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348篇 您的检索式：作者名="Mckenzie B"

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	题名	作者	年代	出处	被引量
1	NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease显示文摘AIM:To assess whether polymorphisms in NOD2 and ATG16L1 affect cytokine responses and mycobacterium avium subspecies paratuberculosis (MAP) survival in monocytes from Crohn's disease (CD) patients.METHODS:Monocytes were isolated from peripheral blood of CD patients of known genotype for common single nucleotide polymorphisms of NOD2 and ATG16L1.Monocytes were challenged with MAP and bacterial persistence assessed at subsequent time-points.Cytokine responses were assayed using a Milliplex multi-analyte profiling assay for 13 cytokines.RESULTS:Monocytes heterozygous for a NOD2 polymorphism (R702W,P268S,or 1007fs) were more permissive for growth of MAP (P=0.045) than those without.There was no effect of NOD2 genotype on subsequent cytokine expression.The T300A polymorphism ofATG16L1 did not affect growth of MAP in our model (P=0.175),but did increase expression of cytokines interleukin (IL)-10 (P=0.047) and IL-6 (P=0.019).CONCLUSION:CD-associated polymorphisms affected the elimination of MAP fromex vivo monocytes (NOD2),or expression of certain cytokines (ATG16L1),implying independent but contributory roles in the pathogenesis of CD.	Dylan M Glubb Richard B Gearry Murray L Barclay Rebecca L Roberts John Pearson Jacqui I Keenan Judy McKenzie Robert W Bentley	2011	World Journal of Gastroenterology2011，17，23：	2
2	The width of margins in radiotherapy treatment plans显示文摘	McKenzie A van Herk M Mijnheer B	2000	Phys Med Biol2000，45，11：	1
3	Cloud coverage based on all-sky imaging and its impact on surface solar irradianee 显示文摘	Pfister G McKenzie R L Liley J B	2003	Journal of Applied Meteorology2003，42，10：	1
4	Functional properties of protein i-solates from beach pea显示文摘	Chavan V D Mckenzie D B	2001	Food Chemistry2001，74，：	1
5	über oxals? ure-und weins? ure-bornylester显示文摘	ABBOT E B MCKENZIE A ROSS J D M	1938	Berichte Der Deutschen Chemischen Gesellschaft1938，71，1：	1
6	The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL- 17^+ T helper cells 显示文摘	Ivanov I I McKenzie B S Zhou L	2006	Cell2006，126，：	1
7	The SOS response regulates adaptive mutation显示文摘	McKenzie G J Harris B S Lee P L	2000	Proc Natl Acad Sci USA2000，97，：	1
8	Margins for geometric uncertainty around organs at risk in radiotherapy 显示文摘	McKenzie A van-Herk M Mijnheer B	2002	Radiother Oncol2002，62，3：	1
9	Anatomical study of the obturator forarnen and dorsal nerve of the clitoris and their relationship to minimally invasive slings 显示文摘	Achtari C Mckenzie B J Hiscock R	2006	Int Urogyneco! J Pelvic Floor Dysfunct2006，17，4：	1
10	Susceptibility of Aphis gossypii (Glover) Lo insecticides as affected by host plant using a rapid bioassay 显示文摘	McKenzie C L Cartwright B	1994	J Entomol Sci1994，29，3：	1
11	The orphan nuclear receptor RORgammat directs the differentiation program of pro - inflammatory IL - 17 + T helper ceils 显示文摘	Ivanov I I McKenzie B S Zhou L	2006	Cell2006，126，6：	1
12	Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP显示文摘	KRISHNAMURTHY B DUDEN N L MCKENZIE M D	2006	J Clin Invest2006，116，：	1
13	The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells显示文摘	Ivanov I McKenzie B Zhou L	2006	Cell2006，126，6：	1
14	Solar observations from the P78-1 satellite显示文摘	MCKENZIE D L LANDECKER P B	1982	Astrophys J1982，254，：	1
15	Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autqimmune en- cephalomyelitis显示文摘	Chen Y Langrish C L McKenzie B	2006	J Clin Invest2006，116，5：	1
16	Optimum seeding date and rate for irrigated cereal and oilseed crops in southern Alberta显示文摘	Mckenzie R H Bremer E Middleton A B	2011	Canadian Journal of Plant Science2011，91，2：	1
17	Information processing deficits asso- ciated with developmental coordination disorder: a meta - analysis of research findings 显示文摘	Wilson P H McKenzie B E	1998	J Child Psychol Psychiatry1998，39，6：	1
18	Functional Properties of Protein Isolates From Beach Pea显示文摘	Chavan V D Mckenzie D B Shahidi F	2001	Food Chem2001，74，：	1
19	Vapor Transport in Unsaturated Soil Columns: Implications for Vapor Extraction 显示文摘	Gierke J S Hutzler N J McKenzie D B	1992	Water Resources Research1992，28，2：	1
20	Understanding the IL-23-IL-17 immune pathway 显示文摘	MCKENZIE B S KASTELETIN R A CUA D J	2006	Trends Immunol2006，27，1：	1

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