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| 1 | 美白牙膏去除牙外源性色斑的八周效果观察显示文摘目的 :评价含有 1%焦磷酸钠、7%三聚硫酸钠、0 .2 4 3 %氟化钠及 10 %高清洁二氧化硅的牙膏减少外源性牙色斑的效果。方法 :采用双盲、分层、二单位平行观察的临床研究方法。根据改良 L obene色斑指数 (L obene stain in-dex m ethod)均数、性别、吸烟习惯将 91名年龄为 18~ 5 5岁的研究对象平衡地分为两组 ,随机地分配使用试验或对照牙膏。于基线、第 4周及第 8周固定由一名检查者完成研究对象的色斑指数测定。结果 :86人完成了该研究。8周临床研究表明 ,使用美白牙膏的研究对象较对照组的牙齿色斑指数均数降低了 3 7.1% (P=0 .0 0 0 1)。结论 :与对照组牙膏相比 ,使用含有 1%焦磷酸钠、7%三聚硫酸钠、0 .2 4 3 %氟化钠及 10 %高清洁二氧化硅的牙膏可以有效地减少牙外源性色斑。 | 胡德渝 庞若愚 佘晓晴 雷德伦 Volpe A R DeVizio W Petrone M E Zhang Y P Chaknis P Miller S Miller J | 1999 | 华西口腔医学杂志1999，17，3： | 7 |
| 2 | Approximations of thermoelastic and visxoelastic control systems 显示文摘 | Burns J A Liu Z Y Miller R E | 1991 | Numer Functional Anal Optim1991，12，： | 2 |
| 3 | Anti-hypertensive drugs in children and adolescents显示文摘Worldwide the prevalence of essential hypertension inchildren and adolescents continues to increase. Tradi-tionally providers have used 'off-label' drugs to treatpediatric hypertension, meaning that rigorous clinicaltrials of these drugs have not been specifically per-formed in pediatric patient populations. Consequentlyproviders have extrapolated dosing, safety and efficacyfrom trials in adults. This practice is sub-optimal as chil-dren demonstrate unique differences in drug metabo-lism and response. Use of unstudied or understudieddrugs increases risk of adverse events and/or can leadto sub-optimal efficacy. Recognizing these concerns,regulatory agencies have created financial incentivesfor industry to conduct pediatric clinical trials. Theseincentives, coupled with the emerging pediatric hyper-tension epidemic, have spurred over 30 clinical trialsof anti-hypertensive drugs over the past 15 years andhave resulted in labeling of 10 new drugs by the UnitedStates Food and Drug Administration for treatment ofhypertension in children and adolescents. Unfortunatelythe financial incentive structures focus on newer drugsand drug classes. Consequently there is now a relativedearth of trial data for older but sometimes commonlyprescribed pediatric antihypertensive drugs. This article reviews recent pediatric antihypertensive drug trials with a focus on trial design and endpoints, drug dosing, safety, efficacy and specific drug indications. We also review the available data and experience for some of the more commonly prescribed, but less well studied 'older' pediatric antihypertensive drugs. | Patricia Y Chu Michael J Campbell Stephen G Miller Kevin D Hill | 2014 | World Journal of Cardiology2014，6，5： | 2 |
| 4 | The effect of excess protein on growth performance and protein metabolism of finishing barrows and gilts显示文摘 | Chen H Y Lewis A J Miller P S | 1999 | Journal of Animal Science1999，77，： | 1 |
| 5 | Limiting heights for gypsum-sheathed cold-formed steel wall studs显示文摘 | Lee Y K Miller T H | 2001 | Practice Periodical on Structural Design and Construction ASCE2001，6，2： | 1 |
| 6 | Production of active chimeric pediocin AcH in Escherichia coli in the absence of processing and secretion genes from the Pediococcus pap operon显示文摘 | Miller K W Schamber R Chen Y | 1998 | Appl Environ Microbiol1998，64，： | 1 |
| 7 | Immune modulation by altered nutrient metabolism:nutritional control of immune-induced growth depression显示文摘 | Cook M E Miller C C Park Y | 1993 | Poult-Sci1993，72，： | 1 |
| 8 | Hyperglycemia increases mitochondrial superoxide in retina and retinal cells 显示文摘 | Du Y Miller CM Kern TS | 2003 | Free Radic Biol Med2003，35，11： | 1 |
| 9 | Integrated Micro-ScanningTunneling Microscope显示文摘 | Xu Y MacDonald N C Miller S A | 1995 | Appl Phys Lett1995，67，16： | 1 |
| 10 | Critical role of inducible nitric ox- ide synthase in degeneration of retinal capillaries in mice with streptozotocirinduced diabetes 显示文摘 | Zheng L Du Y Miller C | 2007 | Diabetologia2007，50，9： | 1 |
| 11 | Costs of clinical mastitis and mastitis prevention in dairy herds显示文摘 | Miller G Y Bartlett P C Lance S E | | 0，，： | 1 |
| 12 | Long-lasting and transmission-blocking activity of antibodies to Plasmodiurn falciparurn elicited in mice by protein conjugates of Pfs25 显示文摘 | Kubler Kielb J Majadly F Wu Y Narum D L Guo C Miller L H Shiloach J Robbins J B and Schneerson R | 2007 | Proceedings of the National Academy of Sciences of the United States of America2007，104，1： | 1 |
| 13 | Costs of dairy cow diseases to producers in Ohio显示文摘 | Miller G Y Dorn C R | 1990 | Prev Vet Med1990，8，： | 1 |
| 14 | Long-range entangled carbon nanotube networks in polycarbonate显示文摘 | Singh S Pei Y Q Miller R | 2003 | Advanced Functional Materials2003，13，11： | 1 |
| 15 | Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction显示文摘 | Ou Y Strege P Miller SM | 2003 | J Biol Chem2003，278，3： | 1 |
| 16 | Genetic improvement of Helicoverpa zea nuclear polyhedrosis virus as a biopesti- cide显示文摘 | Popham H J R Li Y Miller L K | 1997 | Biological Control1997，10，2： | 1 |
| 17 | Nuclear EGFR is required for cisplatin resistance and DNA repair显示文摘 | Hsu SC Miller SA Wang Y | 2009 | Am J Transl Res2009，1，3： | 1 |
| 18 | Transfuse and human immunodeficiency virus infections显示文摘 | Zhao Y Yu M Miller JW | 2002 | J Clin Microbiol2002，40，2： | 1 |
| 19 | Expression and localization of a baculovirus protein phosphatase显示文摘 | Li Y Miller L K | 1995 | J Gen Virol1995，76，： | 1 |
| 20 | Homozygous deletions of p15 and p16 gene in adult T-cell leukemia显示文摘 | HaHa Y Hirama T Miller CW | 1995 | Blood1995，85，： | 1 |
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