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| 1 | Helicobacter pylori in dental plaque and stomach of patients from Northern Brazil显示文摘AIM: To establish whether virulence factor genes vacA and cagA are present in Helicobacter pylori (H. pylori) retrieved from gastric mucosa and dental plaque in pa-tients with dyspepsia. METHODS: Cumulative dental plaque specimens and gastric biopsies were submitted to histological exami-nation, rapid urease test and polymerase chain reac-tion (PCR) assays to detect the presence of cagA and vacA polymorphisms.RESULTS: Detection of H. pylori from dental plaque and gastric biopsy samples was greater by PCR com-pared to histological examination and the rapid ure-ase test. DNA from H. pylori was detected in 96% of gastric mucosa samples and in 72% of dental plaque samples. Sixty-three (89%) of 71 dental plaque sam-ples that were H. pylori-positive also exhibited identical vacA and cagA genotypes in gastric mucosa. The most common genotype was vacAs1bm1 and cagA positive, either in dental plaque or gastric mucosa. These viru-lent H. pylori isolates were involved in the severity of clinical outcome.CONCLUSION: These pathogenic strains were found simultaneously in dental plaque and gastric mucosa, which suggests that gastric infection is correlated with the presence of H. pylori in the mouth. | Mnica Baraúna Assumpo Luisa Caricio Martins Hivana Patricia Melo Barbosa Katarine Antonia dos Santos Barile Sintia Silva de Almeida Paulo Pimentel Assumpo Tereza Cristina de Oliveira Corvelo | 2010 | World Journal of Gastroenterology2010，16，24： | 29 |
| 2 | Interleukin-1 and TNF-α polymorphisms and Helicobacter pylori in a Brazilian Amazon population显示文摘AIM:To study the association between Interleukin-1(IL-1)and tumor necrosis factor(TNF)-αpolymorphisms,infection by Helicobacter pylori(H pylori)and the development of gastrointestinal diseases.METHODS:Genomic DNA was extracted from the peripheral blood of 177 patients with various gastrointestinal diseases and from 100 healthy volunteers.The polymorphisms in IL-1βand TNF-αgenes were analyzed using the polymerase chain reactionrestriction fragment length polymorphism method(PCRRFLP)and those from IL-1RN with PCR.The presence of infection due to H pylori and the presence of the CagA toxin were detected by serology.The histopathological parameters in the gastric biopsies of the patients were according to the Sydney classification.RESULTS:A comparison of the frequencies of the different polymorphisms studied among the patients and the control group demonstrated that the allele IL1RN*2 was more frequent among patients with gastric ulcers and adenocarcinoma.Carriers of the allele ILRN*2 and those with reactive serology for anti-CagA IgG had a greater risk of developing peptic ulcer and gastric adenocarcinoma,as well as a higher degree of inflammation and neutrophilic activity in the gastric mucosa.CONCLUSION:Our results indicate a positive association between IL-1RN gene polymorphism and infection by positive H pylori CagA strains and the development of gastric ulcers and adenocarcinoma. | Hivana Patricia Melo Barbosa Luisa Caricio Martins Sidney Emanuel Batista dos Santos Samia Demachki Mnica Baraúna Assumpo Charliana Damasceno Arago Tereza Cristina de Oliveira Corvelo | 2009 | World Journal of Gastroenterology2009，15，12： | 17 |
| 3 | 骨折相关性感染定义的共识显示文摘骨折相关性感染(fracture related infection,FRI)是创伤骨科一种常见的严重并发症.迄今为止,尚无明确定义,因此很难对该并发症带来的影响进行准确评估和对现有的研究展开比较.为解决这一难题,在AO基金会的支持下,我们成立了一个由科学家和医学专家组成的专家组,旨在对FRI定义达成的共识. | Metsemakers WJ Morgenstern M McNally MA Moriarty TF McFadyen I Scarborough M Athanasou NA Ochsner PE Kuehl R Raschke M Borens O 谢肇 Velkes S Hungerer S Kates SL Zalavras C Giannoudis PV Richard RG Verhofstad MH 喻胜鹏 孙东 汪小华 | 2018 | 中华骨科杂志2018，38，9： | 8 |
| 4 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 5 | Electrochemical Lithium Storage Performance of Molten Salt Derived V_(2)SnC MAX Phase显示文摘MAX phases are gaining attention as precursors of two-dimensional MXenes that are intensively pursued in applications for electrochemical energy storage.Here,we report the preparation of V_(2)SnC MAX phase by the molten salt method.V_(2)SnC is investigated as a lithium storage anode,showing a high gravimetric capacity of 490 mAh g−1 and volumetric capacity of 570 mAh cm^(−3) as well as superior rate performance of 95 mAh g^(−1)(110 mAh cm^(−3))at 50 C,surpassing the ever-reported performance of MAX phase anodes.Sup-ported by operando X-ray diffraction and density functional theory,a charge storage mechanism with dual redox reaction is proposed with a Sn-Li(de)alloying reaction that occurs at the edge sites of V_(2)SnC particles where Sn atoms are exposed to the electrolyte followed by a redox reaction that occurs at V_(2)C layers with Li.This study offers promise of using MAX phases with M-site and A-site elements that are redox active as high-rate lithium storage materials. | Youbing Li Guoliang Ma Hui Shao Peng Xiao Jun Lu Jin Xu Jinrong Hou Ke Chen Xiao Zhang Mian Li Per OÅPersson Lars Hultman Per Eklund Shiyu Du Zhifang Chai Zhengren Huang Na Jin Jiwei Ma Ying Liu Zifeng Lin Qing Huang | 2021 | Nano-Micro Letters2021，13，10： | 2 |
| 6 | Low temperature induced changes in activity and protein levels of the enzymes associated to conversion of starch to sucrose in banana fruit显示文摘 | Roberta Ghedini Der Agopian Fernanda Helena Gon?alves Peroni-Okita Claudinéia Aparecida Soares Janaína Aparecida Mainardi Jo?o Roberto Oliveira do Nascimento Beatriz Rosana Cordenunsi Franco Maria Lajolo Eduardo Purgatto | 2011 | Postharvest Biology and Technology2011，，2： | 2 |
| 7 | 用中子球测量重离子碰撞中单举中子多重性显示文摘本文介绍用中子球探测器测量重离子核反应中的单举中子多重性分布.给出在27、35、44和77MeV/u四个轰击能量下^(40)Ar+^(197)Au,^(40)Ar+^(232)Th两个反应体系的实验结果.单举中子多重性分布反映了在反应过程中不同耗散程度的碰撞的相对贡献. | D.Guerreau 江栋兴 J.Galin H.Doubre J.Pouthas M.Morjean J.Fréchaut J.L.Charvet Y.Patin B.Lott Y.Pranal C.Ma■na■o J.L.Uzureau U.Jahnke G.In■old D.Jacqet | 1990 | 高能物理与核物理1990，14，6： | 2 |
| 8 | Complications and Outcome After Acute Stroke: Does Dysphagia Matter?显示文摘 | D.G. Smithard NA O’Neill C. Park J. Morris R. Wyatt R. England D.F. Martin | 1996 | Stroke A Journal of Cerebral Circulation1996，，7： | 2 |
| 9 | Simvastain inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels显示文摘 | Turner NA O'Regan DJ Ball SG | 2005 | FASFB J2005，19，7： | 1 |
| 10 | Two distinct cellular mechanisms of osteoclast formation and bone resorption in periprosthetic osteolysis显示文摘 | Sabokbar A Kudo O Athanasou NA | 2003 | J Orthop Res2003，21，1： | 1 |
| 11 | Flexible bronehoseopic management of benign tracheal stenosis: long term follow-up of 115 patients显示文摘 | Rahman NA Fruebter O Shitrit D | 2010 | J Cardiot horac Surg2010，5，： | 1 |
| 12 | Multiplex PCR: critical parameters and step-by-step protocol 显示文摘 | Henegariu O Heerema NA Dlouhy SR | 1997 | Biotechniques1997，23，3： | 1 |
| 13 | Lymphocyte Subsets in Peripheral Blood of Dogs a Flow Cviometric Study显示文摘 | Martin Faldyna Lenka Levá Pavlína Kn(o)tigová | 2001 | Vet Immunol Immunopathol2001，83，： | 1 |
| 14 | Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA显示文摘 | Porter KE Turner NA O'Regan DJ | 2004 | Cardiovasc Res2004，61，4： | 1 |
| 15 | Post-traumatic moderate systemic hypothermia reduces TUNEL positive cells following spinal cord injury in rat显示文摘 | Shibuya S Miyamoto O Janjua NA | 2004 | Spinal Cord2004，42，1： | 1 |
| 16 | Intrapleural heparin or heparin combined with human recombinant DNase is not effective in the treatment of emphysema in a rabbit model显示文摘 | Dikensoy O Zhu Z Na MJ etc | 2006 | Respirology2006，11，： | 1 |
| 17 | Diagnostic value of pleural fluid N-termlnal pro-brain natriuretic peptide lev- els in patients with cardiovascular diseases 显示文摘 | Liao H Na M J Dikensoy O | 2008 | Respirolo- gy2008，13，1： | 1 |
| 18 | Glucose variability and mortality in patients with sepsis显示文摘 | Ali NA O'Brien JJ D ungan K | 2008 | Crit Care Med2008，36，： | 1 |
| 19 | Lymphomas with concurrent BCL2 and MYC translocations:The critical factors associated with survival显示文摘 | Johnson NA Savage K J Ludkovski O | | 0，，11： | 1 |
| 20 | Multiplex PCR: Critical Parameters and Step-by-Step Protocol显示文摘 | Henegariu O Heerema NA Dlouhy SR | 1997 | Bio Techniques1997，23，3： | 1 |
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