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| 1 | Thymidine kinase gene mutation leads to reduced virulence of pseudorabies virus显示文摘To explore correlation between the tk gene structure of pseudorabies virus (PRV) and its virulence, to study the effect of the gene mutation on PRV biological properties, and to investigate mechinism of reduced virulence, thymidine kinase (TK)-deficient mutant of pseudorabies virus strain Hubei (PRV HB) was isolated by selection for resistance to 5-bromodeoxyuridine. The tk genes of PRV HB and its TK mutant were cloned and sequenced. 1587 base pairs of the tk gene and flanking regions of wild-type (wt) virus were sequenced, which included an open reading frame (ORF) of 1098 bp encoding a protein of 366 amino acids. The ORF contained two 137-bp repeated sequences, which were connected by an adenosine. 1458 bp of the tk and flanking regions of TK- mutant were sequenced. Analysis of the tk gene sequence of TK mutant indicated that one of 137 bp repeated sequence and the connecting adenosine in the tk gene of the wt virus was deleted and a repeated sequence of 8 nucleotides (GCGCGCC) was inserted. All | Pan, ZS Zhang, CY Ding, JH Min, P | 2001 | Chinese Science Bulletin2001，46，23： | 2 |
| 2 | Clinical outcomes of endoscopic submucesal dissection (ESD) for treating early gastric cancer:Comparsion with endoscopic mucosal resection after circumferential precutting (EMR-P)显示文摘 | Min BH Lee JH Kim JJ | 2009 | Digestive and Liver Disease2009，41，3： | 1 |
| 3 | Structure of an HIF-1 alpha-pVHL complex: hydroxyproline recognition in signaling显示文摘 | Min JH Yang H Ivan M | 2002 | Science2002，296，5574： | 1 |
| 4 | Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: synthesis, characterization, and in vivo biodistribution 显示文摘 | Choi KY Min KH Na JH | 2009 | d Mater Chem2009，19，24： | 1 |
| 5 | Morphometric analysis of the working zone for endoscopic lumbar discectomy显示文摘 | Min JH Kang SH Lee JB | 2005 | J Spinal Disord Tech2005，18，2： | 1 |
| 6 | Extensively drug-resistant tuberculosis in South Korea: risk factors and treatment outcomes among patients at a tertiary referral hospital 显示文摘 | Jeon CY Hwang SH Min JH | 2008 | Clinical Infectious Diseases2008，46，1： | 1 |
| 7 | Stepwise evolution from a focal pure pulmonary ground-glass opacity nodule into an invasive lung adenocarcinoma: an observation for more than 10 years 显示文摘 | Min JH Lee HY Lee KS | 2010 | Lung Cancer2010，69，： | 1 |
| 8 | Tumoral acidic pH-responsive MPEG-poly (p-amino ester) polymeric micelles for cancer targeting therapy 显示文摘 | Min KH Kim JH Bae SM | 2009 | J Control Release2009，144，： | 1 |
| 9 | Changes in sagittal alignment after restoration of lower lumbar lordosis in patients with degenerative f lat back syndrome显示文摘 | Jang JS Lee SH Min JH | 2007 | J Neurosurg Spine2007，7，4： | 1 |
| 10 | Endoscopic resection for early gastric cancer beyond absolute indication with emphasis on con- troversial issues 显示文摘 | Min YW Lee JH | 2014 | J Gastric Cancer2014，14，1： | 1 |
| 11 | Adenosine induces hemeoxygenase-1 expression in mieroglia through the activation of phosphatidylinositol 3 kinase and nuclear factor E2 related factor 2显示文摘 | Min KJ Kim JH Jou I | 2008 | Glia2008，56，9： | 1 |
| 12 | Inhibitory effect of butein on tumor necrosis factor alpha induced expression of cell ad hesion molecules in human lung epithelial cells via inhibition of reactive oxygen species generation,NF-kappaB activation and Akt phosphorylation显示文摘 | Jang JH Yang ES Min KJ | 2012 | Int J Mol Med2012，30，6： | 1 |
| 13 | Leiomyosarcoma of the rectum mimicking primary ovarian carcinoma : a case report 显示文摘 | Ouh YT Hong JH Min KJ | 2013 | J Ovarian Res2013，6，： | 1 |
| 14 | Anti complement activity of constituents from the stem-bark of Juglans mandshuriea显示文摘 | Min BS Lee SY Kim JH | 2003 | Biol Pharm Bull2003，26，7： | 1 |
| 15 | Collagenous fibril texture of the discoid lateral meniscus显示文摘 | Cui JH Min BH | 2007 | Arthroscopy2007，23，6： | 1 |
| 16 | The elinical study on hepat- ic dysfunction by long-time CsA therapy after renal transplan tation显示文摘 | Zhou JH Min ZI Zhu YH etal | 2001 | China J Organ Transplantation2001，23，4： | 1 |
| 17 | Electron donation mechanisms of β-carotene as a free radical scavenger显示文摘 | Lee JH Ozcelik B Min DB | 2003 | J Food Sci2003，68，3： | 1 |
| 18 | Laparoscopic repair of various types of biliary-enteric fistula : Three cases 显示文摘 | Lee JH Han HS Min SK | 2004 | Surg Endosc2004，18，2： | 1 |
| 19 | Role of pigment epitheliura-derived factor in the involution of hemangioma:autocrine growth inhibition of hemangioma-derived endothelial cells显示文摘 | Kim KJ Yun JH Heo JI Lee EH Min HS Choi TH Cho CH | 2014 | 454(2) :282-82014，454，2： | 1 |
| 20 | Dynamic CT evaluation of tumor vascularity in renal cell carcinoma显示文摘 | Wang JH Min PQ Wang PJ | 2006 | MR2006，186，： | 1 |
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