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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Lack of microRNA‐101 causes E‐cadherin functional deregulation through EZH2 up‐regulation in intestinal gastric cancer显示文摘 | Joana Carvalho Nicole C van Grieken Patricia M Pereira Sónia Sousa Marianne Tijssen Tineke E Buffart Bego?a Diosdado Heike Grabsch Manuel AS Santos Gerrit Meijer Raquel Seruca Beatriz Carvalho Carla Oliveira | 2012 | J Pathol2012，，1： | 3 |
| 3 | Solution-processed ambipolar organic field-effect transistors and inverters显示文摘 | Meijer E J De Leeuw D M Setayesh S | | 0，，10： | 1 |
| 4 | Metabolic modelling of full-scale biological nitrogen and phosphorus removing WWTP's 显示文摘 | Meijer S Van Loosdrecht M Heijnen J J | 2001 | Water Research2001，35，11： | 1 |
| 5 | Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012-2013显示文摘 | Meijer A Rebelo-de-Andrade H Correia V Besselaar T Drager-Dayal R Fry A Gregory V Gubareva L Kageyama T Laekenby A Lo J Odagiri T Pere- yaslov D Siqueira M M Takashita E Tashiro M Wang D Wong S Zhang W Daniels R S Hurt A C | 2014 | An- tiviral Research2014，110，： | 1 |
| 6 | Characterization of the bacterial community associated with the surface and mucus layer of whiting (Merlangius merlangus)显示文摘 | SMITH C J DANILOWlCZ B S MEIJER W G | 2007 | FEMS Microbiology Ecology2007，62，1： | 1 |
| 7 | Intradermal blue dye to identify sentinel lymph node in breast cancer显示文摘 | Borgstein PJ Meijer S Pijpers R | 1997 | Lancet1997，349，： | 1 |
| 8 | The global re-cycling of persistent organic pollutants is strongly retarded by soils 显示文摘 | Ockenden W A Breivik K Meijer S N | 2003 | Environmental Pollution2003，121，1： | 1 |
| 9 | Intradermal blue dye to identify the sentinel lymph node in breast cancer显示文摘 | BORGSTEIN PJ MEIJER S PIJPERS R | 1997 | Lancet1997，349，： | 1 |
| 10 | Model-based evaluation of two BNR processes - UCT and A2N显示文摘 | Hao X D van Loosdrecht M C M Meijer S C F | 2001 | Water Res2001，35，12： | 1 |
| 11 | The Global Recycling of Persistent Organic Pollutants is Strongly Retarded by SOils显示文摘 | Ockenden W A Breivik K Meijer S N | 2003 | Environmental Pollution2003，121，1： | 1 |
| 12 | Corporate social performance as a bot- tom line for consumers显示文摘 | Meijer M Theo S | 2005 | Business and Society2005，44，4： | 1 |
| 13 | 显示文摘 | Aida T Meijer E W Stupp S I | 2012 | Science2012，335，6070： | 1 |
| 14 | Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish 显示文摘 | Meijer A H Gabby Krens S Medina Rodriguez I A | 2004 | Molecular Immunology2004，40，11： | 1 |
| 15 | An experimental aquarium for observing the schooling behavior of Antarctic krill(Euphausia superba)显示文摘 | Kawaguchi S King R Meijers R | 2010 | Deep-Sea Research II2010，57，： | 1 |
| 16 | Inhibition of Cyclin-dependent Kinases by Purine Ana?logues Crystal Structure of Human Cdk2 Complexed with Roscovitine显示文摘 | DE AZEVEDO W F LECLERC S MEIJER L | 1997 | EurJ Biochern1997，243，： | 1 |
| 17 | Reference value of transcutaneous oxygen measurement in diabetic patients compared with nondiabetic patients显示文摘 | Meijer VE Vant Sant HP Spronk S | 2008 | J Vasc Surg2008，48，2： | 1 |
| 18 | Functional lymphatic anatomy for sentinel node biopsy in breast cancer: echoes from the past and the periareolar blue method显示文摘 | BORGSTEIN P J MEIJER S PIJPERS R J | 2000 | Ann Surg2000，232，1： | 1 |
| 19 | Metabolic modeling of full-scale biological nitrogen and phosphorus removing wwtp 显示文摘 | Meijer S C F van Loosdrecht M C M Heijnen J J | 2001 | WaterRes2001，，35： | 1 |
| 20 | Global distribution and budget of PCBs and HCB in background surface soils:Implications for sources and environmental processes显示文摘 | Meijer S N Ockenden W A Sweetman A Breivik K Grimalt J O Jones K C | 2003 | Environmental Science and Technology2003，37，： | 1 |
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