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| 1 | Management of recurrent rectal cancer:A population based study in greater Amsterdam显示文摘AIM: To analyze,retrospectively in a population-based study,the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS: All rectal carcinomas diagnosed during 1998 to 2000 and initially treated with a macroscopically radical resection (632 patients) were selected from the Amsterdam Cancer Registry. For patients with recurrent disease,information on treatment of the recurrence was collected from the medical records. RESULTS: Local recurrence with or without clinically apparent distant dissemination occurred in 62 patients (10%). Thirty-two patients had an isolated local recurrence. Ten of these 32 patients (31%) underwent radical re-resection and experienced the highest survival (three quarters survived for at least 3 years). Eight patients (25%) underwent non-radical surgery (median survival 24 mo),seven patients (22%) were treated with radio-and/or chemotherapy without surgery (median survival 15 mo) and seven patients (22%) only received best supportive care (median survival 5 mo). Distant dissemination occurred in 124 patients (20%) of whom 30 patients also had a local recurrence. The majority (54%) of these patients were treated with radio-and/or chemotherapy without surgery (median survival 15 mo). Twenty-seven percent of these patients only received best supportive care (median survival 6 mo),while 16% underwent surgery for their recurrence. Survival was best in the latter group (median survival 32 mo). CONCLUSION: Although treatment options and survival are limited in case of recurrent rectal cancer after radical local resection obtained with TME,patients can benefit from additional treatment,especially if a radical resection is feasible. | Roel Bakx Otto Visser Judith Josso Sybren Meijer J Frederik M Slors J Jan B van Lanschot | 2008 | World Journal of Gastroenterology2008，14，39： | 17 |
| 2 | Preparation of thermoset rubber epoxy particles as novel toughening modifiers for glassy epoxy resins显示文摘 | JANSEN B J P TAMMINGA K Y H MEIJER E H | 1999 | Polymer1999，40，20： | 1 |
| 3 | KCI activates phospholipase D at two different concentration ranges:distinguishing between hyperosmotic stress and membrane depolarization 显示文摘 | Meijer H J Terriet B Vanhimbergen J A | 2002 | Plant J2002，31，1： | 1 |
| 4 | Characterization of the bacterial community associated with the surface and mucus layer of whiting (Merlangius merlangus)显示文摘 | SMITH C J DANILOWlCZ B S MEIJER W G | 2007 | FEMS Microbiology Ecology2007，62，1： | 1 |
| 5 | Processing of (in)tractable polymers using reactive solvents V : Morphology control during phase separation 显示文摘 | Jansen B J P Meijer H E H Lemstra P J | 1999 | Polymer1999，40，： | 1 |
| 6 | The soluble urokinase receptor is not a clinical marker for focal segmental glomerulosclerosis显示文摘 | Meijers B Maas R J Sprangers B | 2014 | Kidney Int2014，85，3： | 1 |
| 7 | High resolution microarray comparative genomic hybridisation analysis using spotted oligonucleotides显示文摘 | Carvalho B Ouwerkerk E Meijer G A | 2004 | J Clin Pathol2004，57，6： | 1 |
| 8 | The use of oryzalin as an alternative for colchicine inin-vitro chromosome doubling of Lilium and Nerine显示文摘 | Van TUYL J M MEIJER B Van DIN M P | 1992 | Acta Hort1992，325，： | 1 |
| 9 | Playing the DISC:turning on TRAIL death receptor-mediated apoptosis in cancer显示文摘 | Pennarun B Meijer A de Vries EG | 2010 | Biochim Biophys Acta2010，1805，2： | 1 |
| 10 | Police Message Diffu- sion on Twitter: Analysing the Reach of Social Media Communi- cations显示文摘 | Van De Velde B Meijer A Homburg V | 2015 | Behaviour & Information Technology2015，34，1： | 1 |
| 11 | Farnesol-induced apoptosis in Candida albicans显示文摘 | Shirtliff M E Krom B P Meijering R A Peters B M Zhu J Scheper M A | 2009 | Antimicrob Agents Chemother2009，53，： | 1 |
| 12 | Residual renal function is an independent determinant of serum FGF-23 levels in dialysis patients显示文摘 | Viaene L Bammens B Meijers BK | 2012 | Nephrol Dial Transplant2012，27，： | 1 |
| 13 | The pectin content as a measure of the retting and rettability of flax显示文摘 | MEIJER W J M VERTREGT N RUTGERS B | 1995 | Industrial Crops and Products1995，，4： | 1 |
| 14 | Removal of the uremicretention solute p-cresol using fractionated plasma separation andadsorption显示文摘 | Meijers BK Weber V Bammens B | 2008 | Artif Organs2008，32，3： | 1 |
| 15 | Downconversion for solar ceils in YF3:Nd3 +,Yb3 +显示文摘 | Meijer J M Aarts L van der Ende B M | | 0，，： | 1 |
| 16 | An experimental system for auditory image representations显示文摘 | MEIJER P B L | 1992 | IEEE Transaction on Biomedical Engineering1992，39，2： | 1 |
| 17 | Thrombin-activatable fibrinolysis inhibitor (TAFI,plasma procarboxypepti- dase B, procarboxypeptidase R, procarboxypeptidase U) 显示文摘 | BOUMA B N MEIJERS J C | 2003 | J Thromb Haemost2003，1，： | 1 |
| 18 | Topologically consistent 3D city models obtained by extrusion显示文摘 | Ledoux H Meijers B M | 2011 | lntemational Journal of Geographical Information Science2011，25，4： | 1 |
| 19 | Playing the DISC:turning on TRAIL death receptor-mediated apoptosis in cancer显示文摘 | Pennarun B Meijer A de Vries EGE | 2010 | BBA-Rev Cancer2010，1805，2： | 1 |
| 20 | Regulation of fibrinolysis in plasma by TAFI and protein C is dependent on the concentration of thrombomodulin显示文摘 | Mosnier L O Meijers J C Bouma B N | 2001 | Thromb Haemost2001，85，1： | 1 |
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