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| 1 | 中国、上合组织与阿富汗重建:机遇和挑战显示文摘2001年,美国成功推翻了阿富汗塔利班政权,但却未能完成阿富汗的重建。2021年8月15日,时隔20年,塔利班成功返回喀布尔。这一戏剧性变化让国际社会强烈要求塔利班必须有序建立一个温和、包容的政府,同时切断与极端组织的一切联系。由于阿富汗的地缘优势及其地理位置与中国毗邻,中阿两国不仅需要传承睦邻友好关系,而且中国意图在阿的国家重建中发挥建设性作用。面对美国已把中国视为全面战略竞争对手的国际环境,中国将如何参与阿富汗和平重建,备受国际社会关注。本文认为,中国将一如既往地恪守“和平共处五项原则”,灵活推动多边机制参与阿富汗的国家重建。为此,上海合作组织将与联合国、二十国集团(G20)等多边机制积极协调,在维护地区安全、尊重多元文明与谋求共同发展的国际使命中扮演重要角色。 | 王黎 Nasrat Hameedullah Makam Khan Daim | 2022 | 武汉科技大学学报(社会科学版)2022，24，1： | 4 |
| 2 | Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation显示文摘Genome-wide association studies(GWASs) have been instrumental in understanding complex phenotypic traits. However, they have rarely been used to understand lineage-specific pathways and functions that contribute to the trait. In this study, by integrating lineage-specific enhancers from mesenchymal and myeloid compartments with bone mineral density loci, we were able to segregate osteoblast-and osteoclast(OC)-specific functions. Specifically, in OCs, a PU.1-dependent transcription factor(TF)network was revealed. Deletion of PU.1 in OCs in mice resulted in severe osteopetrosis. Functional genomic analysis indicated PU.1 and MITF orchestrated a TF network essential for OC differentiation. Several of these TFs were regulated by cooperative binding of PU.1 with BRD4 to form superenhancers. Further, PU.1 is essential for conformational changes in the superenhancer region of Nfatc1. In summary, our study demonstrates that combining GWASs with genome-wide binding studies and model organisms could decipher lineage-specific pathways contributing to complex disease states. | Heather A.Carey Blake E.Hildreth III Jennifer A.Geisler Mara C.Nickel Jennifer Cabrera Sankha Ghosh Yue Jiang Jing Yan James Lee Sandeep Makam Nicholas A.Young Giancarlo R.Valiente Wael N.Jarjour Kun Huang Thomas J.Rosol Ramiro E.Toribio Julia F.Charles Michael C.Ostrowski Sudarshana M.Sharma | 2018 | Bone Research2018，6，1： | 4 |
| 3 | Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem eells显示文摘 | Nayak T R Andersen H Makam V S | 2011 | ACS Nano2011，5，6： | 1 |
| 4 | Generalized epilepsy withfebrile seizures plus (GEFS^+) :Clinical spectrumin seven Italian families unrelated to SCN1 A, SCN1 B, and GABRG2 gene mutations 显示文摘 | Bonanni P Makame M Moro F | 2004 | Epilepsia2004，45，： | 1 |
| 5 | Cloning of the cDNA and gene for a human D2 dopamine receptor显示文摘 | Marchioni MA Makam H | 1998 | Proc Natl Sci USA1998，86，24： | 1 |
| 6 | Building Reliable MPLS Networks Using Path Protection Mechanism显示文摘 | HUANG C OWENS K MAKAM S | 2002 | IEEE Communications Magazine2002，40，3： | 1 |
| 7 | Graphene for controlled and accelerated osteogenic dif- ferentiation of human mesenchymal stem cells 显示文摘 | NAYAK T R HENRIK A MAKAM V S | 2011 | ACS Nano2011，5，6： | 1 |
| 8 | A path protection/restoration mechanism for MPLS networks显示文摘 | Changcheng Huang V Sharma Srinias Makam | 2000 | IETF Draft2000，2000，： | 1 |
| 9 | Cloning of the cDNA and gene for a human D 2 dopamine receptor 显示文摘 | Grandy D K Marchionni M A Makam H | 1989 | Proc Nail Acad Sci USA1989，86，： | 1 |
| 10 | Clo-ning of the cDNA and gene for a human D2 dopa-mine receptor显示文摘 | Grandy D K Marchionni M A Makam H | 1989 | Pros Natl Acad Sci USA1989，86，24： | 1 |
| 11 | Interactions among PIN-FORMED and P-glycoprotein auxin transporters in Arabidopsis显示文摘 | BLAKESLEE J J BANDYOPADHYAY A LEE O R MRAVEC J TITAPIWATANAKUN B SAUER M MAKAM SN CHENG Y | 2007 | Plant Cell2007，19，1： | 1 |
| 12 | Graphene for con-trolled and accelerated osteogenic differentiation of human mesen-chymal stem cells 显示文摘 | Nayak TR Andersen H Makam VS | 2011 | ACS Nano2011，5，6： | 1 |
| 13 | Building reliable MPLS networks using a path protection mechnism显示文摘 | OWENS K MAKAM S | 2002 | IEEE Communications Magazine2002，40，3： | 1 |
| 14 | Randomizedcontrolled study of excimer laser atherectomy fortreatment of femoropopliteal in-stent restenosis: initialresults from the EXCITE ISR trial显示文摘 | Dippel EJ Makam P Kovach R | 2015 | JACC CardiovascInterv2015，8，1： | 1 |
| 15 | Psychological well-being of orphans in Dar E1 Salaam, Tanzania显示文摘 | Makame V Ani C Grantham-McGregor S | 2002 | Acta Paediatr2002，91，4： | 1 |
| 16 | Psychological wellbeing of orphans in Dar E1 Salaam Tanzania 显示文摘 | Makame V Ani C Grantham-McGregor S | 2002 | Acta Paediatr2002，91，4： | 1 |
| 17 | A path protection/restoration mechanism for MPLS networks显示文摘 | Owens K Sharma V Makam S | 2001 | Internet Draft2001，31，3： | 1 |
| 18 | Cloning of the cDNA and gene for ahuman 132 dopamine receptor显示文摘 | Grandy DK Marchioni MA Makam H | 1989 | Proc Natl Sci USA1989，86，24： | 1 |
| 19 | Regiospeeific solid- phase synthesis of substituted 1,2,3 -triazoles 显示文摘 | Makam S Raghavendra Yulin Lain | 2004 | Tetrahedron Letters2004，45，： | 1 |
| 20 | Graphene for controlled and accelerated osteogenic differentiation of hu man mesenchymal stem cells 显示文摘 | Nayak T R Andersen H Makam V S | 2011 | ACS Nano2011，5，6： | 1 |
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