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| 1 | Lipopolysaccharide Enhances the Production of Nicotine-Induced Prostaglandin E2 by an Increase in Cyclooxygenase-2 Expression in Osteoblasts显示文摘以前的研究显示了那脂肪的多糖(LPS ) 在匾的 fromGram 否定的细菌导致前列腺素 E_2 (PGE_2 ) 的版本,它在吸烟的 periodontitis,和那棵烟草支持牙槽的骨头再吞可能是为 periodontitis 的发展和严厉的一个重要风险因素。我们在碱性磷酸酶(ALPase ) 上决定了烟碱 andLPS 的效果活动, PGE_2 生产,和表示 ofcyclooxygenase (COX-1, COX-2 ) , PGE_2 受体 Ep1-4,和在人的 osteoblastic Saos-2 房间的巨噬细胞殖民地刺激因素(M-CSF ) 。房间与 10 ~ 是有教养的(-3) M 烟碱面对 0, 1,或 10 μ g /ml LPS,或与 LPS 独自一个。ALPase 活动独自在与烟碱或 LPS 有教养的房间减少了,并且在与烟碱和 LPS 有教养的那些进一步减少了,而 PGE_2 生产显著地在前者增加了并且在后者进一步增加了。由自己,烟碱没影响 COX-1, COX-2,任何 PGE_2 受体,或 M-CSF 的表示,但是烟碱和 LPS 什么时候是现在, COX-2 的表示, Ep3, Ep4,和 M-CSF,显著地增加。10 ~ 的同时的增加(-4) M 消炎痛在 ALPase 活动, PGE_2 生产,和 M-CSF 表示消除了烟碱和 LPS 的效果。proteinkinase A 的 Phosphorylation 在与烟碱和 LPS 有教养的房间高。这些结果建议 LPS 由造骨细胞的 COX-2 表示的增加提高导致烟碱的 PGE_2 的生产, thatnicotine-LPS-induced PGE_2 首先在 autocrine orparacnne 模式与造骨细胞 Ep4 受体交往,并且 nicotine-LPS-induced PGE_2 然后减少 ALPase 活动和 increasesM-CSF 表示。 | Maiko SHOJI Natsuko TANABE Narihiro MITSUI Naoto SUZUKI Osamu TAKEICHI Tomoko KATONO Akira MOROZUMI Masao MAENO | 2007 | Acta Biochimica et Biophysica Sinica2007，39，3： | 9 |
| 2 | Isolated splenic vein thrombosis secondary to splenic metastasis: A case report显示文摘A 49-year-old, previously healthy woman sought treatment for abdominal pain. Colonoscopy revealed ascending colon cancer. Computed tomography and angiography showed splenic metastasis and thrombosis extending from the splenic vein to the portal vein. She underwent right hemicolectomy, splenectomy, and distal pancreatomy. Histological findings showed no malignant cell in the splenic vein which was filled with organizing thrombus. We postulate the mechanism of splenic vein thrombosis in our case to be secondary to the extrinsic compression of the splenic vein by the splenic metastasis or by the inflammatory process produced by the splenic metastasis. In conclusion, we suggest that splenic metastasis should be added to the list of differential diagnosis which causes splenic vein thrombosis. In the absence of other sites of neoplastic disease, splenectomy seems to be the preferred therapy because it can be performed with low morbidity and harbors the potential for long-term survival. | Kunihiko Hiraiwa Kyoei Morozumi Hiroshi Miyazaki Keiichi Sotome Akio Fu-rukawa Makoto Nakamaru Yoichi Tanaka Hisami Iri | 2006 | World Journal of Gastroenterology2006，12，40： | 5 |
| 3 | Anterior decompression and fusion versus laminoplasty for cervical myelopathy caused by soft disc herniation:a prospective multicenter study显示文摘 | Koakutsu T Morozumi N Ishii Y | 2010 | J Orthop Sci2010，15，1： | 1 |
| 4 | Growth and structures of surface disturbances of a round liquid jet in a coaxial airflow 显示文摘 | Yoshio Morozumi Jun Fukai | 2004 | Fluid Dynamics Research2004，34，： | 1 |
| 5 | Emergence of macrolide resistant Mycoplasma pneumoniae with a 23S rRNA gene mutation显示文摘 | Morozumi M Hasegawa K Kobayashi R | 2005 | Antimicrob Agents Chemother2005，49，23： | 1 |
| 6 | Increased macrolide resist- ance of Mycoplasma pneumoniae in pediatric patients with communi- ty-acquired pneumonia显示文摘 | Morozumi M Iwata $ Hasegawa K | 2005 | Antimicrob Agents Chemother2005，52，1： | 1 |
| 7 | 采用高热导率技术实现电动汽车和混合电动汽车用的高功率密度IGBT模块显示文摘应用于EV/HFV(电动汽车和混合电动汽车)转换系统的IGBT模块,要求其提高功率密度,以能达到缩小系统体积的目标。为了达到这个目标,我们研发了采用高热导工艺的新型的高功率密度的6-型(6-pack)IGBT模块。采取的创新措施有:采用直接冷却系统以消除热脂的热阻;优化了散热器和液体套管的设计;绝缘衬底不采用通常使用的Al_2O_3(氧化铝),而采用了热导率比Al_2O_3高的Si_3N_4(氮化硅);开发了新型焊接材料。研发的新型IGBT模块能用于EV/HFV转换系统的可能性是非常大的。 | Shinichiro Adachi Fumio Nagaune Hiromichi Gohara Takahisa Hitachi Akira Morozumi Akira Nishiura 郑鹏洲(译) | 2013 | 电力电子2013，，3： | 1 |
| 8 | Nitroblue tetrazolium reduction by neutrophils of newborn foals, adult horses, and a foal infected with Rhodococcus (Corynebacterium) equi 显示文摘 | Morozumi Y Higaskiyama S | 1985 | J pn J Vet Sci1985，，48： | 1 |
| 9 | slip system in magnesium显示文摘 | QBARA T YOSHINGA H MOROZUMI S | 1973 | Acta Metallurgica1973，21，7： | 1 |
| 10 | A comparative clinical study of macrolide sensitive and macrolide -resistant Mycoplasma pneumoniae infections in pediatric patients 显示文摘 | Matsubara K Morozumi M OkadaT | 2009 | J Infect Che- mother2009，15，6： | 1 |
| 11 | Increased macrolide resistance of Mycoplasma pneumoniae in pediatric patients with community - acquired pneumonia 显示文摘 | Morozumi M Iwata S Hasegawa K | 2008 | Antimicrab Agents Chemother2008，52，1： | 1 |
| 12 | A comparative clinical study of macrolide-sensitive and macrolide-resistant Mycoplasma pneumoniae infections in pediatric patients显示文摘 | Matsubara K Morozumi M Okada T | 2009 | J Infect Chemother2009，15，38： | 1 |
| 13 | Cloning, expression, and polymorphisms of natural killer cell receptor NCR1 in pigs 显示文摘 | Jozaki K Shinkai H Morozumi T | 2010 | Anita \Biotechnol2010，21，3： | 1 |
| 14 | Effect of carbon-fiber brushes on conductive heat transfer in phase change materials显示文摘 | FUKAI J HAMADA Y MOROZUMI Y | 2002 | International Journal of Heat and Mass Transfer2002，45，24： | 1 |
| 15 | Characterization and Induction of the Activity of 1-Aminoeyelopropane-1-Carboxylate Oxidase in the Wounded Mesocarp Tissue of Cueurbita maxima 显示文摘 | Hyodo H Hashimoto C Morozumi S | 1993 | Plant and Cell Physiology1993，34，5： | 1 |
| 16 | Effect of carbon-fiber brushes on conductive heat transfer in phase change materials 显示文摘 | FUKAI J HAMADA Y MOROZUMI Y | 2002 | International Journal of Heat and Mass Transfer2002，45，24： | 1 |
| 17 | Increased macrolideresistance o{ Mycoplasma pneumoniae in pediatric patients with community acquired pneumonia显示文摘 | Morozumi M Iwata S Hasegawa K | 2008 | Antimierob Agents Chemother2008，52，34： | 1 |
| 18 | Emergence of macrolide-resistantMycoplasma pneumoniae with a 23S Rrna gene mutation显示文摘 | Morozumi M Hasegawa K Kobayashi R | 2005 | Antimicrob Agents Chemother2005，49，： | 1 |
| 19 | Comprehensive detection of causative pathogens using real-time PCR to diagnose pediatric community-acquired pneumonia 显示文摘 | Hamano-Hasegawa K Morozumi M Nakayama E | 2008 | J Infect Chemother2008，14，6： | 1 |
| 20 | Improvement of thermal characteristics of latent heat thermal energy storage units using carbon fiber brushes:experiments and modeling显示文摘 | FUKAI J HAMADA Y MOROZUMI Y | 2003 | International Journal of Heat and Mass Transfer2003，46，18： | 1 |
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