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| 1 | Mapping of Fertility Restoring Gene for Aegilops kotschyi Cytoplasmic Male Sterility in Wheat Using SSR Markers显示文摘LK783 was found to be a good fertility restorer for K-type male sterility of wheat. Microsatellite markers were employed to map the major restoring gene in LK783. Maintainer and restorer DNA pools were established using the extreme sterile and fertile plants among (KJ5418A//911289/LK783)F1 population,respectively. Seventy-nine sets of SSR primers were screened for polymorphism between the two pools, 6 of which were found polymorphic. Linkage analysis showed that Xgwm11, Xgwm18 , Xgwm264a and Xgwm273were linked to the restoring gene in LK783, while Xgwm11, Xgwm18 and Xgwm273 were co-segregated. The distance between the Rf gene in LK783 and the three co-segregated markers was 6.54±4.37 cM, the distance between Rf gene and Xgwm264a was 5.71±4.10 cM. The four SSR markers were located on chromosome 1BS by amplifying the DNA of nulli-tetrasomics and ditelosomics of CS with the 4 sets of primers, indicating that the major restoring gene in LK783 was located on 1BS, but the relative location of the gene was different from Rfv1, allelism of the two genes should be further investigated. The breeding for new fertility restorer lines of K-type cytoplasmic male sterility in wheat would be facilitated by using the four polymorphic markers. | LIU Bao-shen, SUN Qi-xin, GAO Qing-rong, SUN Lan-zhen, XIE Chao-jie, LI Chuan-you, NI Zhong-fu and DOU Bing-de( Agronomy Department, Shandong Agricultural University, Taian 271018, P.R.China Department of Plant Genetics and Breeding, China Agricultural University, Beijing 100094 , P. R . China ) | 2002 | Agricultural Sciences in China2002，1，8： | 13 |
| 2 | 限制卡路里摄入可抑制大鼠促进动脉衰老的炎症反应,保持年轻的表型显示文摘老化呈指数性增加典型心血管病的发病率和死亡率,这主要是由于动脉壁内分子、细胞和组织水平的动脉促炎变化。动物实验中,大鼠的卡路里限制(calorie restriction,CR)改善了动脉功能并延长了健康跨度和寿命。然而,CR如何影响大鼠动脉壁内分子,细胞和组织表型促炎变化仍有待阐明。该文选取随意喂食的344只年轻(6个月大)和老(24个月大)的Fischer大鼠,获取主动脉;另外选取1组在1个月大时开始只维持40%CR。 | 刘青 叶鹏 Wang MY Zhang L Zhu WQ Zhang J Kim SH Wang YS Ni L Telljohann R Monticone RE McGraw K Liu LJ Rafael de Cabo Lakatta EG | 2018 | 中华高血压杂志2018，26，11： | 3 |
| 3 | Point-of-care testing in the diagnosis of gastrointestinal cancers: Current technology and future directions显示文摘Point-of-care(POC) tests enable rapid results and are well established in medical practice.Recent advances in analytical techniques have led to a new generation of POC devices that will alter gastrointestinal diagnostic pathways.This review aims to identify current and newtechnologies for the POC diagnosis of gastrointestinal cancer.A structured search of the Embase and Medline databases was performed.Papers reporting diagnostic tests for gastrointestinal cancer available as a POC device or containing a description of feasibility for POC application were included.Studies recovered were heterogeneous and therefore results are presented as a narrative review.Six diagnostic methods were identified(fecal occult blood, fecal proteins, volatile organic compounds, pyruvate kinase isoenzyme type M2, tumour markers and DNA analysis).Fecal occult blood testing has a reported sensitivity of 66%-85% and specificity greater than 95%.The others are at a range of development and clinical application.POC devices have a proven role in the diagnosis of gastrointestinal cancer.Barriers to their implementation exist and the transition from experimental to clinical medicine is currently slow.New technologies demonstrate potential to provide accurate POC tests and an ability to diagnose gastrointestinal cancer at an early stage with improved clinical outcome and survival. | Jeremy R Huddy Melody Z Ni Sheraz R Markar George B Hanna | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 4 | Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice显示文摘The mammalian epididymis not only plays a fun dame ntal role in the maturati on of spermatozoa,but also provides protecti on agai nst various stressors.The foremost among these is the threat posed by oxidative stress,which arises from an imbalance in reactive oxygen species and can elicit damage to cellular lipids,proteins,and nucleic acids.In mice,the risk of oxidative damage to spermatozoa is mitigated through the expression and secretion of glutathione peroxidase 5(GPX5)as a major luminal scavenger in the proximal caput epididymidal segment.Accordingly,the loss of GPX5^-/-mediated protection leads to impaired DNA integrity in the spermatozoa of aged Gpx57 mice.To explore the underlying mechanism,we have conducted transcriptomic analysis of caput epididymidal epithelial cells from aged(13 months old)Gpx5^-/-m mice.This analysis revealed the dysregulation of several thousand epididymal mRNA transcripts,in eluding the downregulation of a subgroup of piRNA pathway gen es,in aged Gpx5^-/-mice.In agreeme nt with these fin dings,we also observed the loss of piRNAs,which potentially bind to the P-element-induced wimpy testis(PlWI)-like proteins PIWIL1 and PIWIL2.The absence of these piRNAs was correlated with the elevated mRNA levels of their putative gene targets in the caput epididymidis of Gpx5^-/-mice.Importantly,the oxidative stress response genes tend to have more targeting piRNAs,and many of them were among the top increased genes upon the loss of GPX5^-/-.Taken together,our findings suggest the existence of a previously uncharacterized somatic piRNA pathway in the mammalian epididymis and its possible invoIvement in the aging and oxidative stress-mediated responses. | Chen Chu Lu Yu Joelle Henry-Berger Yan-Fei Ru Ayhan Kocer Alexandre Champroux Zhi-Tong Li Miao He Sheng-Song Xie Wu-Bin Ma Min-Jie Ni Zi-Mei Ni Yun-Li Guo Zhao-Liang Fei Lan-Tao Gou Qiang Liu Samanta Sharma Yu Zhou Mo-Fang Liu Charlie Degui Chen Andrew L Eamens Brett Nixon Yu-Chuan Zhou Joel R Drevet Yong-Lian Zhang | 2020 | Asian Journal of Andrology2020，22，6： | 2 |
| 5 | Changes in the firing pattern of globus pallidus neurons after the degenera- tion of nigrostriatal pathway are mediated by the subthalamic nucleus in the rat显示文摘 | NI Z BOUALI-BENAZZOUZ R GAO D | 2000 | European Journal of Neuroscience2000，12，12： | 1 |
| 6 | Baculovirus- based vaccination vectors allow for efficient induction of immune responses against Plasmodium falcipa- rum circumsporozoite protein显示文摘 | STRAUSS R HUSER A NI S | 2007 | Mol Ther2007，15，： | 1 |
| 7 | Determination of tertiary butylhydroquinone in edible vegetable oils by liquid chromatography/ion trap mass spectrometry显示文摘 | Hao P P Ni J R Sun W L | 2007 | Food Chemistry2007，105，4： | 1 |
| 8 | Age-related de- clines in car following performance under simulated fog conditions显示文摘 | Ni R Kang J J Andersen G J | 2010 | Accident Analysis and Preven- tion2010，42，3： | 1 |
| 9 | An experimental investigation of turbulent thermal convection in water-based Alumina nanofluid显示文摘 | Ni R Zhou S Q Xia K Q | | 0，，： | 1 |
| 10 | Determinants and Economic Consequences of Nonfinancial Disclosure Quality显示文摘 | Dong Y Fu R Gao F Ni C | 2015 | European Ac-counting Review2015，，： | 1 |
| 11 | Preparation and characterization of NaSm9(SiO4)6O2 powders with infrared absorptive properties显示文摘 | ZHANG W Y LU C H NI Y R | 2011 | Materials Letters2011，65，11： | 1 |
| 12 | Immunoassay readout meth- od using extrinsic Raman labels adsorbed on immunogold colloids 显示文摘 | Ni J Lipert R J Dawson GB | 1999 | Anal Chem1999，71，21： | 1 |
| 13 | In Situ and Satellite Observations of a Harmful Algal Bloom and Water Condition at the Pearl River Estuary in Late Autumn 1998显示文摘 | TANG D L KESTER D R NI IH | 2003 | Harmful Algae2003，2，： | 1 |
| 14 | Appropriate BMI levels for PCOS patients in Southern China显示文摘 | Chen X Ni R Mo Y | 2010 | Hum Reprod2010，25，5： | 1 |
| 15 | Thermal conductviities of some organic solvents and their binary mixtures显示文摘 | LEI Q LIN R NI D | 1997 | J Chem Eng Data1997，42，5： | 1 |
| 16 | Upwelling in the Taiwan Strait during the summer monsoon detected by satellite and shipboard measurements 显示文摘 | Tang DanLing Dana R K Ni I- Hsun | 2002 | Remote Sensing of Environment2002，83，： | 1 |
| 17 | Stomatal and nonstomatal limitations to net photosynthesis in seedlings of woody angiosperms显示文摘 | Ni B R Pallardy S G | 1992 | Plant Physical1992，99，15： | 1 |
| 18 | Comparative study on the bioleaching of zinc sulphidos 显示文摘 | SHI S Y FANG Z H NI J R | 2006 | Process Biochemistry2006，41，： | 1 |
| 19 | Simultaneous Processes of Electricity Generation and P-Nitrophenol Degradation in a Microbial Fuel Cell 显示文摘 | ZHU X P NI J R | 2009 | Electrochemistry Communications2009，11，2： | 1 |
| 20 | Preparation and characterization of Sm2O3/Cu mosaic structure with infrared absorptive properties and low infrared emissivity显示文摘 | ZHANG W Y LU C H NI Y R | 2012 | Materials Letters2012，87，： | 1 |
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