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| 1 | Common dental diseases in children and malocclusion显示文摘Malocclusion is a worldwide dental problem that influences the affected individuals to varying degrees. Many factors contribute to the anomaly in dentition, including hereditary and environmental aspects. Dental caries, pulpal and periapical lesions, dental trauma, abnormality of development, and oral habits are most common dental diseases in children that strongly relate to malocclusion. Management of oral health in the early childhood stage is carried out in clinic work of pediatric dentistry to minimize the unwanted effect of these diseases on dentition. This article highlights these diseases and their impacts on malocclusion in sequence. Prevention, treatment, and management of these conditions are also illustrated in order to achieve successful oral health for children and adolescents, even for their adult stage. | Jing Zou Mingmei Meng Clarice S Law Yale Rao Xuedong Zhou | 2018 | International Journal of Oral Science2018，10，2： | 16 |
| 2 | Chitosan hydrogel incorporated with dental pulp stem cell-derived exosomes alleviates periodontitis in mice via a macrophage-dependent mechanism显示文摘Periodontitis is caused by host immune-inflammatory response to bacterial insult.A high proportion of proinflammatory macrophages to anti-inflammatory macrophages leads to the pathogenesis of periodontitis.As stem cell-derived exosomes can modulate macrophage phenotype,dental pulp stem cell-derived exosomes(DPSC-Exo)can effectively treat periodontitis.In this study,we demonstrated that DPSC-Exo-incorporated chitosan hydrogel(DPSC-Exo/CS)can accelerate the healing of alveolar bone and the periodontal epithelium in mice with periodontitis.Gene Ontology(GO)term enrichment analysis showed that treatment with DPSC-Exo/CS ameliorated periodontal lesion by suppressing periodontal inflammation and modulating the immune response.Specifically,DPSC-Exo/CS facilitated macrophages to convert from a pro-inflammatory phenotype to an anti-inflammatory phenotype in the periodontium of mice with periodontitis,the mechanism of which could be associated with miR-1246 in DPSC-Exo.These results not only shed light on the therapeutic mechanism of DPSCExo/CS but also provide the basis for developing an effective therapeutic approach for periodontitis. | Zongshan Shen Shuhong Kuang Yong Zhang Mingmei Yang Wei Qin Xuetao Shi Zhengmei Lin | 2020 | Bioactive Materials2020，5，4： | 14 |
| 3 | CAF-induced placental growth factor facilitates neoangiogenesis in hepatocellular carcinoma显示文摘As a highly malignant tumor,hepatocellular carcinoma(HCC)is the third leading cause of cancer-related deaths worldwide.In most HCC patients,the development of HCC begins with hepatitis,which is followed by fibrosis and cirrhosis before progressing to HCC.Cancer-associated fibroblasts(CAFs),which are generally believed to be derived from activated hepatic stellate cells(HSCs),are highly involved in the development of HCC through the secretion of cytokines and angiogenic factors.The results of our study showed that a considerable number of CAFs highly expressed CD90 and were enriched in HCC tissues.Bioinformatics analysis of the transcriptome of HCC tissues revealed that placental growth factor(PIGF)is significantly correlated with CD90 expression.The isolated primary CAFs and activated HSCs overexpressed PIGF and CD90.In addition,the results of gene expression profiling interactive analysis based on The Cancer Genome Atlas showed that high levels of both PIGF and CD90 are correlated with tumor angiogenesis markers(CD31,CD34,and CD105)and predict poor HCC patient prognosis.In summary,our results suggest that CAFs can generate PIGF and may provide an effective target for CAFs-reguIated neoangiogenesis in HCC. | Zhongjian Liu Mingmei Chen Rongce Zhao Yuan Huang Fei Liu Bo Li Yang Qin | 2020 | Acta Biochimica et Biophysica Sinica2020，52，1： | 5 |
| 4 | Mathematical modeling of fluid flow, heat transfer and inclusion transport in a four strand tundish显示文摘Mathematical simulation was used for trouble-shooting and optimization. By the mathematical simulation, fluid flow and heat transfer of molten-steel in a four-strand tundish of a billet caster under different conditions (bare tundish and tundish with flow control device) were analyzed. The results showed that (1) the tundish with flow control device (FCD) has an important effect on the fluid pattern and temperature distribution; (2) the unsteady solving method was used to model the inclusion motions at different time periods, and it showed that the FCD is advantageous to separate the nonmetallic inclusions. According to the simulation results, the main problem existing in the industry production was found, and some helpful measurements were executed. Consequently, the large nonmetallic inclusions were separated, and the content of total oxygen was reduced. The quality of steel was greatly improved. | Yufeng Wang Guanghua Wen Ping Tang Mingmei Zhu Yuanqing Chen Weizhao Song | 2007 | Journal of University of Science and Technology Beijing2007，14，1： | 4 |
| 5 | Facile shape and size-controlled growth of uniform magnetite and hematite nanocrystals with tunable properties显示文摘Monodispersed magnetite Fe3O4 and hematite α-Fe2O3 nanocrystals have been grown in co-solvents of alcohol and water. Either the shape or the size of the nanocrystals could be easily controlled. Both the phases and nanostructures have been characterized by powder X-ray diffraction patterns and electron microscopy. The magnetic and catalytic properties of these products were investigated and compared with each other. The obtained results clearly demonstrate that these iron oxide nanocrystals are soft ferromagnetic at room temperature and α-Fe2O3 has a more effective catalytic property on the thermal decomposition of ammonium perchlorate than Fe3O4. Based on the experimental data, it is proposed that the magnetic and catalytic properties of these nanocrystals are dependent not only on the size and shape, but also on the surface structure of the nanocrystals. The nanoplates with significant anisotropic nanostructure demonstrate a highly enhanced performance as compared to nanoparticles. | CHEN LiQiao LIU WeiPing CHEN JiaLin YANG XianFeng LIU Jia FU XiongHui WU MingMei | 2011 | Science China Chemistry2011，54，6： | 4 |
| 6 | An Fe-N/S-C hybrid electrocatalyst derived from bimetal-organic framework for efficiently electrocatalyzing oxygen reduction reaction in acidic media显示文摘Heteroatoms doped Fe-N-C electrocatalysts have been widely acknowledged as one of the most promising candidates to replace Pt-based materials for electrocatalyzing oxygen reduction reaction(ORR).However,the complicated synthesis method and controversial catalytic mechanism represent a substantial impediment as of today.Herein,a very facile strategy to prepare Fe-N/S-C hybrid through pyrolyzing Zn and Fe bimetallic MOFs is rationally designed.The electrocatalytic ORR performance shows a volcanotype curve with the increment of added Fe content.The half-wave potential(E1/2) for ORR at optimized Fe-N/S-C-10%(10%=n(Fe)/(n(Fe)+n(Zn)),n(Fe) and n(Zn) represent the moles of Fe2+ and Zn2+ in the precursors,respectively) shifts significantly to the positive direction of 19.6 mV with respect to that of Pt/C in acidic media,as well as a high 4 e selectivity and methanol tolerance.After 10,000 potential cycles,E1/2 exhibits a small negative shift of-27.5 mV at Fe-N/S-C-10% compared favorably with Pt/C(~141.0 mV).This can be attributed to:(ⅰ) large specific surface area(849 m^(2)/g) and hierarchically porous structure are favorable for the rapid mass transfer and active sites exposure;(ⅱ) the embedded Fecontaining nanoparticles in porous carbon are difficult to be moved and further agglomerated during the electrochemical accelerated aging test,further improving its stability;(ⅲ) there exist small Fecontaining nanoparticles,uniformly doped N and S,abundant Fe-N as efficiently active sites.This work represents a breakthrough in the development of high-efficient non-precious-metal catalysts(NPMCs)to address the current Pt-based electrocatalysts challenges. | Shuqin Song Mingmei Wu Junwei Chen Zhuohua Mo Rui Chen Kun Wang Tongwen Yu | 2021 | Journal of Energy Chemistry2021，30，1： | 2 |
| 7 | Differences in Chlorophyll Fluorescence Parameters, Yield and Its Components Between Different Genotypes of Wheat Under Waterlogging Conditions at Anthesis显示文摘Waterlogging is one of the most factors limiting wheat production in the middle and lower reaches of the Yangtze River Plain of China,especially in the middle and late stages of wheat.Wheat varieties‘Jingmai102’(JM102)and‘Yangmai158’(YM158)were planted to study the dynamic changes of photosynthetic characteristics in flag leaf and the influence of waterlogging at anthesis on the yield and components and dry matter accumulation and remobilization of winter wheat in above ground.The results showed that the SPAD values slightly increased at 1 day after anthesis(d),and then kept decreasing with the increase of waterlogging time.The decrease in SPAD value was more remarkably in YM158 than that in JM102.As for the chlorophyll fluorescence parameters,the photochemical efficiency(Fv/Fm),potential activity(Fv/Fo)of photosystem II,and electronic transmission(Fm/Fo)on photosystem II increased first and then decreased with the increase of waterlogging days after anthesis.The quantum ratio of heat dissipation(Fo/Fm)had a tendency opposite to that of Fv/Fm,and the change range of JM102 was lower than that of YM158.For the grain yield and components,waterlogging at anthesis decreased the dry weight of single stem,grain yield,1 000-kernel weight,spikelet per panicle,and harvest index,and the reduction of JM102 was smaller than that of YM158.As for the accumulation and remobilization of dry matter,the accumulation of dry matter after anthesis decreased significantly under waterlogging condition(WL),and the reduction of JM102 was smaller than that of YM158.In conclusion,waterlogging at anthesis significantly affected the photosynthetic characteristics,yield and components in both varieties,but different varieties exhibited different tolerances to waterlogging stress and YM158 was more sensitive to water stress than JM102. | Mingmei WEI Xiaoyan WANG | 2019 | Agricultural Biotechnology2019，8，4： | 2 |
| 8 | Study on the optimization of the combined blown converter process in Chongqing Iron and Steel Company显示文摘The effects of lance height and bottom blown flowrate on the mixed time,the splashing amount,the penetrating depth,and the level fluctuation of an 85 t combined blown converter have been studied using a water model.The results show that the maximal stirring energy is provided to the bath at the top lance height of about 50-100 mm.When the top lance height is in the range of 90- 110 mm,the splashing amount caused by the top jet can reach the maximal value.The appropriate operational parameters of Chongqing Iron and Steel Company(CISC)converter have been established that the top lance height is 1600-1760 mm and the bot- tom blowing flowrate is 240-480 Nm^3/h in the primary phase of a heat,1100-1300 mm and 160-200 Nm^3/h in the second phase,and 1040-1120 mm and 200-350 Nm^3/h in the end phase.Also,the trial shows that the metallurgical result of the studied blow pattern is better than that of the former pattern.At the starting 3-4 min of a heat,the strong splashing is eliminated. | Ping Tang Yangyang Yu Guanghua Wen Mingmei Zhu Liang Zhou Yiju Long Qing Liang | 2008 | Journal of University of Science and Technology Beijing2008，15，1： | 2 |
| 9 | Load forecasting using support vector machines:a study on EUNITE competition 2001显示文摘 | Chen Bojuen Chang Mingmei | 2004 | IEEE Trans on Power Systems2004，19，4： | 1 |
| 10 | Small interfering RNA-mediated inhibition of hepatitis G virus gene expression in human hepatoma cell Huh-7显示文摘The RNA interference (RNAi) phenomenon is a recently observed process in which the introduction of a double-stranded, small interfering RNA (siRNA) into a cell causes the specific degradation of a homologous single-stranded RNA. It represents an exciting new technology that could have therapeutic applications for the treatment of viral infections. Since hepatitis G virus (HGV) genome is a positive-sense single-stranded RNA, the replication of HGV does not lead to an integrated DNA genome, suggesting a particularly attractive target for RNAi study that could eliminate viral RNA from infected cells. The eukaryotic expression vector pVAX.EH containing the cDNA sequences of the entire HGV structural genes and hygromycin resistance gene downstream from the encephalomyocarditis virus (ECMV) internal ribosome entry site (IRES)was constructed and transfected into human hepatoma cell Huh-7. The modified cleavage products of the structural proteins of HGV expressed in hygromycin-resistant cell line Huh-7-EH were confirmed by RT-PCR and Western blot methods. Two specific HGV E2 siRNAs (1-E2siRNA, 2-E2 siRNA) synthesized with T7 RNA polymerase by transcription in vitro were transfected into the Huh-7-EH cells. With the analyses of Western blot and the formation of hygromycin-resistant colonies, the inhibitions of expression of HGV structural protein by two HGV E2siRNAs were detected and found lasting at least one week. The inhibition of 2-E2 siRNA was stronger and only 1% of the cells treated with 2-E2 siRNA formed hygromycin-resistant colonies.These results support that specific HGV 2-E2 siRNAs mediate the degradation of mRNA spanning from HGV structural gene cDNA to hygromycin resistance gene in a majority of cells. In conclusion, the Huh-7-EH cells expressing HGV structural proteins stably can be used as a cell model for studying the replication of HGV and RNAi and the enlargement of RNAi may exist, in mammalian cells. | CAO Mingmei REN Hao ZHAO Ping PAN Wei ZHAO Lanjuan QI Zhongtian | 2005 | Science China(Life Sciences)2005，48，1： | 1 |
| 11 | Synthesis of Eu^3+ doped Calcium and Strontium Carbonate Phosphors at Room Temperature显示文摘 | Pan Yuexiao Wu Mingmei Su Qiang | 2003 | Mater Res Bal2003，38，910： | 1 |
| 12 | Silicon Nitride Etch via Oxidation Reaction in Fluorocarbon/Oxygen Plasma:A First-Principle Study显示文摘Conducting all-in-one etch process for 3D-NAND fabrication requires close etch rate(E/R)for SiO2 and Si3N4;however,to attain comparable and high etch rate for both materials is challenging.In this work,we performed first-principle studies on the etching mechanism of Si3N4 in fluorocarbon/oxygen plasma.The feasibility of using fluorocarbon/oxygen plasma to etch Si3N4 while attaining close E/R to SiO2 through the complementary nitride to oxynitiride(SiOxNy)transformation has been identified.Such transformation involves two stages:N atom elimination and Si-O bond formation.By modeling the essential chemical reactions on the Si3N4 surface,we shed light upon the underlying mechanisms behind both stages.We simulated the N-elimination reactions involving the formation and desorption of NO and FNO molecules as well as the substitution with F atoms.We found that N atoms can be eliminated by forming NO molecules,especially with the assistance of F-substitution in Si-N bond breaking.The predicted O-additive energies indicates that forming SiOxNy structure after N-elimination is possible.Following that,the dependency of chemistries favoring either high E/R or active SiOxNy formation on the fluorocarbon/oxygen ratio was discussed.We hope that the work will build a foundation for future studies on pursuing all-in-one ON etch process via the surface modifications. | Yu-Hao Tsai Du Zhang Mingmei Wang | 2018 | Journal of Microelectronic Manufacturing2018，1，1： | 1 |
| 13 | Inhibition of EGFP expression by siRNA in EGFP-stably expressing Huh-7 cells显示文摘 | Mingmei Cao Hao Ren | 2004 | J Virol2004，119，： | 1 |
| 14 | Comparative investigation on synthesis and photoluminescence of YAG: Ce phosphor 显示文摘 | Pan Yuexiao Wu Mingmei Su Qiang | 2004 | Materials Science and Engineering B2004，106，： | 1 |
| 15 | Tailored photoluminescence of YAG:Ce phosphor through various methods显示文摘 | Mingmei Wu Qiang Su | 2000 | Journal of Physics and Chemistry of Solids2000，65，： | 1 |
| 16 | Comparative investigation on synthesis and photoluminescence of YAG : Ce phosphor显示文摘 | Pan Yuexiao Wu Mingmei Su Qiang | | Materials Science and Engineering B0，106，3： | 1 |
| 17 | Efficient removal for multiple pollutants via Ag_(2)O/BiOBr heterojunction:A promoted photocatalytic process by valid electron transfer pathway显示文摘Multiple pollutants including pathogenic microorganism contaminations and emerging organic contaminations(EOCs)have shown a growing threat to the environment,especially the natural waters.However,the control and removal of pathogenic microorganism contaminations and EOCs have been greatly limited since limited knowledge of their environmental behaviors.Thus,a novel and efficient photocatalyst Ag_(2)O/BiOBr heterojunction was synthesized and used for removal of multiple pollutants including Escherichia coli(E.coli),Staphylococcus aureus(S.aureus),tetracycline and acetaminophen under visible light.The results showed that there were valid electron transfer pathways between BiOBr and Ag_(2)O,the main electron transfer direction was the BiOBr to Ag_(2)O.Photo-generated electrons were stored in Ag_(2)O and thus separation efficiency between holes and photo-generated electrons was obviously enhanced.Active oxygen species were highly produced and eventually end up with the high efficiency of removal of multiple pollutants.For Ag_(2)O/BiOBr with Ag_(2)O content at 3%(the best performance)under visible light,log decrease of E.coli was 7.16(removal efficiency was 100%)in 120 min,log decrease of S.aureus was 7.23(removal efficiency was 100%)in 160 min,C/C0 of tetracycline was 0.06 in 180 min,C/C0 of acetaminophen was 0.17 in 180 min.This work could provide a promising candidate in the actual contaminated natural waters for cleaning multiple pollutants. | Zhiruo Zhou Yanan Li Mingmei Li Yi Li Sihui Zhan | 2020 | Chinese Chemical Letters2020，31，10： | 1 |
| 18 | Tailored photoluminescence of YAG : Ce phosphor through various methods显示文摘 | Pan Yuexiao Wu Mingmei Su Qiang | 2004 | J Phys and Chem of Sohds2004，65，5： | 1 |
| 19 | Preparation of stable CaS: Eu^2+ ,Tm^3+ phosphor显示文摘 | Guo Chongfeng Chu Benli Wu Mingmei | 2003 | J Rare Earths2003，21，5： | 1 |
| 20 | Oxide coating for alkaline earth sulfide based phosphor 显示文摘 | Guo Chongfeng Chu Benli Wu Mingmei | 2003 | J Luminescesce2003，105，： | 1 |
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