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| 1 | Octreotide ameliorates gastric lesions in chronically mild stressed rats显示文摘AIM:To evaluate the effect of chronic mild stress(CMS) on the emergence of gastric ulcers and possible modulation by octreotide,a synthetic somatostatin analogue. METHODS:Adult male Wistar rats were subjected to nine different unpredictable random stress procedures for 21 d,a multifactorial interactional animal model for CMS.Octreotide was administered daily for 21 d at two dose levels(50 and 90μg/kg)before exposure to stress procedure.Macro-and microscopical assessments were made,in addition to quantification of plasma corticosterone and gastric mucosal inflammatory,oxidative stress, and apoptotic biomarkers. RESULTS:Exposure to CMS elevated plasma corticosterone(28.3±0.6μg/dL,P=0.002),an event that was accompanied by gastric lesions(6.4±0.16 mm,P=0.01) and confirmed histopathologically.Moreover,the insult elevated gastric mucosal lipid peroxides(13±0.5 nmol/g tissue,P=0.001),tumor necrosis factor-α(3008.6±78.18 pg/g tissue,P<0.001),prostaglandin E2(117.1 ±4.31 pg/g tissue,P=0.002),and caspase-3 activity (2.4±0.14 OD/mg protein,P=0.002).Conversely,CMS mitigated interleukin-10(627.9±12.82 pg/g tissue,P= 0.001).Furthermore,in animals exposed to CMS,octreotide restored plasma corticosterone(61%and 71%from CMS,P=0.002)at both dose levels.These beneficial effects were associated with a remarkable suppression of gastric lesions(38%and 9%from CMS,P=0.01)and reversal of derangements in gastric mucosa. CONCLUSION:The current investigation provides evidence that exposure to CMS induces gastric ulceration, which was alleviated by administration of octreotide possibly possessing antioxidant,anti-inflammatory,and anti-apoptotic actions. | Noha N Nassar Mona F Schaalan Hala F Zaki Dalaal M Abdallah | 2011 | World Journal of Gastroenterology2011，17，9： | 6 |
| 2 | ABO incompatibility in renal transplantation显示文摘ABO blood group incompatibility(ABO-I)was historically considered an absolute contraindication to kidney transplantation due to the significant risk of acute antibody-mediated rejection and early graft loss.Nevertheless,the urge to minimize the gap between the candidates’number on the waitlist for kidney transplants and the available kidney donors encourage investigation into finding ways to use organs from ABO-I kidney donors,especially in the era of using more potent immunosuppression therapies.This review aims to discuss a general overview of ABO-I kidney transplantation and the different protocols adopted by some transplant centers to meaningfully overcome this barrier. | Mahmoud Mohamed Tara Sweeney Duaa Alkhader Mahmoud Nassar Ahmed Alqassieh Sofia Lakhdar Nso Nso Tibor Fulop Ahmed Daoud Karim M Soliman | 2021 | World Journal of Transplantation2021，11，9： | 2 |
| 3 | Biological control of Sclerotinia minor using achitino|ytic bacteriumand actinomycetes显示文摘 | E1-Tarabily K Soliman M H Nassar A H | 2000 | Plant Pathology2000，49，： | 1 |
| 4 | Unsaturated polyester resins based on rosin maleic anhydride adduct as corrosion protections of steel 显示文摘 | ATI'A A M NASSAR I F BEDAWY H M | 2007 | Reactive & Functional Polymers2007，67，7： | 1 |
| 5 | Studies on estimation of phenotypie stability: Tests of significance for nonparametrie measures of phenotypic stability 显示文摘 | Nassar B Huhn M | 1987 | Biometrics1987，43，： | 1 |
| 6 | Outcome of anaemic monochorionic single survivors following early intrauterine res- cuetransfusion in cases of feto-fetal transfusion syndrome 显示文摘 | Quarello E Stirnemann J Nassar M | 2008 | B JOG2008，115，5： | 1 |
| 7 | Deltamethrin-induced testicular apoptosis in rats:The protective effect of nitric oxide synthese inhibitor显示文摘 | EIGOHARY M AWARA W M NASSAR S | 1991 | Toxicology1991，132，： | 1 |
| 8 | Comparative cost of colour removal from textile effluents using natural adsorbents显示文摘 | NASSAR M M EL-GEUNDI M S | 1991 | Journal of chemical technology and biotechnology1991，50，2： | 1 |
| 9 | Biological control of Sclerotinia minor using a chitinolytic bacterium and actinomycetes 显示文摘 | E1-Tarabily K A Soliman M H Nassar A H | 2000 | Plant Pathology2000，49，5： | 1 |
| 10 | Thermal behavior of bagasse kraft black liquor显示文摘 | Nassar M M | 2003 | Energy Sources2003，25，8： | 1 |
| 11 | Hydrothermal Synthesis of Cobalt Carbonates Using Different Counter Ions : An Efficient Precursor to Nano-sized Cobalt Oxide ( Co304 ) 显示文摘 | Nassar M Y Ahmed I S | 2011 | Polyhedron2011，30，15： | 1 |
| 12 | Dettamethrininduced testicular apoptosis in rats, the protective effect of nitric oxide synthase inhibitor 显示文摘 | El Gohary M Awara WM Nassar S | 1999 | Toxicalogy1999，132，1： | 1 |
| 13 | Fuzzy- Bayesian Network for Refrigeration Compressor Performance Prediction and Test Time Reduction 显示文摘 | Penz C A Flesch C A Nassar S M | 2012 | Expert Systems with Applications2012，39，4： | 1 |
| 14 | Removal of different basic dyes from aqueous solutions by adsorption on palm-fruit bunch particles显示文摘 | Nassar Mamdouh M | 1997 | Chemical Engineering Journal1997，66，3： | 1 |
| 15 | Developing a complexity measure for project schedules显示文摘 | Nassar K M Hegab M Y | 2006 | Journal of construction engineering and management2006，132，6： | 1 |
| 16 | Intra-particle diffusion of basic red and basic yellow dyes on palm fruit bunch显示文摘 | NASSAR M M | 1999 | Water Science Technol1999，40，7： | 1 |
| 17 | Fimbriae-dependent activation of cell adhesion molecule expression in Porphyromonas gingivalis infected endothelial cells 显示文摘 | Khlgatian M Nassar H Chou HH | 2002 | Infect Immun2002，70，1： | 1 |
| 18 | The novel use of decorin in prevention of the develop- ment of proliferative vitreoretinopathy (PVR) 显示文摘 | Nassar K LuKe J LuKe M Kamal M Abd EI-Nabi E Soliman M | 2011 | Graefes Arch Clin Exp Ophthalmol2011，249，11： | 1 |
| 19 | Chromosome doubling induces apomixis in acassava x Manihot anomala hybrid 显示文摘 | Nassar N M A | 2006 | Hereditas2006，143，： | 1 |
| 20 | Production of triploid cassava,Manihot esculenta Crantz by hybrid diploid gametes显示文摘 | Nassar N M A | 1992 | Field Crops Research1992，30，12： | 1 |
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