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| 1 | Advances in laparoscopy for acute care surgery and trauma显示文摘The greatest advantages of laparoscopy when compared to open surgery include the faster recovery times, shorter hospital stays, decreased postoperative pain, earlier return to work and resumption of normal daily activity as well as cosmetic benefits. Laparoscopy today is considered the gold standard of care in the treatment of cholecystitis and appendicitis worldwide. Laparoscopy has even been adopted in colorectal surgery with good results. The technological improvements in this surgical field along with the development of modern techniques and the acquisition of specific laparoscopic skills have allowed for its utilization in operations with fully intracorporeal anastomoses. Further progress in laparoscopy has included single-incision laparoscopic surgery and natural orifice trans-luminal endoscopic surgery. Nevertheless, laparoscopy for emergency surgery is still considered challenging and is usually not recommended due to the lack of adequate experience in this area. The technical difficulties of operating in the presence of diffuse peritonitis or large purulent collections and diffuse adhesions are also given as reasons. However, the potential advantages of laparoscopy, both in terms of diagnosis and therapy, are clear. Major advantages may be observed in cases with diffuse peritonitis secondary to perforated peptic ulcers,for example, where laparoscopy allows the confirmation of the diagnosis, the identification of the position of the ulcer and a laparoscopic repair with effective peritoneal washout. Laparoscopy has also revolutionized the approach to complicated diverticulitis even when intestinal perforation is present. Many other emergency conditions can be effectively managed laparoscopically, including trauma in select hemodynamically-stable patients. We have therefore reviewed the most recent scientific literature on advances in laparoscopy for acute care surgery and trauma in order to demonstrate the current indications and outcomes associated with a laparoscopic approach to the treatment of the most common emergency surgical conditions. | Matteo Mandrioli Kenji Inaba Alice Piccinini Andrea Biscardi Massimo Sartelli Ferdinando Agresta Fausto Catena Roberto Cirocchi Elio Jovine Gregorio Tugnoli Salomone Di Saverio | 2016 | World Journal of Gastroenterology2016，22，2： | 11 |
| 2 | Long-term durable response to lenalidomide in a patient with hepatic epithelioid hemangioendothelioma显示文摘Epithelioid hemangioendothelioma(EH)is a rare tumor arising from the vascular endothelial cells of soft tissue or visceral organs.The most common visceral site is the liver,where it is often involved in a multifocal man-ner known as hepatic EH(HEH).Surgical resection with curative intent represents the gold standard therapy.When surgery is not feasible,or in cases of metastatic disease,no standard medical treatment is currently indicated.In small series,drugs with anti-angiogenic activity(such as bevacizumab,sorafenib,thalidomide,and lenalidomide)have been proposed with promising results.We describe a 73-year-old man with multifocal non-resectable HEH treated with lenalidomide.Disease status was evaluated by abdominal ultrasound and magnetic resonance every four months.The patient was treated for a total of 39 mo with prolonged disease stabilization and,at the time of writing,is still under treatment with a good tolerance profile.During a short period of treatment discontinuation,the disease showed slight progression that immediately resolved after the reintroduction of lenalidomide.Lenalidomide may represent a valid treatment option for HEH due to its anti-angiogenic and antineoplastic activities.This preliminary result merits further study in a large series. | Maria Caterina Pallotti Margherita Nannini Claudio Agostinelli Simona Leoni Valerio Di Scioscio Anna Mandrioli Cristian Lolli Maristella Saponara Stefano Pileri Luigi Bolondi Guido Biasco Maria Abbondanza Pantaleo | 2014 | World Journal of Gastroenterology2014，20，22： | 9 |
| 3 | Stable transformation of a Mamestra brassicae (lepidoptera) cell line with the lepidopteran-derived transposon piggyBac 显示文摘 | Mandrioli M Wimmer EA | 2003 | Insect Biochem Mol Biol2003，33，1： | 1 |
| 4 | DNA methy- lation in insects显示文摘 | FIELD L M LYKO F MANDRIOLI M | 2004 | Insect Mol Biol2004，13，2： | 1 |
| 5 | Separation and analysis of glycyrrhizin,18beta-glycyrrhetic acid and 18alpha-glycyrrhetic acid in liquorice roots by means of capillary zone electrophoresis显示文摘 | Sabbioni C Mandrioli R Ferranti A | 2012 | J Chromatogr A2012，1081，1： | 1 |
| 6 | Chromosomal analysis of repeated DNAs in the rainbow wrasse Coris julis (Pisces, Labridae)显示文摘 | Mandrioli M Colomba M S Vitturi R | 2000 | Genetica2000，108，2： | 1 |
| 7 | Fog droplets:An atmospheric source of secondary biological aerosol particles显示文摘 | Fizzzi S Mandrioli P Perfetto A | 1997 | Atmos Environ1997，31，2： | 1 |
| 8 | charac- terisation of the lymph node reaction in pig post - weaning muhisys- temic wasting syndrome (PMWS) 显示文摘 | Sarli G Mandrioli L Laurenti M | 2001 | Veterinary Immunology and Inununopathology2001，83，12： | 1 |
| 9 | Quantitative Evaluation of Auraptene and Umbelliferone,Chemopreventive Coumarins in Citrus Fruits,by HPLC-UV-FL-MS显示文摘 | Mercolini L Mandrioli R Ferranti A | 2013 | Journal of Agricultural and Food Chemistry2013，61，8： | 1 |
| 10 | Proving Properties of Real-Time Systems Through Logical Specifications and Petri Net Models显示文摘 | Felder M Mandrioli D Morzenti A | 1994 | IEEE Transactions on Software Engineering1994，20，2： | 1 |
| 11 | Immunohistochemical characterisation of the lymph node reaction in pig postweaning multisystemic wasting syndrome (PMWS) 显示文摘 | Sarli G Mandrioli L Laurenti M | 2001 | Vet Immunol Immunopathol2001，83，2： | 1 |
| 12 | 显示文摘 | Mercolini L Mandrioli R Conti M | 2007 | Journal of chromatography B2007，847，2： | 1 |
| 13 | The epidemiology of ALS in Modena,Italy显示文摘 | Mandrioli J Faglioni P Merelli E | 2003 | Neurology2003，60，： | 1 |
| 14 | A sensitive high-performance liquid chromatographic method using electrochemical detection for the analysis of olanzapine and desmethylolanzapine in plasma of schizophrenic patients using a new solid-phase extraction procedure 显示文摘 | Raggi MA Casamenti G Mandrioli R | 2001 | J Chromatogr B:Biomed Sci Appl2001，750，： | 1 |
| 15 | Increasing dietary plant proteins affects growth performance and ammonia excretion gut not digestibility and gut histology in turbot (Psetta rnacima) juveniles 显示文摘 | Bonaldo A Parma L Mandrioli L | 2011 | Aquaculture2011，318，1： | 1 |
| 16 | HPLC analysis of the novel antidepressant duloxetine in human plasma after an original solid phase extraction procedure显示文摘 | Mercolini L Mandrioli R Cazzolla R | 2007 | J of Chromatogra phy B Analyt Technd Bioned Life Sci2007，856，12： | 1 |
| 17 | Liquid chromatographic determination of oxcarbazepine and its metabolites in plasma of epileptic patients after solid - phase extraction显示文摘 | Mandrioli R Ghedini N Albani F | 2003 | J Chromatogr B Analyt Technol Biomed Life Sci2003，783，： | 1 |
| 18 | Apoptosis and proliferative activity in lymph node reaction in post- weaning multi-systemic wasting syndrome (PMWS) 显示文摘 | Mandrioli L Sarli G Panarese S | 2004 | Veterinary Immunology and Immuno-pathology2004，97，： | 1 |
| 19 | DNA methylation in insects 显示文摘 | Field L M Lyko F Mandrioli M | 2004 | Insect Mol Biol2004，13，2： | 1 |
| 20 | Exome sequencing reveals VCP mutations as a cause of familial ALS显示文摘 | Johnson JO Mandrioli J Benatar M | 2010 | New ron2010，68，： | 1 |
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