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| 1 | Association of homocysteine and smoking with cerebral microemboli in patients with mechanical heart valves:a transcranial Doppler study显示文摘Objectives Microembolic signals(MES)on transcranial Doppler(TCD)predict stroke and cognitive decline.Plasma levels of total homocysteine(tHcy),a prothrombotic factor,are higher in patients with microemboli in carotid stenosis and in patients with paradoxical embolism.In this study we assessed the association between the level of tHcy and the number of MES in patients with mechanical heart valves(MHVs).Methods TCD monitoring was performed to detect MES before and after breathing 100% oxygen and repeated every 2-4 weeks up to six times.results Twenty-five patients with MHVs(mean age:63.60±10.15 years)participated in this study;15 were men(66.47±7.25 years)and 10 were women(59.30±12.60 years).In total,there were 126 study visits.In multiple regression,higher tHcy was associated with more MES in both preoxygenation(OR 1.34(95%CI 1.07 to 1.68,P=0.009))and postoxygenation(OR 1.40(95% CI 1.07 to 1.83,P=0.01))phases.Current smoking and the length of time between the operation and monitoring also correlated with a higher number of MES before and after breathing oxygen,particularly in women.conclusions Higher tHcy and smoking were associated with a higher MES count in both preoxygenation and postoxygenation phases.Because smoking can be stopped and hyperhomocysteinaemia is treatable,these are clinically important findings. | Alicia Mattia M Reza Azarpazhooh Claudio Munoz Chrysi Bogiatzi Mackenzie A Quantz J David Spence | 2017 | Stroke & Vascular Neurology2017，2，4： | 2 |
| 2 | 显示文摘 | Butty J Peyghambarian N Mackenzie J D | 1996 | Appl Phys Lett1996，69，： | 1 |
| 3 | Chalcohalide glasses vibrational spectra of Ge-S-I glasses显示文摘 | HEO J MACKENZIE J D | 1989 | J Non Cryst Solids1989，24，111： | 1 |
| 4 | End-pumped,passively Q-switched Yb:YAG double-clad waveguide laser显示文摘 | Mackenzie J I Shepherd D P | 2002 | Optics Letters2002，27，24： | 1 |
| 5 | Hardness equation for ormosils 显示文摘 | Makishima A Mackenzie J D | 2000 | Journal of Sol-Gel Science and Technology2000，19，： | 1 |
| 6 | The elastic compensation method for limit and shakedown analysis:a review显示文摘 | D Mackenzie J T Boyle R Hamilton | 2000 | Journal of Strain Analysis2000，35，3： | 1 |
| 7 | Dolomite formation and biochemical cycles in the Phanerozoic显示文摘 | Burns S J MacKenzie J A Vasconcelos C | 2000 | Sedimentology2000，47，1： | 1 |
| 8 | The origin of lead in the organic horizon of tundra soils: atmospheric deposition,plant translocation from the mineral soil or soil mineral mixing 显示文摘 | KIAMINDER J FARMER J G MACKENZIE A B | 2011 | Science of the Total Environment2011，409，20： | 1 |
| 9 | Prostaglandin ( F and E, 2-and 3-series) production and cy- clooxygenase (COX-2) gene expression of wild and cultured broodstock of Senegalese sole (Solea senegalensis) 显示文摘 | NORAMBUENA F MACKENZIE S BELL J G | 2012 | General and Comparative Endocrinology2012，177，2： | 1 |
| 10 | Effects of sensor spatial resolution on landscape structure parameters显示文摘 | Benson B J MacKenzie M D | 1995 | Land- scape Ecology1995，10，2： | 1 |
| 11 | Effects of sensor spatial resolution on landscape structure parameters显示文摘 | BENSON B J MACKENZIE M D | 1995 | Landscape Ecology1995，10，2： | 1 |
| 12 | The composition range of alumino silicate geopolymers显示文摘 | Fletcher R A Mackenzie K J D Nieholson C L | 2005 | J Eur Ceram Soc2005，25，： | 1 |
| 13 | Improvement in screening performance and diagnosis of congenital hypothyroid- ism in Scotland 1979-2003 显示文摘 | Jones JH Mackenzie J Croft GA | 2006 | Arch Dis Child2006，91，8： | 1 |
| 14 | Salt tolerance of soybean vari- eties during germination and later growth 显示文摘 | Abel G H Mackenzie A J | 1964 | Crop Sci- ence1964，，4： | 1 |
| 15 | Randomized trial of breast irradiation schedules after lumpectomy for wom- en with lymph node-negative breast cancer 显示文摘 | Whelan T MacKenzie R Julian J | 2002 | J J Natt Cancer Inst2002，94，15： | 1 |
| 16 | The calcination of titania: IV the effect of additives on the anatase-mtile transformation 显示文摘 | Mackenzie K J D | 1975 | Transactions and Journal of the British Ceramic Society1975，74，： | 1 |
| 17 | Simplified lower bound limit analysis of pressurized cylinder/cylinder intersections using generalized yield criteria显示文摘 | R Hamilton D Mackenzie J Shi J T Boyle | 1996 | Int J Pres Ves and Piping1996，67，2： | 1 |
| 18 | 显示文摘 | Mackenzie K J D | 1975 | J Br Ceram Soc1975，74，： | 1 |
| 19 | Hydrogen peroxide without accidents 显示文摘 | MACKENZIE J | 1990 | Chemical Engineering1990，，6： | 1 |
| 20 | Physical properties of sol-gel coating显示文摘 | MACKENZIE J D BESCHER E P | 2000 | Journal of Sol-Gel Science and Technology2000，19，： | 1 |
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