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3篇 您的检索式:作者名="Nφjgaard"
    题名 作者 年代 出处 被引量
1Does glyceryl nitrate prevent post-ERCP pancreatitis? A prospective,randomized,double-blind,placebo-controlled multicenter trial显示文摘Nφjgaard C Hornum M Elkjaer M 0,,06:1
2Pharmacological approach to acute pancreatitis显示文摘The aim of the present review is to summarize the current knowledge regarding pharmacological prevention and treatment of acute pancreatitis (AP) based on experimental animal models and clinical trials. Somatostatin (SS) and octreotide inhibit the exocrine production of pancreatic enzymes and may be useful as prophylaxis against Post Endoscopic retrograde cholangiopancreatography Pancreatitis (PEP). The protease inhibitor Gabexate mesilate (GM) is used routinely as treatment to AP in some countries, but randomized clinical trials and a meta-analysis do not support this practice. Nitroglycerin (NGL) is a nitrogen oxide (NO) donor, which relaxes the sphincter of Oddi. Studies show conflicting results when applied prior to ERCP and a large multicenter randomized study is warranted. Steroids administered as prophylaxis against PEP has been validated without effect in several randomized trials. The non-steroidal anti-inflammatory drugs (NSAID) indomethacin and diclofenac have in randomized studies showed potential as prophylaxis against PEP. Interleukin 10 (IL-10) is a cytokine with anti-inflammatory properties but two trials testing IL-10 as prophylaxis to PEP have returned conflicting results. Antibodies against tumor necrosis factor-alpha (TNF-α) have a potential as rescue therapy but no clinical trials are currently being conducted. The antibiotics beta- lactams and quinolones reduce mortality when necrosis is present in pancreas and may also reduce incidence of infected necrosis. Evidence based pharmacological treatment of AP is limited and studies on the effect of potent anti-inflammatory drugs are warranted.Ulrich Christian Bang Synne Semb Camilla Nφjgaard Flemming Bendtsen 2008World Journal of Gastroenterology2008,14,19:10
3Serumlevels of YKL-40 increases in patients with acute myocardial infarction 显示文摘NφJGAARD C HOST N B CHRISTENSEN I J 2008Coron Artery Dis2008,19,4:1
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