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| 1 | VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab显示文摘AIM:To gain mechanistic insights into the role played by epidermal growth factor receptor (EGFR) in the regulation of vascular endothelial growth factors (VEGFs) in colorectal cancer (CRC). METHODS:The impact of high-level expression of the growth factor receptors EGFR and VEGF receptor (VEGFR)3 and the VEGFR3 ligands VEGF-C and VEGF-D on disease progression and prognosis in human CRC was investigated in 108 patients using immunohistochemistry. Furthermore, the expression of the lymphangiogenic factors in response to the modulation of EGFR signalling by the EGFR-targeted monoclonal antibody cetuximab was investigated at the mRNA and protein level in human SW480 and SW620 CRC cell lines and a mouse xenograft model. RESULTS: Human CRC specimens and cell lines displayed EGFR, VEGF-C and VEGF-D expression with varying intensities. VEGF-C expression was associated with histological grade. Strong expression of VEGF-D was significantly associated with lymph node metastases and linked to a trend for decreased survival in lymph node-positive patients. EGFR blockade with cetuximab resulted in a significant decrease of VEGF-D expression in vitro and in vivo. CONCLUSION:In conclusion, the expression of VEGF-D in colorectal tumours is significantly associated with lymphatic involvement in CRC patients and such expression might be blocked effectively by cetuximab. | Markus Moehler Christian Frings Annett Mueller Ines Gockel Carl C Schimanski Stefan Biesterfeld Institute of Pathology Johannes Gutenberg University Mainz 55101 Germany Peter R Galle Martin H Holtmann | 2008 | World Journal of Gastroenterology2008,14,26: | 15 |
| 2 | Watt-scale super-octave mid-infrared intrapulse difference frequency generation显示文摘The development of high-power,broadband sources of coherent mid-infrared radiation is currently the subject of intense research that is driven by a substantial number of existing and continuously emerging applications in medical diagnostics,spectroscopy,microscopy,and fundamental science.One of the major,long-standing challenges in improving the performance of these applications has been the construction of compact,broadband mid-infrared radiation sources,which unify the properties of high brightness and spatial and temporal coherence.Due to the lack of such radiation sources,several emerging applications can be addressed only with infrared(IR)-beamlines in largescale synchrotron facilities,which are limited regarding user access and only partially fulfill these properties.Here,we present a table-top,broadband,coherent mid-infrared light source that provides brightness at an unprecedented level that supersedes that of synchrotrons in the wavelength range between 3.7 and 18μm by several orders of magnitude.This result is enabled by a high-power,few-cycle Tm-doped fiber laser system,which is employed as a pump at 1.9μm wavelength for intrapulse difference frequency generation(IPDFG).IPDFG intrinsically ensures the formation of carrierenvelope-phase stable pulses,which provide ideal prerequisites for state-of-the-art spectroscopy and microscopy. | Christian Gaida Martin Gebhardt Tobias Heuermann Fabian Stutzki Cesar Jauregui Jose Antonio-Lopez Axel Schulzgen Rodrigo Amezcua-Correa Andreas Tunnermann Ioachim Pupeza Jens Limpert | 2018 | Light(Science & Applications)2018,7,1: | 8 |
| 3 | Innovative immunohistochemistry identifies MMP-9 expressing macrophages at the invasive front of murine HCC显示文摘AIM:To investigate the proteolytic contribution of tumor-associated macrophages(TAM)in tumor invasion,we analyzed whether TAM at the invasive front of small HCC in Abcb4-/--mice show an enhanced expression of MMP-9. METHODS:Liver cryosections of the hepatocellular carcinoma(HCC)invasive front from 12 mo old Abcb4-/--mice were stained for collagen typeⅠand MMP-9 using Alexa488 and Alexa568 labeled secondary antibodies.Afterwards,the Alexa568 dye was bleached and the macrophage marker F4/80 was visualized using Alexa568 labeled secondary antibodies.Finally, photographs of the invasive tumor front were digitally overlaid and analyzed. RESULTS:After complete bleaching of the primary dye,specific fluorescence staining of a third antigen, here F4/80,was successfully performed on the same histological section.With this method,we were able to identify conglomerates of matrix metalloproteinase (MMP-9)expressing macrophages within the tumor capsule of HCC. CONCLUSION:MMP-9 expressing macrophages are involved in matrix remodelling at the invasive tumor front of HCC.The described staining protocol provides a simple yet powerful extension of conventional immuno-histochemistry,facilitating visualization of at least three different antigens plus nuclei in one single histological section. | Martin Roderfeld Timo Rath Frank Lammert Christian Dierkes Jürgen Graf Elke Roeb | 2010 | World Journal of Hepatology2010,2,5: | 6 |
| 4 | 多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识显示文摘新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。 | 王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca Neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki Noble Laurent Zieleskiewicz Pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca Karim Bendjelid Belaid Bouhemad Pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano Peiman Nazerian Bret P.Nelson Aleksandar N.Neskovic Ramon Nogue Adi Osman JoséPazeli Elmo Pereira-Junior Tomislav Petrovic Emanuele Pivetta Jan Poelaert Susanna Price Gregor Prosen Shalim Rodriguez Philippe Rola Colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi | 2021 | 中国呼吸与危重监护杂志2021,20,2: | 5 |
| 5 | Towards efficient data exchange and sharing for big-data driven materials science:metadata and data formats显示文摘With big-data driven materials research,the new paradigm of materials science,sharing and wide accessibility of data are becoming crucial aspects.Obviously,a prerequisite for data exchange and big-data analytics is standardization,which means using consistent and unique conventions for,e.g.,units,zero base lines,and file formats.There are two main strategies to achieve this goal.One accepts the heterogeneous nature of the community,which comprises scientists from physics,chemistry,bio-physics,and materials science,by complying with the diverse ecosystem of computer codes and thus develops“converters”for the input and output files of all important codes.These converters then translate the data of each code into a standardized,codeindependent format.The other strategy is to provide standardized open libraries that code developers can adopt for shaping their inputs,outputs,and restart files,directly into the same code-independent format.In this perspective paper,we present both strategies and argue that they can and should be regarded as complementary,if not even synergetic.The represented appropriate format and conventions were agreed upon by two teams,the Electronic Structure Library(ESL)of the European Center for Atomic and Molecular Computations(CECAM)and the NOvel MAterials Discovery(NOMAD)Laboratory,a European Centre of Excellence(CoE).A key element of this work is the definition of hierarchical metadata describing state-of-the-art electronic-structure calculations. | Luca M.Ghiringhelli Christian Carbogno Sergey Levchenko Fawzi Mohamed Georg Huhs Martin Luders Micael Oliveira Matthias Scheffler | 2017 | npj Computational Materials2017,,1: | 5 |
| 6 | Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells显示文摘 | Arnold Isabelle C Dehzad Nina Reuter Sebastian Martin Helen Becher Burkhard Taube Christian Müller Anne | 2011 | Journal of Clinical Investigation2011,,8: | 4 |
| 7 | Hybrid multi-chip assembly of optical communication engines by in situ 3D nanolithography显示文摘Three-dimensional(3D)nano-printing of freeform optical waveguides,also referred to as photonic wire bonding,allows for efficient coupling between photonic chips and can greatly simplify optical system assembly.As a key advantage,the shape and the trajectory of photonic wire bonds can be adapted to the mode-field profiles and the positions of the chips,thereby offering an attractive alternative to conventional optical assembly techniques that rely on technically complex and costly high-precision alignment.However,while the fundamental advantages of the photonic wire bonding concept have been shown in proof-of-concept experiments,it has so far been unclear whether the technique can also be leveraged for practically relevant use cases with stringent reproducibility and reliability requirements.In this paper,we demonstrate optical communication engines that rely on photonic wire bonding for connecting arrays of silicon photonic modulators to InP lasers and single-mode fibres.In a first experiment,we show an eight-channel transmitter offering an aggregate line rate of 448 Gbit/s by low-complexity intensity modulation.A second experiment is dedicated to a four-channel coherent transmitter,operating at a net data rate of 732.7 Gbit/s-a record for coherent silicon photonic transmitters with co-packaged lasers.Using dedicated test chips,we further demonstrate automated mass production of photonic wire bonds with insertion losses of(0.7±0.15)dB,and we show their resilience in environmental-stability tests and at high optical power.These results might form the basis for simplified assembly of advanced photonic multi-chip systems that combine the distinct advantages of different integration platforms. | Matthias Blaicher Muhammad Rodlin Billah Juned Kemal Tobias Hoose Pablo Marin-Palomo Andreas Hofmann Yasar Kutuvantavida Clemens Kieninger Philipp-Immanuel Dietrich Matthias Lauermann Stefan Wolf Ute Troppenz Martin Moehrle Florian Merget Sebastian Skacel Jeremy Witzens Sebastian Randel Wolfgang Freude Christian Koos | 2020 | Light(Science & Applications)2020,9,1: | 4 |
| 8 | Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA显示文摘 | Katrin Panzitt Marisa M.O. Tschernatsch Christian Guelly Tarek Moustafa Martin Stradner Heimo M. Strohmaier Charles R. Buck Helmut Denk Renée Schroeder Michael Trauner Kurt Zatloukal | 2007 | Gastroenterology2007,,1: | 4 |
| 9 | Explaining the influence of dopant concentration and excitation power density on the luminescence and brightness of β-NaYF4:Yb^3+,Er^3+ nanoparticles:Measurements and simulations显示文摘We assessed the influence of Yb^3+ and Er34 dopant concentration on the relative spectral distribution, quantum yield (Фuc), and decay kinetics of the upconversion luminescence (UCL) and particle brightness (BUC) for similarly sized (33 nm) oleate-capped p-NaYF4:Yb3t,Er^3+ upconversion (UC) nanoparticles (UCNPs) in toluene at broadly varied excitation power densities (F). This included an Yb^3+ series where the Yb^3+ concentration was varied between 11%—21% for a constant Er^3+ concentration of 3%, and an Er^3+ series, where the Er^3+ concentration was varied between 1%-4% for a constant Yb^3+ concentration of 14%. The results were fitted with a coupled rate equation model utilizing the UCL data and decay kinetics of the green and red Er34 emission and the Yb34 luminescence at 980 nm. An increasing Yb34 concentration favors a pronounced triphotonic population of 4F9/2 at high P by an enhanced back energy transfer (BET) from the 4G11/2 level. Simultaneously, the Yb^3+-controlled UCNPs absorption cross section overcompensates for the reduction in Фuc with increasing Yb^3+ concentration at high P, resulting in an increase in Sue. Additionally, our results show that an increase in Yb34 and a decrease in Er^3+ concentration enhance the color tuning range by P. These findings will pave the road to a deeper understanding of the energy transfer processes and their contribution to efficient UCL, as well as still debated trends in green-to-red intensity ratios of UCNPs at different P. | Martin Kaiser Christian Wurth Marco Kraft Tero Soukka Ute Resch-Genger | 2019 | Nano Research2019,12,8: | 3 |
| 10 | Sludge thickening in a wastewater treatment plant using a modified hydrocyclone显示文摘The main application of hydrocyclones in most industry sectors is the separation of particles from liquids.For thickening,however,the separation properties of the cyclone should be adjustable,which requires a different operating mode.Therefore,we investigated an add-on thickening module,consisting of a conical plug and a secondary vortex finder in the underflow of the hydrocyclone.Laboratory scale experiments are carried out to investigate the function of the concept of annular gap modification by the use of the thickening module.In the second step,we transferred this concept to industrial scale for field tests at a municipal wastewater treatment plant.In the field tests,geometrical properties(annular gap modification)and operational parameters(volume flow rate,sludge type)were investigated.The results show that thickening in terms of increasing the total solids content of sludge is possible with the modified hydrocyclone.In the field tests,a thickening factor(total solids content of thickened sludge related to feed sludge)of 1.31(average)was reached for digested sludge.Hence,a hydrocyclone could be a promising addition in wastewater treatment plants for dewatering of sludge. | Thomas Senfter Lukas Fritsch Manuel Berger Tobias Kofler Christian Mayerl Martin Pillei Michael Kraxner | 2021 | Carbon Resources Conversion2021,4,1: | 3 |
| 11 | 活体牙周膜有限元仿真的可行性研究显示文摘目的通过现代有限元方法研究牙周膜上的静平衡应力状态。方法提出了两种用于分析牙周膜应力状态的有限元方法,把牙周膜看做是整个下颌模型的一部分,通过有限元方法来处理仿真的牙齿并加载,来研究牙周膜对牙周组织的应力应变分布的作用,计算得到的静平衡应力和牙齿根吸收状态进行比较。结果牙周膜的最大应力发生在接近最高点位置,在中跟位置附近存在局部最大应力,而牙周膜顶点区域的应力要大于牙周膜中根附近的局部最大应力。齿槽顶部的舌侧牙周膜部位可以发现静平衡应力。静平衡应力是和位置有关的,有静平衡应力的部位就会发生牙根吸收。结论人类切牙和单根前臼齿一样,植入物会导致其牙周膜顶点附近静平衡应力的增长,这一点同之前的发现相一致。人类切牙根吸收经常作用于牙周膜的顶点部位。 | Ansgar Hohmann Cornelia Kober Thomas Radtke Philippe Young Martin Geiger Andrew Boryor Christian Sander Franz Gunter Sander | 2008 | 医用生物力学2008,23,1: | 3 |
| 12 | Investigation on aerodynamic force effect of vacuum plumes using pressure-sensitive paint technique and CFD-DSMC solution显示文摘Pressure-sensitive paint(PSP) technique was employed to experimentally investigate the aerodynamic force effect of vacuum plume in this study. The characterization and comparison for two types of PSP were firstly conducted in an air pressure range from0.05 to 5000 Pa. The PSPs were prepared using PtTFPP as the active dye and different binders, i.e., polymer-ceramic(PC) and poly(1-trimethylsilyl-1-propyne) [poly(TMSP)]. The static calibrations showed that PtTFPP/poly(TMSP) had a higher pressure sensitivity and a lower temperature dependency compared to PtTFPP/PC in this pressure range. The pressure distributions of a single and two interacting plumes impinging onto a flat plate model were measured using PSP technique. The experimental data were compared to numerical solutions that combined both the computed fluid dynamics(CFD) and direct simulation Monte Carlo(DSMC) methods. Remarkable agreements were achieved, demonstrating the feasibility and accuracy of the numerical approach.Finally, the aerodynamic force effect of interacting plumes at different separation distances was investigated numerically. | WU Jing BITTER Martin CAI GuoBiao HE BiJiao KAEHLER Christian | 2017 | Science China(Technological Sciences)2017,60,7: | 3 |
| 13 | Zero-dimensional polariton laser in a subwavelength grating-based vertical microcavity显示文摘Semiconductor exciton–polaritons in planar microcavities form coherent two-dimensional condensates in non-equilibrium.However,the coupling of multiple lower-dimensional polariton quantum systems,which are critical for polaritonic quantum device applications and novel cavity-lattice physics,has been limited in conventional cavity structures.Here,we demonstrate full non-destructive confinement of polaritons using a hybrid cavity composed of a single-layer subwavelength grating mirror and a distributed Bragg reflector.Single-mode polariton lasing was observed at a chosen polarization.The incorporation of a designable slab mirror in a conventional vertical cavity,when operating in the strong-coupling regime,enables the confinement,control and coupling of polariton gasses in a scalable fashion.This approach may open the door to experimental implementations of polariton-based quantum photonic devices and coupled cavity quantum electrodynamic systems. | Bo Zhang Zhaorong Wang Sebastian Brodbeck Christian Schneider Martin Kamp Sven Hofling Hui Deng | 2014 | Light(Science & Applications)2014,3,1: | 3 |
| 14 | Endoscopic dilation of complete oesophageal obstructionswith a combined antegrade-retrograde rendezvoustechnique显示文摘AIM: To investigate the combined antegraderetrograde endoscopic rendezvous technique for complete oesophageal obstruction and the swallowing outcome.METHODS: This single-centre case series includes consecutive patients who were unable to swallow due to complete oesophageal obstruction and underwent combined antegrade-retrograde endoscopic dilation(CARD) within the last 10 years. The patients' demographic characteristics, clinical parameters, endoscopic therapy, adverse events, and outcomes were obtained retrospectively. Technical success was defined as effective restoration of oesophageal patency. Swallowing success was defined as either percutaneous endoscopic gastrostomy(PEG)-tube independency and/or relevant improvement of oral food intake, as assessed by the functional oral intake scale(FOIS)(≥ level 3).RESULTS: The cohort consisted of six patients [five males; mean age 71 years(range, 54-74)]. All but one patient had undergone radiotherapy for head and neck or oesophageal cancer. Technical success was achieved in five out of six patients. After discharge, repeated dilations were performed in all five patients. During follow-up(median 27 mo, range, 2-115), three patients remained PEG-tube dependent. Three of four patients achieved relevant improvement of swallowing(two patients: FOIS 6, one patient: FOIS 7). One patient developed mediastinal emphysema following CARD, without a need for surgery.CONCLUSION: The CARD technique is safe and a viable alternative to high-risk blind antegrade dilation in patients with complete proximal oesophageal obstruction. Although only half of the patients remained PEG-tube independent, the majority improved their ability to swallow. | Reto Bertolini Christa Meyenberger Paul Martin Putora Franziska Albrecht Martina Anja Broglie Sandro J Stoeckli Michael Christian Sulz | 2016 | World Journal of Gastroenterology2016,22,7: | 3 |
| 15 | Hydroxyethylstarch revisited for acute brain injury treatment显示文摘Infusion of the colloid hydroxyethylstarch has been used for volume substitution to maintain hemodynamics and microcirculation after e.g., severe blood loss.In the last decade it was revealed that hydroxyethylstarch can aggravate acute kidney injury, especially in septic patients.Because of the serious risk for critically ill patients, the administration of hydroxyethylstarch was restricted for clinical use.Animal studies and recently published in vitro experiments showed that hydroxyethylstarch might exert protective effects on the blood-brain barrier.Since the prevention of blood-brain barrier disruption was shown to go along with the reduction of brain damage after several kinds of insults, we revisit the topic hydroxyethylstarch and discuss a possible niche for the application of hydroxyethylstarch in acute brain injury treatment. | Martin A.Schick Malgorzata Burek Carola Y.Forster Michiaki Nagai Christian Wunder Winfried Neuhaus | 2021 | Neural Regeneration Research2021,16,7: | 2 |
| 16 | Therapeutic efficacy and effects of artemisinin-based combination treatments on uncomplicated Plasmodium falciparum malaria-associated anaemia in Nigerian children during seven years of adoption as first-line treatments显示文摘Background:Artemisinin-based combination treatments(ACTs)are the first-line treatments of uncomplicated Plasmodium falciparum malaria in many endemic areas but there are few evaluation of their efficacy in anaemic malarious children.Methods:Therapeutic efficacy of 3-day regimens of artesunate-amodiaquine and artemether-lumefantrine was evaluated in 437 anaemic and 909 non-anaemic malarious children following treatment during a seven-year period(2008-2014).Patterns of temporal changes in haematocrit were classified based on haematocrit values<30%and≥30%.Kinetics of the disposition of the deficit in haematocrit from 30%following treatment were evaluated using a non-compartment model.Results:PCR-corrected parasitological efficacy 28 days after start of treatment was significantly higher in artesunateamodiaquine-compared to artemether-lumefantrine-treated children[97%(95%CI:92.8-100)versus 96.4%(95%CI:91.3-99.4),P=0.02],but it was similar in non-anaemic and anaemic children.Fall in haematocrit/1000 asexual parasites cleared from peripheral blood was significantly greater at lower compared to higher parasitaemias(P<0.0001),and in non-anaemic compared to anaemic children(P=0.007).In anaemic children at presentation,mean anaemia recovery time(AnRT)was 15.4 days(95%CI:13.3-17.4)and it did not change over the years.Declines in haematocrit deficits from 30%were monoexponential with mean estimated half-time of 1.4 days(95%CI:1.2-1.6).Anaemia half-time(t_(1/2anaemia))correlated positively with AnRT in the same patients(r=0.69,P<0.0001).Bland-Altman analysis of 10 multiples of t_(1/2anaemia) and AnRT showed narrow limit of agreement with insignificant bias(P=0.07)suggesting both can be used interchangeably in the same patients.Conclusions:Artesunate-amodiaquine and artemether-lumefantrine remain efficacious treatments of uncomplicated P.falciparum infections in non-anaemic and anaemic Nigerian children in the last 7 years of adoption as first-line treatments.These ACTs may also conserve haematocrit at high parasitaemias and in anaemic children.Trials registration:Pan African Clinical Trial Registry PACTR201508001188143,3 July 2015;PACTR201510001189370,3 July 2015;PACTR201508001191898,7 July 2015 and PACTR201508001193368,8 July 2015. | Akintunde Sowunmi Kazeem Akano Godwin Ntadom Adejumoke I.Ayede Folasade O.Ibironke Temitope Aderoyeje Elsie O.Adewoye Bayo Fatunmbi Stephen Oguche Henrietta U.Okafor Ismaila Watila Martin Meremikwu Philip Agomo William Ogala Chimere Agomo Onikepe A.Folarin Grace O.Gbotosho Christian T.Happi | 2017 | Infectious Diseases of Poverty2017,6,1: | 2 |
| 17 | National Forest Inventories capture the multifunctionality of managed forests in Germany显示文摘Background:Forests perform various important ecosystem functions that contribute to ecosystem services.In many parts of the world,forest management has shifted from a focus on timber production to multi-purpose forestry,combining timber production with the supply of other forest ecosystem services.However,it is unclear which forest types provide which ecosystem services and to what extent forests primarily managed for timber already supply multiple ecosystem services.Based on a comprehensive dataset collected across 150 forest plots in three regions differing in management intensity and species composition,we develop models to predict the potential supply of 13 ecosystem services.We use those models to assess the level of multifunctionality of managed forests at the national level using national forest inventory data.Results:Looking at the potential supply of ecosystem services,we found trade-offs(e.g.between both bark beetle control or dung decomposition and both productivity or soil carbon stocks)as well as synergies(e.g.for temperature regulation,carbon storage and culturally interesting plants)across the 53 most dominant forest types in Germany.No single forest type provided all ecosystem services equally.Some ecosystem services showed comparable levels across forest types(e.g.decomposition or richness of saprotrophs),while others varied strongly,depending on forest structural attributes(e.g.phosphorous availability or cover of edible plants)or tree species composition(e.g.potential nitrification activity).Variability in potential supply of ecosystem services was only to a lesser extent driven by environmental conditions.However,the geographic variation in ecosystem function supply across Germany was closely linked with the distribution of main tree species.Conclusions:Our results show that forest multifunctionality is limited to subsets of ecosystem services.The importance of tree species composition highlights that a lack of multifunctionality at the stand level can be compensated by managing forests at the landscape level,when stands of complementary forest types are combined.These results imply that multi-purpose forestry should be based on a variety of forest types requiring coordinated planning across larger spatial scales. | Nadja K.Simons María R.Felipe-Lucia Peter Schall Christian Ammer Jürgen Bauhus Nico Blüthgen Steffen Boch François Buscot Markus Fischer Kezia Goldmann Martin M.Gossner Falk Hänsel Kirsten Jung Peter Manning Thomas Nauss Yvonne Oelmann Rodica Pena Andrea Polle Swen C.Renner Michael Schloter Ingo Schöning Ernst-Detlef Schulze Emily F.Solly Elisabeth Sorkau Barbara Stempfhuber Tesfaye Wubet Jörg Müller Sebastian Seibold Wolfgang W.Weisser | 2021 | Forest Ecosystems2021,8,1: | 2 |
| 18 | Treatment of small coronary arteries with a paclitaxel-coated balloon catheter显示文摘 | Martin Unverdorben Franz X. Kleber Hubertus Heuer Hans-Reiner Figulla Christian Vallbracht Matthias Leschke Bodo Cremers Stefan Hardt Michael Buerke Hanns Ackermann Michael Boxberger Ralf Degenhardt Bruno Scheller | 2010 | Clinical Research in Cardiology2010,,3: | 2 |
| 19 | 反思金融深化:新兴市场的稳定与发展显示文摘有深度和流动性良好的金融系统,加上有丰富的金融工具可抵御金融冲击,还可以增加一国金融的稳定性。但是金融发展或许存在一个边界,越过此边界进一步发展其收益或将下降。本文通过研究新兴市场发现:一、大部分新兴市场金融进一步发展仍然对经济的增长和稳定有利。二、金融发展对经济增长的促进作用是倒U型的,在越过高点之后金融深化对要素生产率的促进作用将下降。三、如果金融发展过快,快速深化的金融产业可能引发经济和金融动荡。四、提升金融稳定与金融发展之间没有太大冲突,更好的金融监管有助于提升金融稳定,促进金融发展。五、发展金融机构或金融市场不存在通用的顺序,尽管前者对经济的作用在下降而后者在上升。 | IMF课题组 Ratna Sahay Martin Cihak Papa N’Diaye Adolfo Barajas Ran Bi Diana Ayala Yuan Gao Annette Kyobe Lam Nguyen Christian Saborowski Katsiaryna Svirydzenka Seyed Reza Yousefi 胡妍斌 王辰 | 2015 | 新金融2015,0,10: | 2 |
| 20 | Geographic routing in city scenarios显示文摘 | Christian Lochert Martin Mauve Holger Fü?ler Hannes Hartenstein | 2005 | ACM SIGMOBILE Mobile Computing and Communications Review2005,,1: | 2 |