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| 1 | 男性迟发性性腺功能减退症的检查、治疗和监测:国际男科学会(ISA)、国际老年男性研究会(ISSAM)、欧洲泌尿外科学会(EAU)、欧洲泌尿外科学院(EAA)和美国男科学会(ASA)联合推荐显示文摘简介
人口学资料明确显示:老年人口占总人口的百分率正逐年增加。当前,有关老年男性雄激素缺乏的问题逐渐成为令人感兴趣、但又充满争议的世界性话题。已经有横向和纵向的研究资料表明,随着年龄增大,成年男子的雄激素水平逐渐降低, | Wang C Nieschlage E Swerdloff R Behre HM Hellstrom WJ Gooren LJ Kaufman JM Legros JJ Lunenfeld B Morales A Morley JE Schulman C Thompson IM Weidner W Wu FCW 伍学焱(翻译) | 2011 | 国际生殖健康/计划生育杂志2011，30，1： | 8 |
| 2 | Hepatitis C eradication with sofosbuvir leads to significant metabolic changes显示文摘AIM To assess the effect of sofosbuvir(SOF) based regimens on glycemic and lipid control.METHODS This is a retrospective analysis of hepatitis C virus(HCV)-infected patients treated and cured with a SOF regimen [SOF/ribavirin/interferon, SOF/simeprevir, or SOF/ledipasvir(LDV) ± ribavirin] from January 2014 to March 2015. Patients with hemoglobin A1C(HbA1C) and lipid panels within six months before and six months after therapy were identified and included in our study. Due to the known hemolytic effect of ribavirin, HbA1C was obtained a minimum of three months post-treatment for the patients treated with a ribavirin regimen. Medical history, demographics, HCV genotype, pre-therapy RNA, and liver biopsies were included in our analysis. The patients who started a new medication or had an adjustment of baseline medical management for hyper-lipidemia or diabetes mellitus(DM) were excluded from our analysis.RESULTS Two hundred and thirty-four patients were reviewed, of which 60 patients met inclusion criteria. Sixty-three point three percent were male, 26.7% were Caucasian, 41.7% were African American and 91.7% were infected with hepatitis C genotype 1. Mean age was 60.6 ± 6.7 years. Thirty-nine patients had HbA1C checked before and after treatment, of which 22 had the diagnosis of DM type 2. HbA1C significantly decreased with treatment of HCV(pretreatment 6.66% ± 0.95% vs posttreatment 6.14% ± 0.65%, P < 0.005). Those treated with SOF/LDV had a lower HbA1C response than those treated with other regimens(0.26% ± 0.53% vs 0.71% ± 0.83%, P = 0.070). Fifty-two patients had pre- and post-treatment lipid panels; there was a significant increase in low-density lipoprotein(LDL) and total cholesterol(TC) after treatment(LDL: 99.5 ± 28.9 mg/dL vs 128.3 ± 34.9 mg/dL, P < 0.001; TC: 171.6 ± 32.5 mg/dL vs 199.7 ± 40.0 mg/dL, P < 0.001). Pretreatment body-mass index(BMI) did not differ from post-treatment BMI(P = 0.684). CONCLUSION Eradication of HCV with a SOF regimen resulted in a significant drop in HbA1C and an increase in LDL and TC post therapy. | Amilcar L Morales Zachary Junga Manish B Singla Maria Sjogren Dawn Torres | 2016 | World Journal of Hepatology2016，8，35： | 2 |
| 3 | Implications of using two low-power continuous-wave lasers for polishing显示文摘Laser polishing is widely employed to reduce the surface roughness of products with complex geometries.Traditional laser polishing techniques use a single high-power Gaussian beam to melt and smooth a thin layer of surface material.However,the reliance on high power lasers can present practical challenges such as minimizing surface evaporation or reducing overall cost.In this work,we combined two identical low-power laser beams with a spatial offset in between them to construct an elliptical beam.By changing the spatial offset,combined beams with different lengths along the major axis can be created.We observe over 20%improvement in line roughness reduction using this approach compared to a single Gaussian laser beam with the same total power.Additionally,both experiment and simulation results suggest such improvement is because this dual-laser set-up can create a longer molten pool compared to a single laser. | Wenxuan Zhang Kiwan Wong Miguel Morales Carlos Molpeceres Craig B Arnold | 2020 | International Journal of Extreme Manufacturing2020，2，3： | 2 |
| 4 | Organoclays:Properties,preparation and applications显示文摘 | PATVA L B MORALES A R DIAZ F R V | 2008 | Applied Clay Science2008，42，12： | 1 |
| 5 | Eelctrochemical treatment applied to food-processing industrial wastewatcr显示文摘 | D(I)AZ C B MORALES G R C(O)RDOBA L (A) | 2006 | Industrial & Engineering Chemistry Research2006，45，： | 1 |
| 6 | Horizontal transmissible protection against myxomatosis and rabbit haemorrhagic disease by using a recombinant myxoma virus显示文摘 | BARCENA J MORALES M VAZQUEZ B | 2000 | J Virol2000，74，3： | 1 |
| 7 | Effects of manganese oxide promoter on the CO and H2adsorption properties of titania-supported cobalt Fischer-Tropsch catalysts显示文摘 | MORALES F SMIT E GROOT F M F VISSER T WECKHUYSEN B M | 2007 | J Catal2007，246，1： | 1 |
| 8 | Clinical course and outcome of patients admitted to an ICU for status asthmatics显示文摘 | Afessa B Morales I Cury JD | 2001 | Chest2001，120，5： | 1 |
| 9 | 显示文摘 | Morales L Allub R Alascio B | 2005 | Phys Rev B2005，72，13： | 1 |
| 10 | In situ synthesis of magnetic multiwalled carbon nanotube composites for the clean - up of ( fluoro ) quinolones from human plasma prior to ultrahigh pressure liquid chromatography analysis 显示文摘 | Morales -Cid G Fekete A Simonet B M | 2010 | Anal Chem2010，82，： | 1 |
| 11 | Conjugated linoleic acid(cla)during last week of gestation and lactation alters colostrum and milk fat composition and performance of reproductive sows显示文摘 | Cordero G Isabel B Morales J | 2011 | Anim Feed Sci Tech2011，168，34： | 1 |
| 12 | Elevated linezolid resistance in clinical cfrpositive Staphylococcus aureus isolates is associated with cooccurring mutations in ribosomal protein L3显示文摘 | Locke J B Morales G Hilgers M | 2010 | Antimicrob Agents Chemother2010，54，12： | 1 |
| 13 | Lym-phocyte subpopulations of regional lymph nodes in human colon and gas- tric adenocarcinomas 显示文摘 | Lores Vazquez B Pacheeo Carracedo M Oliver Morales J | 1996 | Cancer Immunol Immunother1996，42，6： | 1 |
| 14 | The mechanical properties,dimensional tolerance and microstructural characterization of micro-molded ceramic and metal components显示文摘 | GARINO T J MORALES A M BOYCE B L | 2004 | Microsystem Technologies2004，，10： | 1 |
| 15 | Prognostic factors,clinicalcourse and hospital outcome of patients with chronic obstructive pulmonary disease admitted to an intensive care unit for respiratory failure显示文摘 | Afessa B Morales I J Scanlon P D | | 0，，： | 1 |
| 16 | Prognostic factors, clinical course, and hospital outcome of patients with chronic obstructive pulmonary disease admitted to an intensive care unit for acute respiratory failure显示文摘 | AFESSA B MORALES IJ SCANLON PD | 2002 | Crit Care Med2002，30，7： | 1 |
| 17 | Evaluation and characterization of Mn-Cu mixed catalysts supported on TiO2 and ZrO2 for ethanol total oxidation显示文摘 | Morales M Barbero B P Lopez T | | 0，，： | 1 |
| 18 | Neuronal organi- zation and cell interactions of the cat stellate ganglion 显示文摘 | Nozdrachev AD Jim6nez B Morales MA | 2002 | A uton Neurosei2002，95，12： | 1 |
| 19 | Quantitative detection of methylated ESR1 and 14-3-3-sigma gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy显示文摘 | Martínez-Galán J Torres B Del Moral R | 2008 | Cancer Biol Ther2008，7，6： | 1 |
| 20 | CTACK,a skin-associated chemokine that preferentially attracts skin-homing memory T cells显示文摘 | Morales J Homey B Vicari A P | 1999 | Proc Natl Acad Sci USA1999，96，14： | 1 |
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