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1Lamivudine resistance mutations in patients infected with hepatitis B virus genotype D显示文摘AIM: To determine the distribution of viral genotypes for primary or acquired lamivudine resistance. METHODS: A total of 283 patients with chronic hepatitis B virus (HBV) infection (245 patients with chronic hepatitis B and 38 inactive hepatitis B surface antigen carriers) were included in the study. The HBV geno-type was determined by using quantitative real-time polymerase chain reaction and sequence analysis, and tyrosine-methionine-aspartate-aspartate (YMDD) motif mutations were determined using the reverse transcriptase hybridization method. RESULTS: Lamivudine resistance was determined in a total of 25 (10.7%) chronic hepatitis B patients. Eight subjects (4%) had primary resistance to lamivudine, and 17 (53.1%) had secondary resistance to lamivudine. Genotype D, which was isolated from 267 of the patients with chronic HBV infection, was the dominant genotype in Turkey. CONCLUSION: Identification of YMDD motif mutations should have a positive impact on the selection of proper antiviral medication for patients, even for those who are nucleoside nave.Orhan Yιldιz Bilgehan Aygen Nese Demirtürk Tuna Demirdal Dilara Inan Taner Yιldιrmak Arzu Kantürk Ediz Tütüncü Hepatitis B Study Group 2011World Journal of Gastroenterology2011,17,45:3
2Serum unconjugated bile acids as a test for intestinal bacterial overgrowth in dogs显示文摘Melgarejo T Williams DA O' Connell NC 2000Dig Dis Sci2000,45,2:1
3Diabetes nurse educators' prioritized eider foot care behaviors 显示文摘Martinez NC Tripp - Reimer T 2005Diabetes Educ2005,31,6:1
4A systematic review and meta -analysis of the use of oral zinc in the treatment of hepatic encephalopathy显示文摘CHAVEZ-TAPIA NC CESAR -ARCE A BARRIENTOS -GUTI- ERREZ T 2013Nutr J2013,1274,:1
5Epridural morphine improve pain relief and maincains sensory analgesia during continuous epidural bupivacaine after badominal surgery显示文摘Hjortso NC Lund C Mogensen T 1986Anesth Analg1986,65,:1
6Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint 显示文摘Fukushima T Zapata JM Singha NC 2006Immunity2006,24,1:1
7Ganglioneuroma mimicking ovarian tumor: a report of a case and review of the ganglioneuromas显示文摘Murat Gültekin Polat Dursun Coskun Salman ?zgür ?zyüncü Arzu Saglam Türkan Kü?ükali Ali Ayhan 2005Archives of Gynecology and Obstetrics2005,,1:1
8Epidural morphine improves pain relief and maincains sensory analgesia during continuous epidural bupivacaine after abdominal surgery显示文摘Hortso NC Mogensen T 1986Anesth Analg1986,65,:1
9A statistical analysis of factors predisposing patients to heparin resistance显示文摘Chan T Hwang NC Lim CH 2006Perfusion2006,21,2:1
10Regulation of Histone Acetylation in the Nucleus by Sphingo- sine - 1 - Phosphate 显示文摘Hair NC Allegood J Maceyka M Strub GM Harikumar KB Singh SK Luo C Marmorstein R Kordula T Mistien S Spiegel S 2009Science2009,325,5945:1
11Relationship Specialization amongst Sources and Receivers of Social Support and Its Correlations with Loneliness and Subjective Well-Being: A Cross Sectional Study of Nepalese Older 显示文摘Horn NC Tami S Miyako T Ichiro K 2007Archives of Gerontology and Geriatrics2007,,44:1
12Meta - analysis:antibiotic prophylaxis for cir- rhotic patients with upper gastrointestinal bleeding--an updated Cochrane review显示文摘Chavez - Tapia NC Barrientos - Gutierrez T Tellez - Avi- la F 2011Aliment Pharmacol Therapeu- tics2011,34,5:1
13Live three-dimensional transthoracicechocardiographic assessment of aortic dissection显示文摘Htay T Nanda NC Agrawal G 2003Echocardiogr2003,20,:1
14A reduced space interior point strategy for optimization of differential algebraic systems显示文摘Cervantes A.M W(a)chter A Tütüncü R Biegler L.T 0,,01:1
15Consequences of low neonatal iron status due to maternal diabetes mellitus on explicit memo W performance in childhood显示文摘Riggins T Miller NC Bauer PJ 2009Dev Neuropsychol2009,34,6:1
16EDTA: a promoter of proliferation in human corneal endothelium显示文摘Senoo T Obara Y Joyce NC 2000Invest Ophthalmol Vis Sci2000,41,10:1
17显示文摘Abuchowski A Van Es T Palczuk NC 1977J Biol Chem1977,252,:1
18Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter显示文摘Plosch T Kruit JK Bloks VW Huijkman NC Havinga R Duchateau GS Lin Y Kuipers F 0,,08:1
19DNA repair,mitochondria, and neurodegeneration显示文摘Weissman L de Souza Pinto NC Stevnsner T 2007Neuroscience2007,145,4:1
20Provocation of delayedonset muscle soreness in the human jaw-closing muscles显示文摘Türker KS Koutris M Sümer NC 2010Arch Oral Biol2010,55,9:1
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