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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 3 | On prediction of crack in different orientations in pipe using frequency based approach显示文摘 | Naniwadekar M R Naik S S Maiti S K | 2008 | Mechanical Systems and Signal Processing2008，22，3： | 1 |
| 4 | Separation of oildispersions from water by fibrous bed coalescence 显示文摘 | LANGDON W M NAIK P P WASAN D T | 1972 | Environ SciTeeh1972，6，10： | 1 |
| 5 | Jasmonic acid induced changes in protein pattern, antioxidative enzyme activities and peroxidase isoenzymes in peanut seedlings显示文摘 | Kumari G J Reddy A M Naik S T | 2006 | Biologia Plantarum2006，，50： | 1 |
| 6 | Water transporta- tion through organic coatings: Correlation between electro- chemical impedance measurements, gravimetry, and water vapor permeability显示文摘 | Shreepathi S Naik S M Vattipalli M R | 2012 | Journal of Coatings Technology and Research2012，9，4： | 1 |
| 7 | Thermochemotherapy in hereditary retinoblatoma 显示文摘 | Murthy R Honayar SG Naik M | 2003 | Br J Ophthalmol2003，87，10： | 1 |
| 8 | Review of composting and anaerobic digestion of municipal solid waste and a methodological proposal for a mid-size city 显示文摘 | Silva M R Q Naik T R | 2007 | Sustainable Construction Materials and Technologies2007，，： | 1 |
| 9 | P-glycoprotein expression in multidrug-resistant human ovarian carcinoma cell lines显示文摘 | Bradley G Naik M Ling V | 1989 | Cancer Res1989，49，10： | 1 |
| 10 | Speaker verification:Atutorial显示文摘 | Naik J M | 1990 | IEEE Commutation Magazine1990，28，1： | 1 |
| 11 | Severe sequence-specific toxicity when capecitabine is given after Fluorouracil and leucovorin显示文摘 | HENNIG I M NAIK J D BROWN S | 2008 | J Clin Oncol2008，26，20： | 1 |
| 12 | Production of biodiesel from high free fatty acid karanja (pongamia pinnata) oil显示文摘 | Naik M Meher L C Naik S N | 2008 | Biomass & Bioenergy2008，32，4： | 1 |
| 13 | Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance显示文摘 | Mukanganyama S Widersten M Naik YS | 2002 | Int J Cancer2002，97，5： | 1 |
| 14 | A secondorder autocorrelator for single-shot measurement of femtosecond laser pulse durations 显示文摘 | M raghuramaiah A K sharma P A naik | 2001 | Sadhana2001，26，6： | 1 |
| 15 | Blind adaptive recognition of different QPSK modulation signals for software defined radio application显示文摘 | Naik M V Bhattacharjee R Mahanta A | 2006 | IEEE COMSWARE2006，5，01： | 1 |
| 16 | Efficient simulation of time-dependent flows: application to a twin screw extruder显示文摘 | Janhavi S Raut Vijay M Naik | 2003 | AICHE Journal2003，49，8： | 1 |
| 17 | Metal ion binding properties of novel wool powders显示文摘 | RADHIKA Naik GUIQING Wen DHARMAPRAKASH M S | 2010 | Journal of Applied Polymer Science2010，115，： | 1 |
| 18 | Enzymatic glycerolysis for conversion of sunflower oil to food based emulsifiers显示文摘 | Naik M K Naik S N Mohanty S | 2014 | Catalysis Today2014，237，6： | 1 |
| 19 | On predection of crack in different orientations in pipe using frequency based approach 显示文摘 | Naniwadekar M R Naik S S Maiti S K | 2008 | Mechanical Systems and Signal Processing2008，22，3： | 1 |
| 20 | Thermoche- mothempy in hereditary retinoblastorna 显示文摘 | MURTHY R HONAVAR S G NAIK M | 2003 | British Journal ofOphthalmology2003，87，11： | 1 |
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