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| 1 | Extragastric manifestations of Helicobacter pylori infection: Possible role of bacterium in liver and pancreas diseases显示文摘Helicobacter pylori(H. pylori) is an ancient microorganism that has co-evolved with humans for over 60000 years. This bacterium typically colonizes the human stomach and it is currently recognized as the most common infectious pathogen of the gastroduodenal tract. Although its chronic infection is associated with gastritis, peptic ulcer, dysplasia, neoplasia, MALT lymphoma and gastric adenocarcinoma, it has been suggested the possible association of H. pylori infection with several extragastric effects including hepatobiliary and pancreatic diseases. Since a microorganism resembling H. pylori was detected in samples from patients with hepatobiliary disorders, several reports have been discussed the possible role of bacteria in hepatic diseases as hepatocellular carcinoma, cirrhosis and hepatic encephalopathy, nonalcoholic fatty liver disease and fibrosis. Additionally, studies have reported the possible association between H. pylori infection and pancreatic diseases, especially because it has been suggested that this infection could change the pancreatic physiology. Some of them have related a possible association between the microorganism and pancreatic cancer. H. pylori infection has also been suggested to play a role in the acute and chronic pancreatitis pathogenesis, autoimmune pancreatitis, diabetes mellitus and metabolic syndrome. Considering that association of H. pylori to liver and pancreas diseases needs further clarification, our work offers a review about the results of some investigations related to the potential pathogenicity of H. pylori in these extragastric diseases. | Elizabeth MA Rabelo-Goncalves Bruna M Roesler Jose MR Zeitune | 2015 | World Journal of Hepatology2015，7，30： | 16 |
| 2 | Keratinocyte carcinoma显示文摘 | Albert MR Weinstock MA | 2003 | CA Cancer J Clin2003，53，： | 1 |
| 3 | Characterization of GATA3 mutations in the hypoparathyroidism,deafness,and renal dysplasia (HDR) syndrome显示文摘 | Nesbit MA Bowl MR Harding B | 2004 | J Biol Chem2004，279，22： | 1 |
| 4 | Asthma analysis of sudden deaths and ventilatory arrests in hospital 显示文摘 | Hetzel MR Clark TJ Braithwaite MA | 1977 | Br Med J1977，1，： | 1 |
| 5 | Combined use of α- adrenergic and muscarinic antagonists for the treatment of voiding dysfunction显示文摘 | Ruggieri MR Braverman AS Pontari MA | 2005 | J Urol2005，174，5： | 1 |
| 6 | The most effective Gold nanorod size for plasmonic photothermal therapy: theory and in vitro experiments显示文摘 | Mackey MA Ali MR Austin LA | 2014 | J Phys Chem B2014，118，： | 1 |
| 7 | Primary ciliary dyskinesia: improving the diagnostic approach显示文摘 | Leigh MW Zariwala MA Knowles MR | 2009 | CUff Opin Pediatr2009，21，3： | 1 |
| 8 | Primary medication non-adherence:analysis of 195,930electronic prescriptions显示文摘 | Fischer MA Stedman MR Lii J | 2010 | Journal of General Internal Medicine2010，25，4： | 1 |
| 9 | Food poisoning and Staphylococcus aureus enterotoxins 显示文摘 | Argudin MA Mendoza MC Rodicio MR | 2010 | Toxins2010，2，7： | 1 |
| 10 | The M2 muscarinic receptor mediates in vitro bladder contractions from patients with neurogenic bladder dysfunction显示文摘 | Pontari MA Braverman AS Ruggieri MR | 2004 | Am J Physiol Regul Integr Comp Physiol2004，286，5： | 1 |
| 11 | Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphlsms in lung cancer risk 显示文摘 | Spitz MR Duphorne CM Detry MA | 2000 | Cancer Epidemiol Biomarkers Prev2000，9，10： | 1 |
| 12 | Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells 显示文摘 | Huang C Ma WY Young MR Colburn N Dong Z | 1998 | Proc NatlAcad Sci USA1998，95，1： | 1 |
| 13 | Conversion ofAconitine to Lipoaconitine by Human Intestinal Bacteriaand theirAntinociceptive Effectsin Mice显示文摘 | Kawata Y Ma CM Meselhy MR | 1999 | Tradit Med1999，16，1： | 1 |
| 14 | Occult hypoglycemia caused by hemodialysis显示文摘 | Jackson MA Holland MR Nicholas J | | 0，，14： | 1 |
| 15 | Complications of surgery for subfoveal choroidal neovascularization显示文摘 | Fleckner MR Hochman MA Buzney SM | | 0，，： | 1 |
| 16 | ImmunoCyt and cytokeratin,20 immunocytochemistry as adjunct markers for urine cytologic detection of bladder cancer:a prospective study显示文摘 | Li HX Li M Li CL Ma JH Wang MR Rao J | | 0，，： | 1 |
| 17 | Diagnosis of gastrointestinal tract Lesions by endoscopic ultrasound-guided fine-needle aspiration biopsy显示文摘 | Vander Noot MR 3rd Eloubeidi MA Chen VK | 2004 | Cancer2004，102，3： | 1 |
| 18 | Myocardial structural changes in long-term human severe sepsis/ septic shock may be responsible for cardiac dysfunction显示文摘 | Rossi MA Celes MR Prado CM | 2007 | Shock2007，27，1： | 1 |
| 19 | Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes显示文摘 | Benakanakere MR Li Q Eskan MA | 2009 | J Biol Chem2009，284，23： | 1 |
| 20 | Isolation and characterization of Cryptococcus neoformans spores reveal a critical role for capsule biosynthesis genes in spore biogenesis显示文摘 | Botts MR Giles SS Gates MA | 2009 | Eukaryot Cell2009，8，4： | 1 |
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