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| 1 | Hepatitis B virus subgenotype F3 reactivation with vaccine escape mutations:A case report and review of the literature显示文摘Hepatitis B represents a global health threat because its chronic course and sequelae contribute to a high morbidity and mortality. Hepatitis B virus(HBV) infection can be controlled by vaccines, antiviral treatment, and by interrupting transmission. Rare vaccine escape mutants are serious because they eliminate vaccine protection. Here, we present a 74-year-old vaccinated patient with HBV reactivation 11 years after kidney transplantation. The patient was HBV-positive but HBs Ag-negative prior to vaccination 6 years before transplantation. The reactivated virus was HBV genotype F3 with vaccine escape mutations G145 R, P120 Q, and Q129 P. The patient was successfully treated with entecavir. The epidemiological reasons for this subgenotype, which is extremely rare in Western Europe, were unclear. This case illustrates that second-generation vaccines are not always effective in a specific group of patients. | Stefan Schlabe Kathrin van Bremen Souhaib Aldabbagh Dieter Glebe Corinna M Bremer Tobias Marsen Walter Mellin Veronica Di Cristanziano Anna M Eis-Hübinger Ulrich Spengler | 2018 | World Journal of Hepatology2018，10，7： | 2 |
| 2 | Patients compliance显示文摘 | Mellins RB Evan D Zimmermam B | 1992 | Am Rev Respir Dis1992，146，4： | 1 |
| 3 | Developing and shedding inhibitions:how MHC class Ⅱ molecules reach maturity显示文摘 | Busch R Mellins ED | 1996 | Curr Opin Immunol1996，8，： | 1 |
| 4 | Behavioral risk in early adolescents with HIV + mothers 显示文摘 | Mellins CA Brackis-Cott E Dolezal C | 2005 | J Adolesc Health2005，36，4： | 1 |
| 5 | Quality changes diuing iced and frozen storage of tuna flesh treated with carbon monoxide gas显示文摘 | CHOW Chaujen HSIEH Pingping TSAI Mellin | 1998 | Journal of Food and Drug Analysis1998，6，3： | 1 |
| 6 | Triple ACE-ECE NEP inhibition in heart failure:a compareson with ACE and dual ECE-NEP inhibition显示文摘 | MELLIN V JENG A Y MONTEIL C | 2005 | J Cardiovasc Pharmacol2005，46，： | 1 |
| 7 | Disclosure of an HIV diagnosis to children:history,current research,and future directions显示文摘 | Wiener L Mellins CA Marhefka S | 2007 | J Dev BehavPediatr2007，28，2： | 1 |
| 8 | The IL-23/IL-17 axis in psoriatic arthritis显示文摘 | Suzuki E Mellins ED Gershwin ME | 2014 | Autoimmunity Reviews2014，13，45： | 1 |
| 9 | Breaking old paradigms : Th17 cells in autoim- mune arthritis 显示文摘 | Peck A Mellins ED | 2009 | Clin Immuno12009，132，3： | 1 |
| 10 | Multicenter Study of Pectus Excavatum, Final Report Complications, Static/Exercise Pulmonary Function, and Anatomic Outcomes 显示文摘 | Kelly RE Jr Mellins RI3 Shamberger RC | 2013 | J Am Coll Surgeons2013，217，6： | 1 |
| 11 | Cytophotometry in tumor pathology:a critical review of methods and applications,and some results of DNA analysis显示文摘 | Mellin W | 1990 | Pathol Res Pract1990，186，1： | 1 |
| 12 | Flow cytometric DNA analysis of bone tumor显示文摘 | MELLIN W GRUNDMANN E ROESSNER A | 1989 | Curr Top in Pathol1989，80，： | 1 |
| 13 | Acidic fibroblast growth factor accelerates dermal wound healing in diabetic mice显示文摘 | Mellin TN Cashen DE Ronan JJ | 1995 | J Invest Dermatol1995，104，5： | 1 |
| 14 | neuropharma- cology of the parasitic trematode,schistosoma-mansoni显示文摘 | MELLIN T N BUSCH R D WANG C C | 1983 | Ameri- can Journal of Tropical Medicine and Hygiene1983，，32： | 1 |
| 15 | Transient reduction in myocardial free oxygen radical levels is involved in the improved cardiac function and structure after long-term allopurinol treatment initiated in established chronic heart failure显示文摘 | Mellin V Isabelle M Oudot A Vergely-Vandriesse C Monteil C Di Meglio B | 2005 | Eur Heart J2005，26，： | 1 |
| 16 | Plasticity of T-cell phenotype and function: the T helper type 17 example 显示文摘 | Peck A Mellins ED | 2009 | Immunology2009，129，2： | 1 |
| 17 | Breaking old paradigms: Thl7 cells in autoimmune arthritis显示文摘 | Peck A Mellins ED | 2009 | Clin Immunol2009，132，3： | 1 |
| 18 | Lung injury from smoke inhalation 显示文摘 | Lee A S Mellins R B | 2006 | Paediatr Respir Rev2006，7，2： | 1 |
| 19 | Long-term psycho-social challenges for people living with HIV: Let's not forget the individual in our global response to t he pandemic显示文摘 | Remien R H Mellins C A | 2007 | AIDS2007，，5： | 1 |
| 20 | Plasticity of T-cell phenotype and function:the T helper type 17 example显示文摘 | PECK A MELLINS ED | 2010 | Immunol- ogy2010，129，2： | 1 |
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