|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 影响颅内动脉瘤破裂风险的患者个体特征(英文)显示文摘BACKGROUND AND PURPOSE Knowledge about risk factors contributes to understanding the pathophysiological mechanisms that cause intracranial aneurysm rupture and helps to develop possible treatment strategies.We aimed to study lifestyle and personal characteristics as risk factors for the rupture of intracranial aneurysms.METHODS We performed a case-control study with 250 patients with an aneurysmal subarachnoid hemorrhage and 206 patients with an unruptured intracranial aneurysm.All patients with an aneurysmal subarachnoid hemorrhage and patients with a unruptured intracranial aneurysm were asked to fill in a structured questionnaire about their lifestyle and medical history.For patients with an unruptured intracranial aneurysm,we also collected data on the indication for imaging.With logistic regression analysis,we identified independent risk factors for aneurysmal rupture.RESULTS Reasons for imaging in patients with an unruptured intracranial aneurysm were atherosclerotic disease(23%),positive family history(18%),headache(8%),preventive screening(3%),and other(46%).Factors that increased risk for aneurysmal rupture were smoking(odds ratio,1.9;95% confidence interval,1.2-3.0) and migraine(2.4;1.1-5.1);hypercholesterolemia decreased this risk(0.4;0.2-1.0),whereas a history of hypertension did not independently influence the risk.CONCLUSIONS Smoking,migraine and,inversely,hypercholesterolemia are independent risk factors for aneurysmal rupture.Data from the questionnaire are insufficient to conclude whether hypercholesterolemia or its treatment with statins exerts a risk-reducing effect.The pathophysiological mechanisms through which smoking and migraine increase the risk of aneurysmal rupture should be investigated in further studies.Although a history of hypertension does not increase risk of rupture,a sudden rise in blood pressure might still trigger aneurysmal rupture. | Vlak MH Rinkel GJ Greebe P Algra A | 2013 | 中华神经外科疾病研究杂志2013，12，3： | 17 |
| 2 | Effect of vitamin E on oxidative stress status in small intestine of diabetic rat显示文摘AIM:To investigate the effect of vitamin E on oxidative stress status in the small intestine of diabetic rats. METHODS:Twenty-four male Wistar rats were randomly divided into three groups:Control (C),non-treated diabetic (NTD) and vitamin E-treated diabetic (VETD) groups. The increases in lipid peroxidation,protein oxidation and superoxide dismutase (SOD) in these three groups was compared after 6 wk. RESULTS:There was no significant difference in catalase activity between NTD and control rats. Compared to NTD rats,the treatment with vitamin E significantly decreased lipid peroxidation and protein oxidation,and also increased catalase activity and SOD. CONCLUSION:The results revealed the occurrence of oxidative stress in the small intestine of diabetic rats. Vitamin E,as an antioxidant,attenuates lipid peroxidation and protein oxidation,and increases antioxidant defense mechanism. | A Shirpoor MH Khadem Ansari S Salami F Ghaderi Pakdel Y Rasmi | 2007 | World Journal of Gastroenterology2007，13，32： | 4 |
| 3 | Antimicrobial Agents from Selected Medicinal Plants in Libya显示文摘Objective:To test the in vitro antimicrobial efficacy of water and methanol extracts of 23 plan species that are commonly used in Libyan folk medicine.Methods:The antimicrobial activity was determinec using the well-diffusion method.Four test microorganisms were used namely,Escherichia coli,Salmonella species,Staphylococcus aureus and Bacillus subtilis.The minimum inhibitory concentration(MIC) was determined for the high biologically active crude plant extracts.Results:Among 23 medicinal plants used in the study,only 5 methanolic extracts[Rosmarinus offcinalis L,Carduus marianium L.,Lantana camara L.,Rhus tripartite(ueria) Grande,and Thymus capitatus(L.) Hoffm(link)]showed the highest antimicrobial activity againsl Staphylococcus aureus,Bacillus subtilis and Salmonella species,while 22 methanolic and aqueous extracts showed moderate to weak antimicrobial activity on all tested organisms.However 19 of the extracts showed no activity at all against Gram-ve and Gram +ve microorganisms.MIC was found to be 1.25 mg/mL(Thymus capitatus),3 mg/mL(Rhus tripartite),4 mg/mL(Carduus marianium),5 mg/mL(Rosamarinus officinalis) and5 mg/mL(Lantana camara),respectively.Conclnsions:The present results revealed that,crude methanolic extracts of the investigated Libyan folk medicinal plants exhibited mild to high in vitro antibacterial activities against Gram-positive and Gram-negative microorganisms. | Hasan MH Muhaisen Miftah Mailoud Ab-Mous Fadel A Ddeeb Aboclaid All Rtemi Omer M Taba Mehtab Parveen | 2016 | Chinese Journal of Integrative Medicine2016，22，3： | 2 |
| 4 | Prognostic Value of Promoter Hypermethylation of Retinoic Acid Receptor Beta (RARB) and CDKN2 (p16/MTS1) in Prostate Cancer显示文摘Objective: The molecular mechanism of prostate cancer is poorly understood. The aim of the study was to investigate the prevalence and prognostic value of promoter hypermethylation of retinoic acid receptor beta (RARB) and p16 among benign prostatic hyperplasia (BPH) and prostate cancer patients. Methods: In this case-control study, 63 patients were included in three groups; 21 with BPH as the control group, 21 with prostate cancer and good prognostic factors (based on prostate-specific antigen, Gleason score and stage) as good prognosis group, and 21 with prostate cancer and poor prognostic features as poor prognosis group. The prostate biopsy specimen of each individual was examined for hypermethylation of RARB and p16 promoters by methylation specific PCR (MSPCR). Results: Seven (33.3%) patients with good prognosis and 15 (71.4%) patients with poor prognosis were positive for RARB methylation, which were significantly higher than controls (P <0.0001). p16 promoter methylation was shown in 19.0% and 47.6% patients with good and poor prognosis, respectively. The RARB and p16 promoter methylation in the poor prognosis group was significantly higher than that in the good prognosis group (P =0.02 for RARB and P<0.0001 for p16). Conclusion: Hypermethylation of RARB and p16 promoters may predict prognosis in prostate cancer. | Ameri A Alidoosti A Hosseini Y Parvin M Emranpour MH Taslimi F Salehi E Fadavi P | 2011 | Chinese Journal of Cancer Research2011，23，4： | 2 |
| 5 | A G/C element mediates repression of the SM22a promoter within phenotypically modulated smooth muscle cells in experimental atherosclerosis 显示文摘 | Wamhoff BR Hoofnagle MH Burns A | 2004 | Citc Res2004，95，10： | 1 |
| 6 | Respiratory sequelae of viral diseases: from diagnosis to treatment 显示文摘 | Teper A Fischer GB Jones MH | 2002 | J Pediatr (Rio J)2002，78，2： | 1 |
| 7 | An evaluation of the quick inventory of depressive symptomatology and the hamilton rating scale for depression:a sequenced treatment alternatives to relieve depression trial report显示文摘 | Rush A J Bernstein IH Trivedi MH | 2006 | Biol Psychiatry2006，59，6： | 1 |
| 8 | Fractional photothermolysis: a review and update显示文摘 | Jih MH Kimyai-Asadi A | 2008 | Semin Cutan Med Surg2008，27，1： | 1 |
| 9 | Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers显示文摘 | SKINNER MH KUAN HY PAN A | 2003 | Clin Pharmacol Ther2003，73，3： | 1 |
| 10 | The prevalence of peripheral arterial disease in a defined population显示文摘 | Criqui MH Fronek A Barrett-Connor E | 1985 | Circulation1985，71，： | 1 |
| 11 | Internal fixation of proximal humeral fractures: current concepts显示文摘 | Hessmann MH Blum J Hofmann A | 2003 | Eur J Trauma2003，29，5： | 1 |
| 12 | In vivo sedative and gastropro- tective activities of Salvia plebeia extract and its composition of poly- phenols显示文摘 | Nugroho A Kim MH Choi J | 2012 | Archives of Pharmaeal Research2012，35，8： | 1 |
| 13 | Keeping courage during stem cell trans-plantation:a qualitative research显示文摘 | Coolbrandt A Giypdonck MH | 2010 | Eur J Oncol Nurs2010，14，3： | 1 |
| 14 | Assessment of myo- cardial perfusion and function with PET and PET/CT显示文摘 | Al-Mallah MH Sitek A Moore $C | 2010 | J Nucl Cardiol2010，17，3： | 1 |
| 15 | FOXP3 expression in hepatitis C virus-specific CD4+ T cells during acute hepatitis C显示文摘 | Heeg MH Ulsenheimer A Grü ner NH | | 0，，4： | 1 |
| 16 | Mutations of S CN1A, encoding a neuronal sodium channel, in two families with GEFS+2显示文摘 | Escayg A MacDonald BT Meisler MH | 2000 | Nat Genet2000，24，： | 1 |
| 17 | Impact of allergic rhinitis on quality of life in patients with bronchial asthma 显示文摘 | Elkholy MM Khedr MH Halawa A | 2012 | Int J Health Sci (Qassim)2012，6，2： | 1 |
| 18 | Seroprevalence of NMO- IgG Antibody in Neuromyelitis optica (NMO) and Its Specificity in Differentiating NMO from Other Demyelinating Diseases with Overlap Symptoms: An Iranian Experience显示文摘 | Harirchian MH Tafakhori A Taslimi S | 2015 | Iran J Allergy Asthma Immunol2015，14，： | 1 |
| 19 | Comparison of dexmedetomi- dine and dexamethasone for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy显示文摘 | Bakri MH Ismail EA Ihrahim A | 2015 | Korean J Anesthesiol2015，68，3： | 1 |
| 20 | A randomized controlled trial of Taichi for balance,sleep quality and cognitive performance in elderly Vietnamese 显示文摘 | Nguyen MH Kruse A | 2012 | Clin Interv in Aging2012，12，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员