.4) per 100 patient years. Recurrence in subsequent years, was only 6.2(3.8-8.7).CONCLUSION H. pylori recurrence rates in Latin America are significant, and with geographic variability, yet are acceptable based upon the current literature for consideration of large scale intervention trials. Further research in Latin America is warranted to evaluate the efficacy, cost-effectiveness, and potential adverse outcomes of proposed eradication programs. | Juan E Corral Robertino Mera Corey W Dye Douglas R Morgan | 2017 | World Journal of Gastrointestinal Oncology2017，9，4： | 5 |
| 2 | Carbon-rich SiCN ceramicsderived from phenyl-containing poly( silylcarbodiimides) 显示文摘 | Mera G Riedel R Poli F | 2009 | Journal of the European Ceramic Society2009，29，13： | 1 |
| 3 | Inducible nitric oxide synthase,nitrotyrosine,and apoptosis in Helicobacter pylori gastritis:effect of antibiotics and antioxidants 显示文摘 | Mannick EE Bravo LE Zarama G Realpe JL Zhang XJ Ruiz B Eonthan ETH Mera R Miller MJL Correa P | 1996 | Cancer Res1996，56，： | 1 |
| 4 | Polymer-derived ce- ramics; 40 years of research and innovation in advanced ce- ramics 显示文摘 | Colombo P Mera G Riedel R | 2010 | J Am Ceram Soc2010，93，7： | 1 |
| 5 | Interleukin-1 betaand interleukin-1 receptor antagonist gene polymorphismsand gastric cancer: a meta-analysis 显示文摘 | Camargo MC Mera R Correa P | 2006 | Cancer EpidemiolBiomarkers Prev2006，15，： | 1 |
| 6 | First report of ascochyta blight of chickpea caused by Ascochyta rabiei in Chile 显示文摘 | Galdames R Mera M | 2003 | Plant Dis2003，87，5： | 1 |
| 7 | Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer:a meta-analysis显示文摘 | Camargo M C Mera R Correa P | 2006 | Cancer Epidemiol Biomarkers Prev2006，15，9： | 1 |
| 8 | Polymer-derived ceramics:40 years of research and innovation in advanced ceramics显示文摘 | Colombo P Mera G Riedel R | | 0，，07： | 1 |
| 9 | Silicon-based polymer-derived ceramics:synthesis properties and applications-a review显示文摘 | Riedel R Mera G Hauser R | | 0，，1330： | 1 |
| 10 | Human faseioliasis in Argentina: retrospective overview, critical analysis and baseline for future research显示文摘 | Mera y Sierra R Agramunt VH Cuervo P | 2011 | Parasit Vectors2011，4，： | 1 |
| 11 | Polymer-derived ceramics: 40 years of research and innovation in advanced ceramics 显示文摘 | COLOMBO P MERA G RIEDEL R | 2010 | Journal of the American Ceramic Society2010，93，7： | 1 |
| 12 | Thermal decomposition of carbon-rich polymer-derived silicon carbonitrides leading to ceramics with high specific surface area and tunable micro- and mesoporosity 显示文摘 | Prasad R M Mera G Morita K | 2012 | J Eur Ceram Soc2012，32，2： | 1 |
| 13 | Impact of Helicobacter pylori infection on growth of children : a prospective cohort study 显示文摘 | Bravo LE Mera R Reina JC | 2003 | J Pediatr Gastroenterol Nutr2003，37，5： | 1 |
| 14 | Polymer-derived ceramics: 40 years of research and innovation in advanced ceramics 显示文摘 | COLOMOB' P MERA G RIEDEL R SORARU G D | 2010 | J Am Ceram Soc2010，93，： | 1 |
| 15 | Interleukin-1 beta and interleu- kin-1 receptor antagonist gene polymorphisms and gastric cancer:a meta-analysis显示文摘 | Camargo MC Mera R Correa P | 2006 | Cancer Epidemiol Biomarkers Prev2006，15，9： | 1 |
| 16 | Silicon-Based Polymer-Derived Ceramics:Synthesis Properties and Applications-A Review显示文摘 | Riedel R Mera G Hause R | | 0，，： | 1 |
| 17 | Impact of Helicobacter pylori infection on growth of children:a prospective cohort study 显示文摘 | Bravo LE Mera R Reina JC | 2003 | J Pediatr Gastroenterol and Nutr2003，37，5： | 1 |
| 18 | Polymer-derived ceramics:40 years of research and innovation in advanced ceramics显示文摘 | Colombo P Mera G Riedel R | | 0，，07： | 1 |
| 19 | Long term follow up of pa-tients treated for Helicobacter pylori infection显示文摘 | Mera R Fontham ET Bravo LE | 2005 | Gut2005，54，11： | 1 |
| 20 | Long term follow up of patients treated for Helicobacter pylori infection显示文摘 | Mera R Fontham ET Bravo LE | 2005 | Grit2005，54，11： | 1 |
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