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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Atomic bonding of precipitate and phase transformation of Al-Cu-Mg alloy 显示文摘 | CAO Y J HOU X H MO Q F | 2007 | J Alloys Compd2007，441，： | 1 |
| 3 | Utilization of a metabolic un- coupler,3 ,3' ,4' ,5-tetrachlorosalicylanilide (TCS) to re- duce sludge growth in activated sludge culture 显示文摘 | Chen G H Mo H K Liu Y | 2002 | Water Res2002，36，8： | 1 |
| 4 | High growth of SWNTs and MWNTs from C2H2 decomposition over Co-Mo/MgO catalysts显示文摘 | SHAJIHAN M MO Y H FAZLE KIBRIA A K M | 2004 | Carbon2004，42，： | 1 |
| 5 | Kimuras disease:the CT and MRI characteristics in fifteen cases显示文摘 | Zhang R Ban X H Mo Y X | 2011 | Eur J Radioi2011，80，2： | 1 |
| 6 | Research on High Performance Concrete-Filled Steel Tube Columns Structure Experiments for Guangzhou Xita Project 显示文摘 | Yang Y B Liang S Mo H H | 2009 | Key Engineering Materials2009，，405406： | 1 |
| 7 | Implementation of a clinical pathway in primary spontaneous pneumothorax patients treated by wedge resection surgery显示文摘 | Mo J Oh H Ahn Y | 2010 | Clin Nurse Spec2010，24，6： | 1 |
| 8 | A new species of Dactylella and its telemorph 显示文摘 | MO M H ZHOU W HUANG Y | 2005 | Mycotaxon2005，91，： | 1 |
| 9 | Numerical simulationof the NOx emissions in a 1,000,MW tangentially firedpulverized-coal boiler:Influence of the multi-group arrangementof the separated over fire air 显示文摘 | Zhou H Mo G Y Si D B | 2011 | Energy &Fuels2011，25，5： | 1 |
| 10 | Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition显示文摘 | LI H B YANG Y R MO Z J | 2015 | Braz J Med Biol Res2015，48，5： | 1 |
| 11 | The role of autoregressive conditional skewness and kurtosis in the estimation of conditional VaR显示文摘 | Bali T G Mo H Tang Y | | 0，，02： | 1 |
| 12 | Polycyclic aromatic hydrocarbons and phthalic acid esters in the soil-radish(Raphanus sativus) system with sewage sludge and compost application显示文摘 | Cai Q Y Mo C H Wu Q T | 2008 | Bioresource Technology2008，99，： | 1 |
| 13 | MMSE-based joint source and relay precoding design for amplify-and forward MIMO relay net- works显示文摘 | Mo R H Chew Y H | 2009 | IEEE Transactions on Wireless Communica- tions2009，8，9： | 1 |
| 14 | Accumulation of phthalic acid esters in water spinach (Ipomoea aquatica) and in paddy soil 显示文摘 | CAI Q Y MO C H WU Q T | 2006 | Bulletin of Environment Contamination and Toxicology2006，77，： | 1 |
| 15 | Inhibition by epigallocatechin gallate of CoC12-induced apoptosis in rat PC12 cells 显示文摘 | Jung J Y Mo H C Yang K H | 2007 | Life Sci2007，80，15： | 1 |
| 16 | Human papillomavirus and the long-term risk of cervical neoplasia显示文摘 | van-der-Graaf Y Mo lijn A Doo rnewaar d H | 2002 | Am J Epidemiol2002，156，2： | 1 |
| 17 | Structural transformation of carbon nanotubes to silicon carbide nanorods or microcrystals by the reaction with different silicon sources in rf induced CVD reactor显示文摘 | Mo Y H Shajaban M D Lee Y S | 2004 | Synthetic Met2004，140，7： | 1 |
| 18 | Polycyclic aromatic hydrocarbons and phthalic acid esters in the soil-radish (Raphanus sativus) system with sewage sludge and compost application 显示文摘 | CAI Q Y MO C H WU Q T | 2008 | Bioresource Technology2008，99，： | 1 |
| 19 | Effects of pulsed electric fields on physicochemical properties of soybean protein isolates显示文摘 | Li Y Q Chen Z X Mo H Z | 2007 | Lebensmittel-wissenschaft and Technologie2007，40，7： | 1 |
| 20 | Synthesis of carbon nanotubes over nickel-iron catalysts supported on alumina under controlled conditions 显示文摘 | Kibria AKMF Mo Y H Nahm K S | 2001 | Catalyst Letters2001，71，34： | 1 |
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