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| 1 | Treatment technologies for aqueous perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA)显示文摘Fluorochemicals(FCs)are oxidatively recalcitrant,environmentally persistent,and resistant to most conventional treatment technologies.FCs have unique physiochemical properties derived from fluorine which is the most electronegative element.Perfluorooctanesulfonate(PFOS),and perfluorooctanoate(PFOA)have been detected globally in the hydrosphere,atmosphere and biosphere.Reducing treatment technologies such as reverses osmosis,nano-filtration and activated carbon can remove FCs from water.However,incineration of the concentrated waste is required for complete FC destruction.Recently,a number of alternative technologies for FC decomposition have been reported.The FC degradation technologies span a wide range of chemical processes including direct photolysis,photocatalytic oxidation,photochemical oxidation,photochemical reduction,thermally-induced reduction,and sonochemical pyrolysis.This paper reviews these FC degradation technologies in terms of kinetics,mechanism,energetic cost,and applicability.The optimal PFOS/PFOA treatment method is strongly dependent upon the FC concentration,background organic and metal concentration,and available degradation time. | Chad D.VECITIS Hyunwoong PARK Jie CHENG Brian T.MADER Michael R.HOFFMANN | 2009 | Frontiers of Environmental Science & Engineering2009，3，2： | 26 |
| 2 | Computed tomography and magnetic resonance imaging evaluation of lymph node metastasis in early colorectal cancer显示文摘AIM: To assess the role of computed tomography(CT) and magnetic resonance imaging(MRI) and establish imaging criteria of lymph node metastasis in early colorectal cancer.METHODS: One hundred and sixty patients with early colorectal cancer were evaluated for tumor location, clinical history of polypectomy, depth of tumor invasion, and lymph node metastasis. Two radiologists assessed preoperative CT and/or MRI for the primary tumor site detectability, the presence or absence of regional lymph node, and the size of the largest lymph node. Demographic, imaging, and pathologic findings were compared between the two groups of patients based on pathologic lymph node metastasis and optimal size criterion was obtained.RESULTS: The locations of tumor were ascending, transverse, descending, sigmoid colon, and rectum. One hundred and sixty early colorectal cancers were classified into 3 groups based on the pathological depth of tumor invasion; mucosa, submucosa, and depth unavailable. A total of 20(12.5%) cancers with submucosal invasion showed lymph node metastasis. Lymph nodes were detected on CT or MRI in 53 patients. The detection rate and size of lymph nodes were significantly higher(P = 0.000, P = 0.044, respectively) in patients with pathologic nodal metastasis than in patients without nodal metastasis. Receiver operating curve analysis showed that a cut-off value of 4.1 mm is optimal with a sensitivity of 78.6% and specificity of 75%.CONCLUSION: The short diameter size criterion of≥ 4.1 mm for metastatic lymph nodes was optimal for nodal staging in early colorectal cancer. | Joonsung Choi Soon Nam Oh Dong-Myung Yeo Won Kyung Kang Chan-Kwon Jung Sang Woo Kim Michael Yong Park | 2015 | World Journal of Gastroenterology2015，21，2： | 16 |
| 3 | Arabidopsis CAMTA Transcription Factors Regulate Pipecolic Acid Biosynthesis and Priming of Immunity Genes显示文摘The Arabidopsis thaliana Calmodulin-binding Transcription Activator(CAMTA)transcription factors CAMTA1,CAMTA2,and CAMTA3(CAMTA123)serve as master regulators of salicylic acid(SA)-mediated immunity,repressing the biosynthesis of SA in healthy plants.Here,we show that CAMTA123 also repress the biosynthesis of pipecolic acid(Pip)in healthy plants.Loss of CAMTA123 function resulted in the induction of AGD2-like defense response protein 1(ALD1),which encodes an enzyme involved in Pip biosynthesis.Induction of ALD1 resulted in the accumulation of high levels of Pip,which brought about increased levels of the SA receptor protein NPR1 without induction of NPR1 expression or requirement for an increase in SA levels.Pip-mediated induction of ALD1 and genes regulating the biosynthesis of SA—CBP60g,SARD1,PAD4,and EDS1—was largely dependent on NPR1.Furthermore,Pip-mediated increase in NPR1 protein levels was associated with priming of Pip and SA biosynthesis genes to induction by low levels of SA.Taken together,our findings expand the role for CAMTA123 in regulating key immunity genes and suggest a working model whereby loss of CAMTA123 repression leads to the induction of plant defense genes and initiation of SAR. | Yongsig Kim Sarah J.Gilmour Lumen Chao Sunchung Park Michael F.Thomashow | 2020 | Molecular Plant2020，13，1： | 8 |
| 4 | IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer显示文摘 | Florian R. Greten Lars Eckmann Tim F. Greten Jin Mo Park Zhi-Wei Li Laurence J. Egan Martin F. Kagnoff Michael Karin | 2004 | Cell2004，，3： | 4 |
| 5 | 基于简易微波方法制备高性能MoS2/石墨烯纳米复合材料用于高效析氢反应(英文)显示文摘用于析氢反应(HER)的低成本、高效能催化剂对于推进基于清洁氢气的能源工业非常重要.二维二硫化钼(MoS2)具有显著的催化性能,因而已被人们广泛深入研究.然而,大多数现有的合成方法耗时、复杂且效率较低.本文通过超快(60秒)微波引发的方法生产MoS2/石墨烯催化剂.石墨烯的高比表面积和导电性为MoS2纳米片的生长提供了有利的导电网络和快速电荷转移动力.文中制备的MoS2/石墨烯纳米复合材料在酸性介质中对HER表现出优异的电催化活性,具有62 mV的低起始电位,高阴极电流和43.3mV/dec的Tafel斜率.除了优异的催化活性外, MoS2/石墨烯还具有较长的循环稳定性,在250 mV的过电位下阴极电流密度高达1000 mA cm^-2.此外, MoS2/石墨烯催化剂在30–120°C范围内具有出色的HER活性和36.51 kJ mol^-1的低活化能,提供了潜在的大批量生产和制备的机会. | Shatila Sarwar Amit Nautiyal Jonathan Cook 袁一斐 李俊豪 Sunil Uprety Reza Shahbazian-Yassar 王瑞刚 Minseo Park Michael J.Bozack 张新宇 | 2020 | Science China Materials2020，63，1： | 4 |
| 6 | Pancreatic hardness: Correlation of surgeon's palpation, durometer measurement and preoperative magnetic resonance imaging features显示文摘AIM To evaluate the correlation between subjective assessments of pancreatic hardness based on the palpation, objective measurements using a durometer, and magnetic resonance imaging(MRI) findings for assessing pancreatic hardness.METHODS Eighty-three patients undergoing pancreatectomies were enrolled. An experienced surgeon subjectively evaluated the pancreatic hardness in the surgical field by palpation. The pancreatic hardness was also objectivelyevaluated using a durometer. Preoperative MRI findings were evaluated by a radiologist in terms of the apparent diffusion coefficient(ADC) values, the relative signal intensity decrease(RSID) of the pancreatic parenchyma, and the diameter of the pancreatic parenchyma and duct. Durometer measurement results, ADC values, RSID, pancreatic duct and parenchyma diameters, and the ratio of the diameters of the duct and parenchyma were compared between pancreases judged to be soft or hard pancreas on the palpation. A correlation analysis was also performed between the durometer and MRI measurements.RESULTS The palpation assessment classified 44 patients as having a soft pancreas and 39 patients as having a hard pancreas. ADC values were significantly lower in the hard pancreas group. The ductal diameter and duct-to-pancreas ratio were significantly higher in the hard pancreas group. For durometer measurements, a correlation analysis showed a positive correlation with the ductal diameter and the duct-to-pancreas ratio and a negative correlation with ADC values. CONCLUSION Hard pancreases showed lower ADC values, a wider pancreatic duct diameter and a higher duct-to-pancreas ratio than soft pancreases. Additionally, the ADC values, diameter of the pancreatic duct and duct-to-pancreas ratio were closely correlated with the durometer results. | Tae Ho Hong Joon-Il Choi Michael Yong Park Sung Eun Rha Young Joon Lee Young Kyoung You Moon Hyung Choi | 2017 | World Journal of Gastroenterology2017，23，11： | 3 |
| 7 | ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension显示文摘 | Vallerie V. McLaughlin Stephen L. Archer David B. Badesch Robyn J. Barst Harrison W. Farber Jonathan R. Lindner Michael A. Mathier Michael D. McGoon Myung H. Park Robert S. Rosenson Lewis J. Rubin Victor F. Tapson John Varga | 2009 | Journal of the American College of Cardiology2009，，17： | 2 |
| 8 | 新技术新装置提高炼能——石脑油催化裂解(ACO)生产低碳烯烃显示文摘源自蒸汽裂解和炼油厂的丙烯将无法满足未来对丙烯的需求,所以新技术的盛行也并非偶然。ACO工艺采用直馏石蜡基馏份作为原料,可以生产比传统热裂解工艺更多的烯烃,丙烯/乙烯比(P/E)之比高达1:1。如今,SK能源公司已建造了世界上第一个ACO装置,并在2010年最后一个季度投入生产。接下来,商业催化剂的性能会进一步被验证。 | Michael J Tallman Curtis Eng Sun Choi Deuk Soo Park | 2011 | 科技信息(石油与装备)2011，，1： | 2 |
| 9 | Sulfonated hydrocarbon membranes for medium-temperature and low-humidity proton exchange membrane fuel cells (PEMFCs)显示文摘 | Chi Hoon Park Chang Hyun Lee Michael D. Guiver Young Moo Lee | 2011 | Progress in Polymer Science2011，，11： | 2 |
| 10 | Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial显示文摘 | Edward B Garon Tudor-Eliade Ciuleanu Oscar Arrieta Kumar Prabhash Konstantinos N Syrigos Tuncay Goksel Keunchil Park Vera Gorbunova Ruben Dario Kowalyszyn Joanna Pikiel Grzegorz Czyzewicz Sergey V Orlov Conrad R Lewanski Michael Thomas Paolo Bidoli Shaker | 2014 | The Lancet2014，，： | 2 |
| 11 | Continuous Low-Level Vagus Nerve Stimulation Reduces Stellate Ganglion Nerve Activity and Paroxysmal Atrial Tachyarrhythmias in Ambulatory Canines显示文摘 | Mark J. Shen Tetsuji Shinohara Hyung-Wook Park Kyle Frick Daniel S. Ice Eue-Keun Choi Seongwook Han Mitsunori Maruyama Rahul Sharma Changyu Shen Michael C. Fishbein Lan S. Chen John C. Lopshire Douglas P. Zipes Shien-Fong Lin Peng-Sheng Chen | 2011 | Circulation2011，，20： | 2 |
| 12 | Emerging roles of circular RNAs in retinal diseases显示文摘Retinal disorders are a group of ocular diseases whose onset is associated with a number of aberrant molecular and cellular processes or physical damages that affect retinal structure and function resulting in neural and vascular degeneration in the retina.Current research has primarily focused on delaying retinal disease with minimal success in preventing or reversing neuronal degeneration.In this review,we explore a relatively new field of research involving circular RNAs,whose potential roles as biomarkers and mediators of retinal disease pathogenesis have only just emerged.While knowledge of circular RNAs function is limited given its novelty,current evidence has highlighted their roles as modulators of microRNAs,regulators of gene transcription,and biomarkers of disease development and progression.Here,we summarize how circular RNAs may be implicated in the pathogenesis of common retinal diseases including diabetic retinopathy,glaucoma,proliferative vitreoretinopathy,and age-related macular degeneration.Further,we explore the potential of circular RNAs as novel biomarkers and therapeutic targets for the diagnosis and treatment of retinal diseases. | Aneliya Hanineva Karen Sophia Park Joshua J.Wang Margaret M.DeAngelis Michael H.Farkas Sarah X.Zhang | 2022 | Neural Regeneration Research2022，17，9： | 2 |
| 13 | Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases显示文摘 | Sung-Jun Park Faiyaz Ahmad Andrew Philp Keith Baar Tishan Williams Haibin Luo Hengming Ke Holger Rehmann Ronald Taussig Alexandra L. Brown Myung K. Kim Michael A. Beaven Alex B. Burgin Vincent Manganiello Jay H. Chung | 2012 | Cell2012，，3： | 2 |
| 14 | Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis 显示文摘 | Michael MH Furst DE Park GS | 2006 | Arthitis Rheum2006，54，2： | 1 |
| 15 | Exceptional chemical and thermal stability of zeolitic imidazolate frameworks显示文摘 | Sung Park Kyo Ni Zheng Cete Adrien P Choi Jae Yong Huang Rudan Uribe-Romo Femando J Chae Hee K O'Keeffe Michael Yaghi Omar M | 2006 | Proceedings of the National Academy of Sciences2006，103，10： | 1 |
| 16 | Stereotactic Body Radiation Therapy for Locally Advanced and Borderline Resectable Pancreatic Cancer Is Effective and Well Tolerated显示文摘 | Michael D. Chuong Gregory M. Springett Jessica M. Freilich Catherine K. Park Jill M. Weber Eric A. Mellon Pamela J. Hodul Mokenge P. Malafa Kenneth L. Meredith Sarah E. Hoffe Ravi Shridhar | 2013 | International Journal of Radiation Oncology Biology Physics2013，，3： | 1 |
| 17 | A review of fabrication and applications of carbon nanotube film- based flexible electronics显示文摘 | Steve Park Michael Vosguerichian and Zhenan Bao | 2013 | Nanoscale2013，5，： | 1 |
| 18 | The role of alanine in the acute response of Giardia intestinalis to hypo-osmot- ic shock显示文摘 | Jeong H Park Philip J Schofield Michael R Edwards | 1995 | Microbiology1995，141，： | 1 |
| 19 | ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association显示文摘 | Vallerie V. McLaughlin Stephen L. Archer David B. Badesch Robyn J. Barst Harrison W. Farber Jonathan R. Lindner Michael A. Mathier Michael D. McGoon Myung H. Park Robert S. Rosenson Lewis J. Rubin Victor F. Tapson John Varga | 2009 | Circulation2009，，16： | 1 |
| 20 | Isoreticular expansion of metal-organic frameworks with triangular and square building units and the lowest calculated density for porous crystals显示文摘 | Furukawa Hiroyasu Bok Go Yong Ko Nakeun Park Young Kwan Uribe-Romo Femando J Kim Jahenn O'Keeffe Michael Yaghi Omar M | 2011 | Inorganic Chemistry2011，50，： | 1 |
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