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| 1 | Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome显示文摘BackgroundThere 是在质子泵禁止者(PPI ) 和 clopidogrel 之间的可能的不利相互作用上的大争论。另外, PPI 的使用是否少些影响 ticagrelor 遗体的临床的功效,知道。在经皮的冠的干预(一种总线标准) .MethodsWe 回顾地从 “ 分析了数据以后,我们试图与急性冠的症候群(交流)在病人在临床的结果上决定 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响;真实 world” ;,国际,在 2003 和 2014 之间的多中心登记( n = 15,401 )并且在1年的合成主要端点上估计了 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响(所有原因死亡收到 PPI 的病人更老,更经常女性,并且是更可能的有 comorbidities。没有协会为收到 clopidogrel 的病人在 PPI 使用和主要端点之间被观察(调整 HR:1.036;95% CI:0.903-1.189 ) 或 ticagrelor (调整 HR:2.320;95% CI:0.875-6.151 )(P 相互作用 = 0.2004 ) 。同样, PPI 的使用没与所有原因死亡,重新梗塞,或与交流后面的一种总线标准的为与任何一个 clopidogrel 对待的病人或 ticagrelor.ConclusionsIn 病人的严重流血的减少的风险的增加的风险被联系, PPI 的伴随物使用没在收到 clopidogrel 或 ticagrelor 的病人与不利结果的增加的风险被联系。我们的调查结果显示与 clopidogrel 或 ticagrelor 在联合使用 PPI 是合理的,特别在有胃肠的流血的更高的风险的病人。 | Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzfilez-Juanatey Stephen B Wilton Wouter J Kikkert Ivlin Nufiez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiril Sasko Kedev | 2016 | Journal of Geriatric Cardiology2016，13，3： | 12 |
| 2 | DYNAMIC BEHAVIOR ANALYSIS FOR LANDING-GEAR WITH DIFFERENT TYPES OF DUAL-CHAMBER SHOCK-STRUTS显示文摘In this paper three types of dual- chamber shock- struts are considered in dynamic analyses of landing-gear behavior during impact and taxi. Their dynamic characteristics are compared with each other according to calculation results, and some conclusions are presented.It is very helpful for selecting a suitable type of dual-chamber shock-strut in landing-gear design. | Nie Hong Qiao XinAircraft Engineering Department, Nanjing Aeronautical InstituteNanjing 210016, China Gao Zejun R&D Institute of Chendu Aircraft Corp.Chendu 610041, ChinaZhou Lanqin Landing Gear Manufa ctoryBox 43#, Yangxian, Shaanxi 723313, China | 1991 | Chinese Journal of Aeronautics1991，6，2： | 10 |
| 3 | Impact of triple antithrombotic therapy in patients with acute coronary syndrome undergoing percutaneous coronary intervention in real-world practice显示文摘为在急性冠的症候群(交流) 和经皮的冠的干预(一种总线标准) 以后的口头的 anticoagulation (OAC ) 上的病人的 ObjectiveThe 最佳的 antithrombotic 政体仍然保持辩论。寻求回顾地在真实世界的 setting.MethodsWe 评估 OAC 正 clopidogrel 的功效和安全与或没有阿司匹林的这研究分析了数据从一国际,在 2003 和 2014 之间的多中心登记(n = 15,401 ) 。有在一种总线标准以后的交流和收到的 OAC 的病人被屏蔽。合成主要端点是 1 年的所有原因死亡,重新梗塞,或分析注册了 642 个病人包括的严重 bleeding.ResultsThe 期末考试有 OAC 和 clopidogrel (双治疗) 的 62 个病人(9.7%) ,和有阿司匹林, OAC 和 clopidogrel (三倍的治疗) 的联合的 580 个病人(90.3%) 。三倍的治疗上的病人更经常是女性的并且是更可能的有 comorbidities。关于在与三倍的治疗病人一起的双治疗之间的主要结束点没有重要差别[17.74% 对 17.24% ;unadjusted 危险比率(HR ) :1.035;95% 信心间隔(CI ) :0.556-1.929;调整 HR:1.026;95% CI:0.544-1.937 ] 。然而,重新梗塞率比三倍的治疗病人在双治疗是显著地更高的(14.52% 对 5.34% ;unadjusted HR:2.807;95% CI:1.329-5.928;调整 HR:2.333;95% CI:1.078-5.047 ) 。另外,在所有原因死亡和严重 bleeding.ConclusionsIn 的二政体之间没有差别有交流后面的一种总线标准并且与 OAC 的一个指示的真实病人,三倍的治疗没与双治疗相比与不利结果的增加的率被联系。而且,它减少了重新梗塞冒险并且没增加严重流血的风险。 | Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE SerGio Raooseiras-Roubin Emad Abu-Assi Jose P Simao Henriques: Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzalez-Juanate Stephen B Wilton Wouter J Kikkert Ivan Nunez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Morettil Zenon Huczek Toshiharu Fujii Luis cL Correia Masa-aki Kawashiri Sasko Kedev | 2017 | Journal of Geriatric Cardiology2017，14，11： | 6 |
| 4 | Neonatal vitamin A injection promotes cattle muscle growth and increases oxidative muscle fibers显示文摘Background: Vitamin A and its metabolite,retinoic acid(RA),are important regulators of cell differentiation and organ morphogenesis.Its impact on beef cattle muscle growth remains undefined.Method: Angus steer calves were administrated with 0(control) or 150,000 IU vitamin A(retinyl palmitate in glycerol,i.m.) per calf at birth and 1 month of age.At 2 months of age,a biopsy of the Biceps femoris muscle was obtained to analyze the immediate effects of vitamin A injection on myogenic capacity of muscle cells.The resulting steers were harvested at 14 months of age.Results: Vitamin A administration increased cattle growth at 2 months.At 2 months of age,Vitamin A increased PAX7 positive satellite cells and the expression of myogenic marker genes including PAX7,MYF5,MYOD and MYOG.Muscle derived mononuclear cells were further isolated and induced myogenesis in vitro.More myotubes and a higher degree of myogenesis was observed in vitamin A groups.Consistently,vitamin A increased Latissimus dorsi(LD) muscle fiber size at harvest.In addition,vitamin A increased the ratio of oxidative type I and type IIA fibers and reduced the glycolic type IIX fibers.Furthermore,we found that RA,a key bioactive metabolite of vitamin A,activated PPARGC1 A promoter,which explains the upregulated expression of PPARGC1 A in skeletal muscle.Conclusion: Vitamin A administration to neonatal calves enhanced postnatal muscle growth by promoting myogenesis and increasing satellite cell density,accompanied with a shift to oxidative muscle fibers. | Bo Wang Wei Nie Xing Fu Jeanene M de Avila Yannan Ma Mei-Jun Zhu Martin Maquivar Steven M Parish Jan R Busboom Mark L Nelson Min Du | 2019 | Journal of Animal Science and Biotechnology2019，10，1： | 3 |
| 5 | Newly self-administered two-step tool for screening cognitive function in an ageing Chinese population:an exploratory cross-sectional study显示文摘Background Early screening of cognitive function is critical to dementia treatment and care.However,traditional tests require face-to-face administration and are often limited by implementation costs and biases.Aims This study aimed to assess whether the Thoven Cognitive Self-Assessment(TCSA),a novel,innovative two-step touchscreen-based cognition assessment tool,could identify early cognitive impairment due to dementia in older adults.Methods The TCSA was administered to 61 healthy controls(HCs),46 participants with mild cognitive impairment(MCI)and 44 participants diagnosed with dementia recruited from Shanghai.Two outcome measures were generated from the TCSA test:the TCSA_(primary task)score and the TCSA_(secondary task)score.Results The total average scores in the control group for the TCSA_(primary task)and TCSA_(secondary task)were significantly higher than those in the MCI and dementia groups(TCSA_(primary task):HCs vs MCI group vs dementia group,8.58±1.76 vs 5.40±2.67 vs 2.74±2.11,F=75.40,p<0.001;TCSA_(secondary task):HCs vs MCI group vs dementia group,23.02±3.31 vs 17.95±4.93 vs 11.93±5.50,F=76.46,p<0.001).Moreover,receiver operating characteristic analysis showed that a score below 7.5 for the TCSA_(primary task)and a score below 22.5 for the TCSA_(secondary task)were indicators of MCI.Conclusions The TCSA appears to be efficacious for the detection of cognitive impairment in older adults.It demonstrates the potential for large-scale cognition screening in community service settings. | Jing Nie Yang Yang Yining Gao Wenwen Jiang Aisikeer Aidina Fei Sun Lucas R Prieto Jie Yu Kang Ju Lisheng Song Xia Li | 2023 | General Psychiatry2023，36，1： | 2 |
| 6 | Nonlinear - Linear buckling of squarely latticed shallow spherical shells 显示文摘 | LIU R H LI D NIE G H | 1991 | Int J Nonlinear Meeh1991，26，5： | 1 |
| 7 | Tribological behavior of a TiSiCN coating tested in air and coolant 显示文摘 | Xu H Nie X Wei R | 2006 | Surf Coat Teehnol2006，201，： | 1 |
| 8 | Annealing behavior of modified 5083 alloy显示文摘 | LIN S P NIE Z R HUANG H | 2010 | Materials and Design2010，31，： | 1 |
| 9 | Query expansion by mining user logs显示文摘 | Cui H Wen J R Nie J Y | 2003 | IEEE Transactions on Knowledge and Data Engineering2003，15，4： | 1 |
| 10 | Probing single molecules and single nanoparticles by surface enhanced raman scattering 显示文摘 | Nie S Emory S R | 1997 | Science1997，275，： | 1 |
| 11 | Annealing behavior of modified 5083 alloy显示文摘 | Lin S P Nie Z R Huang H | 2010 | Materials and Design2010，31，03： | 1 |
| 12 | Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering显示文摘 | NIE S M EMORY S R | 2002 | Science2002，，275： | 1 |
| 13 | Application and methodology of in vivo K X - ray fluorescence of Pb in bone (impact of KXRF data in the epidemiology of lead toxicity, and consistency of the data generated by updated systems) 显示文摘 | NIE H HU H CHETTLE D R | 2008 | X- Ray Spectrom2008，37，： | 1 |
| 14 | Expression of stimulated by retinoic acid gene 8 ( Stra8 ) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro显示文摘 | Zhou Q Nie R Li Y | 2008 | Biol Reprod2008，79，1： | 1 |
| 15 | Experimental andanalytical study of prestressed steel-concrete compositebeams considering slip effect显示文摘 | Nie J G Cai C S Zhou T R | 2007 | Journal of StructuralEngineering2007，133，4： | 1 |
| 16 | Novel anti-Prelog stereospecific carbony! reductases from Candida parapsilosis for asymmetric reduction of prochiral ketones 显示文摘 | Nie Y Xiao R Xu Y | 2011 | Org Biomol Chem2011，9，11： | 1 |
| 17 | Thermal behav- iour and mechanical properties of novel RTV silicone rubbers using divinyl-hexa - POSS as cross-linker显示文摘 | CHEN D Z NIE J R YI S P | 2010 | Polym Degrad Stab2010，95，4： | 1 |
| 18 | Absorption enhancement of fractal frequency selective surface absorbers by using microwave absorbing material based substrates显示文摘 | LIAO Z Q GONG R Z NIE Y | | 0，，03： | 1 |
| 19 | Polymorphisms in immtme/inflammatory cytokine genes are related to Parkinson' s disease withcognitive impairment in the Han Chinese population显示文摘 | Nie K Zhang Y Can R | 2013 | Neurosei Lett2013，541，： | 1 |
| 20 | Saponins from Bolbostemma paniculatum: cycFac bisdesmosides, tubeimosides II and III 显示文摘 | Kasai R Miyakoshi M Nie R L | 1988 | Phytochemistry1988，27，5： | 1 |
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