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| 1 | Accuracy of triage strategies for human papillomavirus DNA-positive women in low-resource settings:A cross-sectional study in China显示文摘Objective: Care HPV is a human papillomavirus(HPV) DNA test for low-resource settings(LRS).This study assesses optimum triage strategies for care HPV-positive women in LRS.Methods: A total of 2,530 Chinese women were concurrently screened for cervical cancer with visual inspection with acetic acid(VIA),liquid-based cytology and HPV testing by physician-and self-collected care HPV,and physician-collected Hybrid Capture 2(HC2).Screen-positive women were referred to colposcopy with biopsy and endocervical curettage as necessary.HPV-positivity was defined as ≥1.0 relative light units/cutoff(RLU/CO) for both care HPV and HC2.Primary physician-HC2,physician-care HPV and self-care HPV and in sequential screening with cytology,VIA,or increased HPV test-positivity performance,stratified by age,were assessed for cervical intraepithelial neoplasia(CIN) grade 2/3 or worse(CIN2/3+) detection.Results: The sensitivities and specificities of primary HPV testing for CIN2+ were: 83.8%,88.1% for physiciancare HPV; 72.1%,88.2% for self-care HPV; and 97.1%,86.0% for HC2.Physician-care HPV test-positive women with VIA triage had a sensitivity of 30.9% for CIN2+ versus 80.9% with cytology triage.Self-care HPV testpositive women with VIA triage was 26.5% versus 66.2% with cytology triage.The sensitivity of HC2 test-positive women with VIA triage was 38.2% versus 92.6% with cytology triage.The sensitivity of physician-care HPV testing for CIN2+ decreased from 83.8% at ≥1.0 RLU/CO to 72.1% at ≥10.00 RLU/CO,while the sensitivity of selfcare HPV testing decreased from 72.1% at ≥1.0 RLU/CO to 32.4% at ≥10.00 RLU/CO; similar trends were seen with age-stratification.Conclusions: VIA and cytology triage improved specificity for CIN2/3 than no triage.Sensitivity with VIA triage was unsuitable for a mass-screening program.VIA provider training might improve this strategy.Cytology triage could be feasible where a high-quality cytology program exists.Triage of HPV test-positive women by increased test positivity cutoff adds another LRS triage option. | Margaret Wang Shangying Hu Shuang Zha o Wenhua Zhang Qinjing Pan Xun Zhang FengChen Jinxiu Han Junfei Ma Jennifer S.Smith Youlin Qiao Caihong Zhou Fanghui Zhao | 2017 | Chinese Journal of Cancer Research2017，29，6： | 6 |
| 2 | Reslizumab in children and adolescents with eosinophilic esophagitis: Results of a double-blind, randomized, placebo-controlled trial显示文摘 | Jonathan M. Spergel Marc E. Rothenberg Margaret H. Collins Glenn T. Furuta Jonathan E. Markowitz George Fuchs Molly A. O’Gorman Juan Pablo Abonia James Young Timothy Henkel H. Jeffrey Wilkins Chris A. Liacouras | 2012 | The Journal of Allergy and Clinical Immunology2012，，： | 3 |
| 3 | Rapid detection of Listeria monocytogenes in food using culture enrichment combined with real-time PCR显示文摘 | Justin O’Grady Margaret Ruttledge Sara Sedano-Balbás Terry J. Smith Thomas Barry Majella Maher | 2008 | Food Microbiology2008，，1： | 2 |
| 4 | Early onset of puberty and early ovarian failure in CYP7B 1 knockout mice显示文摘 | Yoko O Richard L Margaret W eta | 2005 | Proc Natl Acad Sci U S A2005，，8： | 1 |
| 5 | Surveillance for enteric pathogens in a case - control study of acute diarrhea in Western Kenya显示文摘 | Brett E S Elizabeth A O Margaret C K | 2013 | Transactions of the Royal Society of Trop- ical Medicine and Hygiene2013，107，2： | 1 |
| 6 | Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary cili- ary dyskinesia 显示文摘 | Marcus PK Heymut O Margaret WL | 2007 | Circulation2007，115，22： | 1 |
| 7 | A simple more general hoxplot method for identifying outliers显示文摘 | Nell C S Margaret A O Rohiah A | 2004 | Computational Sta tistics & Data Analysis2004，47，1： | 1 |
| 8 | DEATH IN THE OPERATING ROOM: AN ANALYSIS OF A MULTI-CENTER EXPERIENCE显示文摘 | David B. Hoyt Eileen M. Bulger M. Margaret Knudson John Morris Ralph lerardi Harvey J. Sugerman Steven R. Shackford Jeffery Landercasper Robert J. Winchell Gregory Jurkovich Susan C. Coffey Michael Chang Keith F. O?Malley James Lowry Gino T. Trevisani Tho | 1994 | The Journal of Trauma: Injury Infection and Critical Care1994，，3： | 1 |
| 9 | The Medical Student Stress Profile:a tool for stress audit in medical training显示文摘 | Margaret O'Rourke Sean Hammond Siun O'Flynn | 2010 | Medical Education2010，，44： | 1 |
| 10 | Examining methodological details of neighborhood observations and the relationship to health:A literature review 显示文摘 | Nicole SM Margaret O Wayne G | 2010 | Social Science Medicine2010，70，： | 1 |
| 11 | Stress relaxation of springs显示文摘 | Margaret O | 1988 | Wire Industry1988，，12： | 1 |
| 12 | Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response显示文摘 | Margaret J Leckie Anneke ten Brinke Jamey Khan Zuzana Diamant Brian J O’Connor Christine M Walls Ashwini K Mathur Hugh C Cowley K Fan Chung Ratko Djukanovic Trevor T Hansel Stephen T Holgate Peter J Sterk Peter J Barnes | 2000 | The Lancet2000，，9248： | 1 |
| 13 | The MFMU Cesarean Registry: Factors affecting the success of trial of labor after previous cesarean delivery显示文摘 | Mark B. Landon Sharon Leindecker Catherine Y. Spong John C. Hauth Steven Bloom Michael W. Varner Atef H. Moawad Steve N. Caritis Margaret Harper Ronald J. Wapner Yoram Sorokin Menachem Miodovnik Marshall Carpenter Alan M. Peaceman Mary Jo O’Sullivan Baha | 2005 | American Journal of Obstetrics and Gynecology2005，，3： | 1 |
| 14 | Mod- elling of surface acoustie wave strain sensors using coupling-of- modes analysis显示文摘 | Brian Me Cormack Dermot Geraghty Margaret O'Mahony | 2005 | Eurosensors XIX2005，，： | 1 |
| 15 | Mod- eling of Surface Acoustic Wave Strain Sensors Using Coupling-of- Modes Analysis 显示文摘 | Brian Mc Cormack Dermot Geraghty Margaret O' Mahony | 2011 | IEEE Transaction on Ultrasonics Fen-oelec- trics and Frequency Control2011，58，11： | 1 |
| 16 | Endophytic fungi in indigenous Australasian grasses associaied with toxicity to livestock显示文摘 | CHRISTOPHER O M MARGARET E D | 1998 | Applied and Environmental Microbiology1998，64，： | 1 |
| 17 | Schwann cell but not olfactory ensheathing glia transplants improve hindlimb locomotor performance in the moderately contused adult rat thoracic spinal cord显示文摘 | Toshihiro T Martin O Margaret L B | 2002 | Neuroscience2002，，22： | 1 |
| 18 | Analysis of the Shear Strength of Recycle Aggregates 显示文摘 | Mahony O Margaret M | 1997 | Materials and Structures1997，204，30： | 1 |
| 19 | The use of C oban<sup>TM</sup> compression bandage following below‐knee free‐flap surgery显示文摘 | Toby O Smith Sarah Hazelden Laura Parker Bhavana Jha Margaret Youatt Richard Haywood | 2012 | Int J Nurs Pract2012，，6： | 1 |
| 20 | Integrating evidence-based practice in nurse practice education显示文摘 | MARGARET A ELIZABETH A DIANE O T | 2004 | Clin Pract Guildlines2004，16，12： | 1 |
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