|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Adult-to-adult living-donor liver transplantation: The experience of the Université catholique de Louvain显示文摘Background: Liver transplantation is the treatment for end-stage liver diseases and well-selected malignancies. The allograft shortage may be alleviated with living donation. The initial UCLouvain experience of adult living-donor liver transplantation(LDLT) is presented. Methods: A retrospective analysis of 64 adult-to-adult LDLTs performed at our institution between 1998 and 2016 was conducted. The median age of 29(45.3%) females and 35(54.7%) males was 50.2 years(interquartile range, IQR 32.9–57.5). Twenty-two(34.4%) recipients had no portal hypertension. Three(4.7%) patients had a benign and 33(51.6%) a malignant tumor [19(29.7%) hepatocellular cancer, 11(17.2%) secondary cancer and one(1.6%) each hemangioendothelioma, hepatoblastoma and embryonal liver sarcoma]. Median donor and recipient follow-ups were 93 months(IQR 41–159) and 39 months(22–91), respectively. Results: Right and left hemi-livers were implanted in 39(60.9%) and 25(39.1%) cases, respectively. Median weights of right-and left-liver were 810 g(IQR 730–940) and 454 g(IQR 394–534), respectively. Graft-to-recipient weight ratios(GRWRs) were 1.17%(right, IQR 0.98%-1.4%) and 0.77%(left, 0.59%-0.95%). One-and five-year patient survivals were 85% and 71%(right) vs. 84% and 58%(left), respectively. Oneand five-year graft survivals were 74% and 61%(right) vs. 76% and 53%(left), respectively. The patient and graft survival of right and left grafts and of very small( < 0.6%), small(0.6%–0.79%) and large( ≥0.8%) GRWR were similar. Survival of very small grafts was 86% and 86% at 3-and 12-month. No donor died while five(7.8%) developed a Clavien–Dindo complication IIIa, IIIb or IV. Recipient morbidity consisted mainly of biliary and vascular complications; three(4.7%) recipients developed a small-for-size syndrome according to the Kyushu criteria. Conclusions: Adult-to-adult LDLT is a demanding procedure that widens therapeutic possibilities of many hepatobiliary diseases. The donor procedure can be done safely with low morbidity. The recipient operation carries a major morbidity indicating an important learning curve. Shifting the risk from the donor to the recipient, by moving from the larger right-liver to the smaller left-liver grafts, should be further explored as this policy makes donor hepatectomy safer and may stimulate the development of transplant oncology. | Samuele Iesari Milton Eduardo Inostroza Nú?ez Juan Manuel Rico Juri Olga Ciccarelli Eliano Bonaccorsi-Riani Laurent Coubeau Pierre-Fran?ois Laterre Pierre Goffette Chantal De Reyck Beno?t Lengelé Pierre Gianello Jan Lerut | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，2： | 5 |
| 2 | Comparative Effects of Low and High Doses of the Angiotensin-Converting Enzyme Inhibitor, Lisinopril, on Morbidity and Mortality in Chronic Heart Failure显示文摘 | Milton Packer Philip A. Poole-Wilson Paul W. Armstrong John G.F. Cleland John D. Horowitz Barry M. Massie Lars Rydén Kristian Thygesen Barry F. Uretsky | 1999 | Circulation1999，，23： | 2 |
| 3 | Evaluation of the intelisite capsule to deliver theophylline and frusemide tablets to the small intestine and colon显示文摘 | Clear N J Milton A Humphrey M | 2001 | Eur J Pharm Sci2001，13，4： | 1 |
| 4 | Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood显示文摘 | Celedón JC Milton DK Ramsey CD | 2007 | J Allergy Clin Immunol2007，120，1： | 1 |
| 5 | Optimizing the superlens, manipulating geometry to enhance the resolution显示文摘 | PODOLSKIY V A KUHTA N A MILTON G W | 2005 | Appl Phys Lett2005，87，23： | 1 |
| 6 | Evaluating median cross-over likelihoods with clustered accident counts:an empirical inquiry using random effects negative binomial model显示文摘 | Shankar V N Albin R B Milton J C | 1998 | Transportation Research Record1998，1635，： | 1 |
| 7 | Remote sensing of vegetation responses to natural and cultural environment condition显示文摘 | Milton N M Monat D A | | 0，，08： | 1 |
| 8 | Microstructural Analyses and Wear Behavior of the Cemented Carbide Tools after Laser Surface Treatment and PVD Coating显示文摘 | DAVI N ANSELMOD MILTON L | 2013 | Applied Surface Science2013，282，： | 1 |
| 9 | Evaluation of the In- telisite capsule to deliver theophylline and frusemide tablets to the small intestine and colon 显示文摘 | Clear N J Milton A Humphrey M | 2001 | Eur J Pharm Sci2001，13，4： | 1 |
| 10 | Solutions in folded geometries,and associated cloaking due to anomalous resonance显示文摘 | Milton G W Nicorovici N A P McPhedran R C | | 0，，： | 1 |
| 11 | Consensus recommendations for the management of chronic heart failure显示文摘 | Milton Packer J N Cohn W T Abraham | 1999 | Am J Cardiol1999，83，： | 1 |
| 12 | A growth theory for the insurance industry 显示文摘 | N MILTON | 2010 | Risk Management and Insurance Review2010，13，1： | 1 |
| 13 | Measurement of aerolein and 1, 3-butadiene in a single puff of cigarette smoke using lead-salt tunable diode laser infrared spectroscopy 显示文摘 | Thweatt W Dave Harward Charles N Parrish Milton E | 2007 | Spectrochimica Acta (Part A)2007，67，1： | 1 |
| 14 | The crystallization kinetics of glycine hydrochloride from“frozen” solution 显示文摘 | Milton N Nail S L Akers M J | 1997 | Cryo-Letters1997，18，： | 1 |
| 15 | Hf isotope ratio analysis using multi-collector inductively coupled plasma mass spectrometry:An evaluation of isobaric interference corrections显示文摘 | Chu N C Taylor R N Chavagnac V Nesbitt R W Boella R M Milton J A German C R Bayon G and Burton K | | 0，，12： | 1 |
| 16 | Role of hydrogen peroxide in the aethiology of Alzheimer' s disease: implications for treatment 显示文摘 | Milton N G | 2004 | Drugs Aging2004，21，2： | 1 |
| 17 | Effect of molasses on mimosine metabolism in goats fed fresh and dried leucaena with barely straw显示文摘 | ELLIOT R N MILTON B W FORD C W | 1985 | AustJ Agric Res1985，36，： | 1 |
| 18 | Highway accident severities and the mixed logit model: an exploratory empirical analysis显示文摘 | John C Milton Venky N Shankar and Fred L Mannering | 2008 | Accident Analysis & Prevention2008，40，1： | 1 |
| 19 | Measurement of excessive appetite and metabolic changes in Prader-Willi syndrome 显示文摘 | Holland AJ Treasure J Coskeran P Dallow J Milton N Hillhouse E | 1993 | Int J Obes Relat Metab Disord1993，17，9： | 1 |
| 20 | Role of hydrogen peroxide in the aetiology of Alzheimer's disease : implications for treatment 显示文摘 | Milton N G | 2004 | Drugs Aging2004，21，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员