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| 1 | B cell regulation in cancer and anti-tumor immunity显示文摘The balance between immune effector cells and immunosuppressive cells and how this regulates the tumor microenvironment has been well described.A significant contribution of immune regulatory cells,including regulatory T cells,to tumor progression has been widely reported.An emerging body of evidence has recently recognized a role for B cells in modulating the immune response to tumors and lymphoid malignancies.Regulatory B cells(Bregs)are a newly designated subset of B cells that have been shown to play a pivotal role in regulating immune responses involved in inflammation,autoimmunity and,more recently,cancer.Bregs can suppress diverse cell subtypes,including T cells,through the secretion of anti-inflammatory mediators,such as IL-10,and can facilitate the conversion of T cells to regulatory T cells,thus attenuating anti-tumor immune responses.Similar B-cell subpopulations have been reported to be recruited to the tumor but to acquire their immunosuppressive properties within the tumor bed and thereby attenuate anti-tumor immune responses.However,despite a pivotal role for Bregs in promoting inflammation and carcinogenesis,the phenotypic diversity of the cell surface markers that are unique to Bregs remains unclear in mice and humans.In this review,we summarize the characteristics of Bregs and review our current knowledge of Bregs and their inhibition of anti-tumor immune responses in murine tumor models and cancer patients. | Anushruti Sarvaria J Alejandro Madrigal Aurore Saudemont | 2017 | Cellular & Molecular Immunology2017，14，8： | 40 |
| 2 | Generation of natural killer cells from hematopoietic stem cells in vitro for immunotherapy显示文摘生来的杀手(NK ) 房间是天生的免疫系统的部分并且由于他们没有优先的促进感受性,杀死感染的房间或癌症房间的能力是为免疫疗法的一种诱惑选择。在整个过去的 20 年,不同的组能在 vitro 复制 NK 房间开发,并且 NK 房间个体发生学习提供了基础让协议的建立为免疫疗法在 vitro 生产 NK 房间。这里,我们简短讨论 NK 房间开发和 NK 房间免疫疗法途径。我们考察为在 vitro 的房间区别,干细胞采购被使用的、出版协议,质问的 NK 需要的因素,为好生产的未来方向练习协议。 | Martha Luevano Alejandro Madrigal Aurore Saudemont | 2012 | Cellular & Molecular Immunology2012，9，4： | 10 |
| 3 | nteraction between natural killer cells and regulatory 7 :ells: perspectives for immunotherapy显示文摘规章的 T (Treg ) 房间和生来的杀手(NK ) 房间是在免疫系统的关键播放器。在这二种房间类型之间的相互作用被报导了处于象怀孕那样的健康条件有益。然而,在象自体免疫的疾病和癌症那样的某些病理的情况中,这个相互作用能变得有害,当 Treg 房间被描述了压制 NK 房间,特别地,房间受动器工作损害 NK。这评论试图在健康、病理学的条件下面在在 Treg 房间和 NK 房间之间的相互作用上讨论最近的信息,到描述这个相互作用在发生的特定的条件,造血的干细胞区别和 immunotherapeutic 协议的优化上的这个相互作用的后果上的 Treg 房间的效果。 | Isabela Pedroza-Pacheco Alejandro Madrigal Aurore Saudemont | 2013 | Cellular & Molecular Immunology2013，10，3： | 5 |
| 4 | Donor selection-matching for mismatches显示文摘 | Perez-Rodriguez M Madrigal JA | 1999 | Heematologica1999，84，： | 1 |
| 5 | A contribution for characterizing measured three-phase unbalanced voltage sags algorithm显示文摘 | Madrigal M Rocha B H | 2007 | IEEE Trans on Power Delivery2007，22，3： | 1 |
| 6 | Biological-con-trol of peach twig blight(Monilinia-laxa)with Epi-coccum nigrum显示文摘 | Madrigal C Pascual S Melgarejo P | 1994 | Plant Pathology1994，43，3： | 1 |
| 7 | Trends in Power Quality Monitoring 显示文摘 | Parle J A Madrigal M Acha E | 2001 | Power Engineering Review IEEE2001，21，10： | 1 |
| 8 | Existence and determination of competitive equilibrium in unit commitment power pool auctions:price setting and scheduling alternatives显示文摘 | Quintana V H | 2001 | IEEE Transaction on Power Systems2001，16，3： | 1 |
| 9 | Cognitive and affective determinants of fan satisfaction with sporting event attendance 显示文摘 | Madrigal R | 1995 | Journal of Leisure Research1995，27，： | 1 |
| 10 | Residents' perceptions and the role of government显示文摘 | Madrigal Robert | 1995 | Annals of Tourism Research1995，22，： | 1 |
| 11 | Premature ovarian failure and fragile X female premutation carriers:no evidence for a skewed X-chromosome inactivation pattern显示文摘 | Rodriguez-Revenga L Madrigal I Badenas C | | MENOPAUSE-THE Journal OF THE NORTH AMERICAN MENOPAUSE SOCIETY0，，： | 1 |
| 12 | CCL2/MCP-1 modulation of microglial activation and proliferation 显示文摘 | Hinojosa AE Garcia-Bueno B Madrigal JL | 2011 | J Neuroinflammation2011，8，： | 1 |
| 13 | Astrocyte -derived MCP-1 mediates neuroprotective effects of noradrenaline 显示文摘 | MADRIGAL J L LEZA J C POLAK P | 2009 | Journal of Neuroseience2009，29，1： | 1 |
| 14 | Study of available bone for interforaminal implantstretment using cone-beam computed tomography显示文摘 | Madrigal C Ortega R Meniz C et al | 2008 | Med Oral Pathol Oral Cir Buca12008，13，5： | 1 |
| 15 | Stress-induced ox idalive changes in brain显示文摘 | Madrigal JL Garcia-Bueno P Caso JR | 2006 | CNS Neurol Disord Drug Targets2006，5，5： | 1 |
| 16 | Residents' perceptions and the role of govemment显示文摘 | MADRIGAL R | 1994 | Annals of Tourism Research1994，22，： | 1 |
| 17 | Stress-induced neuroinflammation , Mechanisms and new pharmacological targets 显示文摘 | Munhoz CD Garcia-Bueno B Madrigal J L | 2008 | BrazJMedBioIRes2008，41，12： | 1 |
| 18 | Langerhans cell histiocytosis: literature reviewand descriptive analysis of oral manifes- tations 显示文摘 | Madrigal -Martinez -Pereda C Guerrero -Rodrfguez V Guisado-Moya B | 2009 | Med OralPatol Oral Cir Bueal2009，14，5： | 1 |
| 19 | Peroxisome proliferator-activated receptor gamma activation decreases neuroiniflammation in brain after stress in rats显示文摘 | GARCIA-BUENO B MADRIGAL J L LIZASOAIN I | 2005 | Biol Psychiatry2005，57，： | 1 |
| 20 | Integrated software platform to teach different electricity spot market architectures显示文摘 | Madrigal M Flores M | 2004 | IEEE Transaction on Power Systems2004，19，1： | 1 |
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