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| 1 | A chlorinated low-bandgap small-molecule acceptor for organic solar cells with 14.1% efficiency and low energy loss显示文摘A new acceptor-donor-acceptor(A-D-A) type small-molecule acceptor NCBDT-4 Cl using chlorinated end groups is reported.This new-designed molecule demonstrates wide and efficient absorption ability in the range of 600–900 nm with a narrow optical bandgap of 1.40 eV. The device based on PBDB-T-SF:NCBDT-4 Cl shows a power conversion efficiency(PCE) of 13.1%without any post-treatment, which represents the best result for all as-cast organic solar cells(OSCs) to date. After device optimizations, the PCE was further enhanced to over 14% with a high short-circuit current density(Jsc) of 22.35 m A cm-2 and a fill-factor(FF) of 74.3%. The improved performance was attributed to the more efficient photo-electron conversion process in the optimal device. To our knowledge, this outstanding efficiency of 14.1% with an energy loss as low as 0.55 eV is among the best results for all single-junction OSCs. | Bin Kan Huanran Feng Huifeng Yao Meijia Chang Xiangjian Wan Chenxi Li Jianhui Hou Yongsheng Chen | 2018 | Science China Chemistry2018，61，10： | 9 |
| 2 | Metal-Organic Frameworks-Based Fluorescent Nanocomposites for Bioimaging in Living Cells and in vivo显示文摘Metal-organic frameworks(MOFs)as a class of porous functional materials have attracted more and more attention for biomedical applications.To date,MOFs have been developed for bioimaging based on a series of advantages such as the large surface areas,high porosity,fluorescence functionalities and good biocompatibility.It is worth noting that organic or inorganic fluorescent materials such as fluorescent dyes,quantum dots,metal nanoclusters and nanosheets can combine MOFs or be encapsulated in MOFs to form fluorescent nanocomposites for excellent imaging function.Importantly,excellent imaging capabilities are of great significance in living cells and in vivo for detection,diagnosis and cancer therapy.In this review,we focus on the recent research of the bioimaging in living cells and in vivo based on various MOF-based nanocomposites and their potential biological clinical applications. | Meijia Liu Xiangling Ren Xianwei Meng Hongbo Li | 2021 | Chinese Journal of Chemistry2021，39，2： | 8 |
| 3 | Superior de/hydrogenation performances of MgH2 catalyzed by 3D flower-like TiO2@C nanostructures显示文摘Magnesium hydride has been seen as a potential material for solid state hydrogen storage,but the kinetics and thermodynamics obstacles have hindered its development and application.Three-dimensional flower-like TiO2@C and TiO2 were synthesized as the catalyst for MgH2 system and great catalytic activities are acquired in the hydrogen sorption properties.Experiments also show that the flower-like TiO2@C is superior to flower-like TiO2 in improving the hydrogen storage properties of MgH2.The hydrogen desorption onset and peak temperatures of flower-like TiO2 doped MgH2 is reduced to 199.2℃and 245.4℃,while the primitive MgH2 starts to release hydrogen at 294.6℃and the rapid dehydrogenation temperature is even as high as 362.6℃.The onset and peak temperatures of flower-like TiO2@C doped MgH2 are further reduced to 180.3℃and 233.0℃.The flower-like TiO2@C doped MgH2 composite can release6.0 wt%hydrogen at 250℃within 7 min,and 4.86 wt%hydrogen at 225℃within 60 min,while flowerlike TiO2 doped MgH2 can release 6.0 wt%hydrogen at 250℃within 8 min,and 3.89 wt%hydrogen at225℃within 60 min.Hydrogen absorption kinetics is also improved dramatically.Moreover,compared with primitive MgH2 and the flower-like TiO2 doped MgH2,the activation energy of flower-like TiO2@C doped MgH2 is significantly decreased to 67.10 kJ/mol.All the improvement of hydrogen sorption properties can be ascribed to the flower-like structure and the two-phase coexistence of TiO2 and amorphous carbon.Such phase composition and unique structure are proved to be the critical factor to improve the hydrogen sorption properties of MgH2,which can be considered as the new prospect for improving the kinetics of light-metal hydrogen storage materials. | Meng Zhang Xuezhang Xiao Bosang Luo Meijia Liu Man Chen Lixin Chen | 2020 | Journal of Energy Chemistry2020，29，7： | 5 |
| 4 | Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression显示文摘Cholangiocarcinoma(CCA)has emerged as an intractable cancer with scanty therapeutic regimens.The aberrant activation of Yes-associated protein(YAP)and transcriptional co-activator with PDZ-binding motif(TAZ)are reported to be common in CCA patients.However,the underpinning mechanism remains poorly understood.Deubiquitinase(DUB)is regarded as a main orchestrator in maintaining protein homeostasis.Here,we identified Josephin domain-containing protein 2(JOSD2)as an essential DUB of YAP/TAZ that sustained the protein level through cleavage of polyubiquitin chains in a deubiquitinase activity-dependent manner.The depletion of JOSD2 promoted YAP/TAZ proteasomal degradation and significantly impeded CCA proliferation in vitro and in vivo.Further analysis has highlighted the positive correlation between JOSD2 and YAP abundance in CCA patient samples.Collectively,this study uncovers the regulatory effects of JOSD2 on YAP/TAZ protein stabilities and profiles its contribution in CCA malignant progression,which may provide a potential intervention target for YAP/TAZ-related CCA patients. | Meijia Qian Fangjie Yan Weihua Wang Jiamin Du Tao Yuan Ruilin Wu Chenxi Zhao Jiao Wang Jiabin Lu Bo Zhang Nengming Lin Xin Dong Xiaoyang Dai Xiaowu Dong Bo Yang Hong Zhu Qiaojun He | 2021 | Acta Pharmaceutica Sinica B2021，11，12： | 5 |
| 5 | Fluvial facies reservoir productivity prediction method based on principal component analysis and artificial neural network显示文摘It is difficult to forecast the well productivity because of the complexity of vertical and horizontal developments in fluvial facies reservoir.This paper proposes a method based on Principal Component Analysis and Artificial Neural Network to predict well productivity of fluvial facies reservoir.The method summarizes the statistical reservoir factors and engineering factors that affect the well productivity,extracts information by applying the principal component analysis method and approximates arbitrary functions of the neural network to realize an accurate and efficient prediction on the fluvial facies reservoir well productivity.This method provides an effective way for forecasting the productivity of fluvial facies reservoir which is affected by multifactors and complex mechanism.The study result shows that this method is a practical,effective,accurate and indirect productivity forecast method and is suitable for field application. | Pengyu Gao Chong Jiang Qin Huang Hui Cai Zhifeng Luo Meijia Liu | 2016 | Petroleum2016，2，1： | 4 |
| 6 | Mesoporous Ag nanocubes synthesized via selectively oxidative etching at room temperature for surface- enhanced Raman spectroscopy显示文摘Silver nanocubes enriched with {100} facets have been extensively used for surface-enhanced Raman scattering. Herein, we report a new water-phase synthesis method for weU-defined Ag nanocubes with tunable sizes via a two-step procedure at room temperature. First, irregularly shaped Ag nanoparticles (INPs) were prepared by reducing silver ammonia solution using ethylal. Second, the agglomerated INPs were selectively etched with HNO3 and C1- to yield {100} facet-rich mesoporous Ag nanocubes. The mechanism of Ag-nanocube formation and growth was investigated in detail by elucidating the involved chemical reactions and physical changes at each step during the synthesis. The addition of C1- anions was responsible for facilitating Ag nanoparticle growth by removing surface-adsorbed Ag+ species, thereby eliminating inter-particle repulsive forces. This agglomeration was found crucial for the subsequent selective oxidation of Ag nanoparticles because the protective agent used, polyvinylpyrrolidone (PVP), was the most effective one for adsorption on the surfaces of Ag nanoparticles of size greater than approximately 50 nm. Importantly mesopores were found inside the Ag nanocubes; this can be attributed to the unavoidable imperfect packing during the agglomeration of INPs. The newly prepared Ag nanocubes were further used to enhance the Raman signal of rhodamine 6G, which is capable of reducing the detection limitation to 10-16 mol·L-1. | Lin Gan Meijia Yang Xi Ke Guofeng Cui Xudong Chen Shiva Gupta William Kellogg Drew Higgins Gang Wu | 2015 | Nano Research2015，8，7： | 4 |
| 7 | Self-healing routing: failure,modeling and analysis显示文摘Network failures occur frequently, and self-healing ability of existing routing protocols cannot guarantee fast route convergence under these failures without impacting packet forwarding. During routing convergence, network routes may be incorrect and even routing black holes and loops occur, which will result in extensive packet loss and thus influence network performance. To solve this problem, several improved routing solutions have been proposed. In this paper, we propose the concept and model of self-healing routing and analyze the key problems in current intra-domain and inter-domain self-healing routing protocols after briefly reviewing the characteristics of network failures. We classify the different self-healing solutions into two categories based on their design principles: routing restoration and routing protection, and systematically analyze these different typical solutions. Finally, we discuss several key issues in self-healing routing and propose a hybrid protection and restoration based routing scheme. | XU MingWei 1,2 , LI Qi 1,2 , YANG Yuan 1,2 , HOU MeiJia 1,2 & PAN LingTao 1,2 1 Department of Computer Science, Tsinghua University, Beijing 100084, China 2 Tsinghua National Laboratory for Information Science and Technology (TNList), Beijing 100084, China | 2011 | Science China(Information Sciences)2011，54，3： | 3 |
| 8 | Enzymatic hydrolysis of silkworm pupa and its allergenicity evaluation by animal model with different immunization routes显示文摘Silkworm pupa is a nourishing food with high nutritional value,but its consumption has been greatly limited given its allergenicity.Enzyme hydrolytic technique is recognized as an effective method to reduce the allergenicity of protein.In this study,we aimed to investigate the effect of enzymolysis on the allergenicity of silkworm pupa.Crude silkworm pupa protein was extracted through alkali extraction and acid precipitation,which included 5 proteins with the molecular weights ranging from 34 kDa to 76 kDa,and silkworm pupa were then hydrolyzed by alkaline protease.The allergenicity of silkworm pupa protein and its enzymatic hydrolysates was evaluated by establishing BALB/c mice model,and the mice were immunized via intragastric gavage and intraperitoneal injection,respectively.The results indicated that the intraperitoneal inj ection immunization route induced more by detecting with antibodies,histamine and Th2-related cytokines.Moreover,mice treated with silkworm pupa protein peptide displayed no obvious allergic symptoms,indicating that enzyme hydrolytic technique could significantly reduce the allergenicity of silkworm pupa. | Yan Dai Meijia Huang Yujuan Xu Lixia Mu Jingyan Gao Hongbing Chen Zhihua Wu Anshu Yang Yong Wu Xin Li | 2023 | Food Science and Human Wellness2023，12，3： | 3 |
| 9 | A Personalized Search Model Using Online Social Network Data Based on a Holonic Multiagent System显示文摘Personalized search utilizes user preferences to optimize search results,and most existing studies obtain user preferences by analyzing user behaviors in search engines that provide click-through data.However,the behavioral data are noisy because users often clicked some irrelevant documents to find their required information,and the new user cold start issue represents a serious problem,greatly reducing the performance of personalized search.This paper attempts to utilize online social network data to obtain user preferences that can be used to personalize search results,mine the knowledge of user interests,user influence and user relationships from online social networks,and use this knowledge to optimize the results returned by search engines.The proposed model is based on a holonic multiagent system that improves the adaptability and scalability of the model.The experimental results show that utilizing online social network data to implement personalized search is feasible and that online social network data are significant for personalized search. | Meijia Wang Qingshan Li Yishuai Lin | 2020 | China Communications2020，17，2： | 2 |
| 10 | A critical review of extracellular polymeric substances (EPSS) in membrane bioreactors: Characteristics, roles in membrane fouling and control strategies 显示文摘 | LIN Hongjun ZHANG Meijia WANG Fangyuan | 2014 | Journal of Membrane Science2014，460，11： | 1 |
| 11 | Preparation and properties of nanostructure anatase TiOz monoliths using 1-butyl-3-methylimidazolium tetrafluoroborate room-temperature ionic Liquids as Template Solvents显示文摘 | Yang Liu Jun Li Meijia Wang | 2005 | Crystal Growth Design2005，5，4： | 1 |
| 12 | Is CEO pay in high- technology firms related to innovation? 显示文摘 | Balkin D B G D Markman Gomez- Meijia | 2000 | Academy of Man- agement Journal2000，，6： | 1 |
| 13 | Sensitive im- munosensor for the label-free determination of tumor marker based on carbon nanotubes/mesoporous silica and graphene modified electrode 显示文摘 | Wei Zhijing Zhang Huihui Sha Meijia | 2013 | Biosensors and Bioelec- tronics2013，41，： | 1 |
| 14 | Multiplicity of solutions for integral boundary value problems of fractional differential equations with upper and lower solutions显示文摘 | MeiJia Xiping Liu | 2014 | Applied Mathematics and Computation2014，232，1： | 1 |
| 15 | A Three-dimensional Non-fullerene Small Molecule Acceptor for Solution-processed Organic Solar Cellst显示文摘 | Meijia Chang Yunchuang Wang Nailiang Qiu Yuan-Qiu-Qiang Yi Xiangjian Wan Chenxi Li Yongshen Chen | 2017 | Chinese Journal of Chemistry2017，35，11： | 1 |
| 16 | The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption molecular human reproduction 显示文摘 | Zhang Meijia Hong Ouyang Xia Guoliang | 2009 | Mol Hum Reprod2009，15，7： | 1 |
| 17 | Thermal and Thermal Stress Analysis of a Thin Film Thermo Electric Cooler Under the Influence of the Thomson Effect显示文摘 | Huang Meijia Chou Pokuai Lin Mingchuan | 2006 | Sensors and Actuators A2006，126，： | 1 |
| 18 | A novel approach for quantitative evaluation of the physicochemical interactions between rough membrane surface and sludge foulants in a submerged membrane bioreactor 显示文摘 | Hongjnn Lin Meijia Zhang Rongwu Mei | 2014 | Bioresource Technology2014，171，： | 1 |
| 19 | Is CEO pay in high- technology finns related to innovation? 显示文摘 | Balkin D B G D Markman Gomez - Meijia | 2000 | Academy of Management Journal2000，43，6： | 1 |
| 20 | Fungal endophytes limit pathogen damage in a tropical tree 显示文摘 | Arnold A E Meijia L C Kyllo D et a! | 2003 | Proc Natl Acad Sci USA2003，100，15： | 1 |
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