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| 1 | Towards a global One Health index: a potential assessment tool for One Health performance显示文摘Background:A One Health approach has been increasingly mainstreamed by the international community, as it provides for holistic thinking in recognizing the close links and inter-dependence of the health of humans, animals and the environment. However, the dearth of real-world evidence has hampered application of a One Health approach in shaping policies and practice. This study proposes the development of a potential evaluation tool for One Health performance, in order to contribute to the scientific measurement of One Health approach and the identification of gaps where One Health capacity building is most urgently needed.Methods:We describe five steps towards a global One Health index (GOHI), including (i) framework formulation;(ii) indicator selection;(iii) database building;(iv) weight determination;and (v) GOHI scores calculation. A cell-like framework for GOHI is proposed, which comprises an external drivers index (EDI), an intrinsic drivers index (IDI) and a core drivers index (CDI). We construct the indicator scheme for GOHI based on this framework after multiple rounds of panel discussions with our expert advisory committee. A fuzzy analytical hierarchy process is adopted to determine the weights for each of the indicators.Results:The weighted indicator scheme of GOHI comprises three first-level indicators, 13 second-level indicators, and 57 third-level indicators. According to the pilot analysis based on the data from more than 200 countries/territories the GOHI scores overall are far from ideal (the highest score of 65.0 out of a maximum score of 100), and we found considerable variations among different countries/territories (31.8–65.0). The results from the pilot analysis are consistent with the results from a literature review, which suggests that a GOHI as a potential tool for the assessment of One Health performance might be feasible.Conclusions:GOHI—subject to rigorous validation—would represent the world’s first evaluation tool that constructs the conceptual framework from a holistic perspective of One Health. Future application of GOHI might promote a common understanding of a strong One Health approach and provide reference for promoting effective measures to strengthen One Health capacity building. With further adaptations under various scenarios, GOHI, along with its technical protocols and databases, will be updated regularly to address current technical limitations, and capture new knowledge. | Xiao-Xi Zhang Jing-Shu Liu Le-Fei Han Shang Xia Shi-Zhu Li Odel YLi Kokouvi Kassegne Min Li Kun Yin Qin-Qin Hu Le-Shan Xiu Yong-Zhang Zhu Liang-Yu Huang Xiang-Cheng Wang Yi Zhang Han-Qing Zhao Jing-Xian Yin Tian-Ge Jiang Qin Li Si-Wei Fei Si-Yu Gu Fu-Min Chen Nan Zhou Zi-Le Cheng Yi Xie Hui-Min Li Jin Chen Zhao-Yu Guo Jia-Xin Feng Lin Ai Jing-Bo Xue Qian Ye Liz Grant Jun-Xia Song Geoff Simm Jürg Utzinger Xiao-Kui Guo Xiao-Nong Zhou | 2022 | Infectious Diseases of Poverty2022，11，3： | 3 |
| 2 | The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs. | Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou | 2023 | Horticulture Research2023，10，5： | 3 |
| 3 | 多种代用资料和模型模拟得到的亚洲季风在8.2ka显著气候影响的证据(英文)显示文摘Given the likelihood of future reductions in the strength of the Atlantic Meridional Overturning Circulation(AMOC),it is important to document how changes in the AMOC have altered climate patterns in the past and to assess the skill of coupled climate models in reproducing these teleconnections.Of past abrupt changes in the AMOC,the 8.2 ka event provides a particularly useful case study because its duration,magnitude of AMOC reduction and background climate state are closest to conditions expected in the future.In this research,we present an expanded proxy synthesis of the 8.2 ka event in monsoonal Asia,including new high-resolution lake and bog records,more sites from the East Asia monsoon region and proxies of winter monsoon strength.We compare proxy evidence with a new simulation of the 8.2 ka event using the Community Climate System Model version 3(CCSM3) and prescribing North Atlantic freshwater forcing according to the latest reconstructions.We find clear and objectively-determined evidence for 8.2 ka climate anomalies at nearly all of the fourteen proxy sites,emphasizing the strong and widespread impacts of the event in monsoonal Asia during both summer and winter seasons.The model simulation corroborates that these anomalies,described generally as a weakening of the summer monsoon and strengthening of the winter monsoon,were likely caused by a reduction of the AMOC.Examination of regional anomalies in East Asia reveals some spatial heterogeneity,however,that in the model simulation is caused by contraction of the seasonal migration of the subtropical monsoon front.The duration of climate anomalies at 8.2 ka in monsoonal Asia,both in proxy records and the model simulation,generally matches the duration of the event in Greenland ice core δ^(18)O,further supporting a tight connection to the North Atlantic. | MORRILL Carrie WAGNER Amy J OTTO-BLIESNER Bette L ROSENBLOOM Nan | 2011 | 地球环境学报2011，2，3： | 3 |
| 4 | Chitosan-coated nanoliposome as vitamin E carrier显示文摘 | LIU Nan PARK H J | 2009 | J Microencapsul2009，26，3： | 1 |
| 5 | Volatile composition of Chinese Hippophae rhamnoides and its chemotaxonomic implications 显示文摘 | Tian C J Nan P Chen J K | 2004 | Biochem Syst Ecol2004，32，： | 1 |
| 6 | Some anzahl theorems is vectorspace over Z/p^kZ 显示文摘 | You H Nan J Z | 1996 | Acta Math Scientia1996，1，16： | 1 |
| 7 | Transplantation of a novel cell line population of umbilical cord blood stem cells ameliorates neurological deficits associated with ischemic brain injury显示文摘 | Xiao J Nan Z Motooka Y | 2005 | Stem Cells Dev2005，14，： | 1 |
| 8 | Coronary restenotic reduction of drug-eluting stenting may be due to its anti-inflammatory effects 显示文摘 | Li JJ Li J Nan JL | 2007 | Med Hypotheses2007，69，5： | 1 |
| 9 | Bioinformatics and structural characterization of a hypothetical protein from streptococcus mutans: implication of antibiotic resistance显示文摘 | Nan J Brostromer E Liu X Y | 2009 | PLoS One2009，4，10： | 1 |
| 10 | A new Neotyphodium species symbiotic with drunken horse grass (Achnatherum inbrians)in China 显示文摘 | Li C J Nan Z B Paul V H | 2004 | Myotaxon2004，90，1： | 1 |
| 11 | Oxygen consumption and ammonia-N excretion of Penaeus Chinensis (Osbeck, 1765)juveniles at different salinity levels (Decapoda, Penaeidae)显示文摘 | Chen J C Nan F H | 1995 | Crusta- eeana1995，68，8： | 1 |
| 12 | Effect of PAC addition on immersed uhrafiltration for the treatment of algal-rich water 显示文摘 | Zhang Y Tian J Y Nan J | 2011 | Journal of Hazardous Materials2011，186，23： | 1 |
| 13 | Ishikawa and Mann Iterative Processes with Errors for Set-Valued Strongly Accretive and φ- Hemicontractive Mappings 显示文摘 | Huang Nan Jing Cho Y J Kang S M et ai | 2000 | Math Comput Modelling2000，32，： | 1 |
| 14 | Interactions of Neotyphodium gansuense, Achnatherum inebrians and plant pathogenic fungi 显示文摘 | Li C J Gao J Nan Z B | 2007 | Mycological Research2007，，： | 1 |
| 15 | Scripta Materialia显示文摘 | Nan Z Y Ishihara S McEvily A J | 2007 | 56(8): 6492007，56，8： | 1 |
| 16 | Comparison of the neuroapoptotic properties of equipoteut anesthetic concentrations of desflurane,isoflurane,or sevoflurane in neonatal mice显示文摘 | Istaphanous GK Howard J Nan X | 2011 | Anesthesiology2011，114，3： | 1 |
| 17 | Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 Cells显示文摘 | LI Nan NEU J | 2009 | Journal of Nutrition2009，139，4： | 1 |
| 18 | Synthesis and electrochemical characteristics of an orthorhombic LiMnO2 cathode material modified with poly(vinyl-pyrrolidone) for lithium ion batteries 显示文摘 | LIU C NAN J M ZUO X X | 2012 | Int J Electrochem Sci2012，7，： | 1 |
| 19 | Effect of extract of Ginkgo bi-Ioba on doxombicin-associated cardiotoxicity in patients with breast cancer 显示文摘 | Yi S Y Nan K J Chen S J | 2008 | Zhongguo Zhong Xi Yi Jie He Za Zhi2008，28，1： | 1 |
| 20 | Recyeling spent zinc manganese dioxide batteries through synthesizing Zn-Mn ferrite magnetic mate- rials 显示文摘 | NAN J M HAND M CUI M | 2006 | Journal of Hazardous Materials2006，133，： | 1 |
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