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| 1 | Different profile of cytokine synthesis according to the severity of acute pancreatitis显示文摘AIM: To evaluate the cellular synthetic ability of cytokines involved in pro- and anti-inflammatory reactions in patients with AP.METHODS: Sixty-seven patients with AP (16 severe,51 mild) and 10 controls were included in the study.Cultures of whole blood were performed in samples obtained within the first 72 h from the onset of pain.Serum levels of interleukins (IL) 6, 8, 10, and TNF-α were measured at baseline and in the supernatant of cultures with (functional reserve) or without stimulation with phytohemaglutinin.RESULTS: Basal levels of cytokines were significantly higher in patients with severe AP. A significant increase of all pro-inflammatory cytokines vs basal levels was observed in the supernatant after 24 h of whole blood cultures in patients, but not in controls. In contrast, IL-10 increased significantly in the supernatant of cultures only in patients with mild AP. Cells showed a statistically significant functional reserve for all IL in patients with mild, but only for pro-inflammatory cytokines in patients with severe AP.CONCLUSION: A marked activation of immune system may be observed in patients with AP, being balanced between pro- and anti-inflammatory cytokines in patients with mild but not severe AP. A reduced functional reserve for the synthesis of IL-10 may be observed in patients with severe AP, which might lead to a worst prognosis. | Raquel Laveda Juan Martínez Carlos Mu■oz Juan Carlos Penalva Jesus Sáez Germán Belda Salvador Navarro Faust Feu Anton Mas José Ma Palazón José Sánchez-Payá José Such Miguel Pérez-Mateo | 2005 | World Journal of Gastroenterology2005，11，34： | 24 |
| 2 | 大规模MIMO系统上行链路时间-空间结构信道估计算法显示文摘针对大规模多入多出(MIMO)系统上行链路非平稳空间相关信道的估计问题,该文利用信道的时间-空间2维稀疏结构信息,应用狄利克雷过程(DP)和变分贝叶斯推理(VBI),设计了一种低导频开销和计算复杂度的信道估计迭代算法,提高了信道估计精度。由于平稳空间相关信道难以适用于大规模MIMO系统,该文借助于狄利克雷过程构建了非平稳空间相关信道先验模型,可将具有空间关联的多个物理信道映射为具有相同时延结构的概率信道,并应用变分贝叶斯推理设计了低导频开销和计算复杂度的信道估计迭代算法。实验结果验证了所提算法的有效性,且具有对系统关键参数鲁棒性的优点。 | 路新华 MANCHÓN Carles Navarro 王忠勇 张传宗 | 2020 | 电子与信息学报2020，42，2： | 7 |
| 3 | Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery显示文摘BACKGROUND Liver resection surgery has advanced greatly in recent years,and the adoption of fasttrack programs has yielded good results.Combination anesthesia (general anesthesia associated to epidural analgesia) is an anesthetic-analgesic strategy commonly used for the perioperative management of patients undergoing surgery of this kind,though there is controversy regarding the coagulation alterations it may cause and which can favor the development of spinal hematomas.AIM To study the postoperative course of liver resection surgery,an analysis was made of the outcomes of liver resection surgery due to colorectal cancer metastases in our centre in terms of morbiditymortality and hospital stay according to the anesthetic technique used (general vs combination anesthesia).METHODS A prospective study was made of 61 colorectal cancer patients undergoing surgery due to liver metastases under general and combination anesthesia between January 2014 and October 2015.The patient characteristics,intraoperative variables,postoperative complications,evolution of hemostatic parameters,and stay in intensive care and in hospital were analyzed.RESULTS A total of 61 patients were included in two homogeneous groups: general anesthesia (n = 30) and combination anesthesia (general anesthesia associated to epidural analgesia)(n = 31).All patients had normal coagulation values before surgery.The international normalized ratio (INR) in both the general and combination anesthesia groups reached maximum values at 2448 h (mean 1.37 and 1.45 vs 1.39 and 1.41,respectively),followed by a gradual decrease.There was less intraoperative bleeding in the combination anesthesia group (769 mL) than in the general anesthesia group (1200 mL)(P < 0.05).Of the 61 patients,38.8% in the general anesthesia group experienced some respiratory complication vs 6.6% in the combination anesthesia group (P < 0.001).The time to gastrointestinal tolerance was significantly correlated to the type of anesthesia,though not so the stay in critical care or the time to hospital discharge.CONCLUSION Epidural analgesia in liver resection surgery was seen to be safe,with good results in terms of pain control and respiratory complications,and with no associated increase in complications secondary to altered hemostasis. | Guillermo Perez Navarro Ana Maria Pascual Bellosta Sonia María Ortega Lucea Mario Serradilla Martín Jose Manuel Ramirez Rodriguez Javier Martinez Ubieto | 2019 | World Journal of Clinical Cases2019，7，17： | 4 |
| 4 | Randomized Controlled Trial of Danoprevir Plus Peginterferon Alfa-2a and Ribavirin in Treatment-Naive Patients with HCV Genotype 1 Infection显示文摘 | P. Marcellin C. Cooper L. Balart D. Larrey T. Box E. Yoshida E. Lawitz P. Buggisch P. Ferenci M. Weltman E. Labriola-Tompkins S. Le Pogam I. Nájera D. Thomas G. Hooper N.S. Shulman Y. Zhang M.T. Navarro C.Y. Lim M. Brunda N.A. Terrault E.S. Yetzer | 2013 | Gastroenterology2013，，： | 2 |
| 5 | Estimation of rainfall thresholds for shallow landslides in the Sierra Madre Oriental, northeastern Mexico显示文摘Landslides induced by prolonged rainfalls are frequent mass movements along the northeastern portion of the Sierra Madre Oriental in Mexico,causing significant damage to infrastructure.In this work,we have studied the connection between rainfall and landslides in the Santa Rosa Canyon,a catchment located in the northeastern Mexico.A landslide database triggered by major storms and hurricanes that have hit the region over the past 30 years was analyzed.A total of 92 rainfall events in the Santa Rosa Canyon were studied to determine the amount of precipitation needed to trigger shallow landslides.For each event the duration(D,in hours)and the cumulated rainfall event(E,in mm)were determined by using historical rainfall data from weather stations located near the study area.We have proposed an ED threshold for rainfall-induced landslides with durations 0.5 | Jorge A.Salinas-Jasso Fernando Velasco-Tapia Ignacio Navarro de León Ricardo A.Salinas-Jasso Efraín Alva-Nino | 2020 | Journal of Mountain Science2020，17，7： | 2 |
| 6 | Minimization of methabenzthiazuron residues in leaching water using amended soils and photocatalytic treatment with TiO_2 and ZnO显示文摘In the present work, potential groundwater pollution by methabenzthiazuron(MTBU) and the effect of three different amendments(composted sheep manure, composted pine bark and spent coffee grounds) on its mobility were investigated under laboratory conditions. The efficiency of ZnO and TiO2 suspensions in the photocatalytic degradation of MTBU in leaching water was also investigated. The relative and cumulative breakthrough curves were obtained from disturbed soil columns. The presence and/or addition of organic matter drastically reduced the movement of the herbicide. On other hand, photocatalytic experiments showed that the addition of ZnO and TiO2 strongly enhances the degradation rate of this herbicide compared with the results of photolytic experiments under artificial light. ZnO appeared to be more effective in MTBU oxidation than TiO2. The results obtained point to the interest of using organic wastes and heterogeneous photocatalysis for reducing the pollution of groundwater by pesticide drainage. | Jos Fenoll Pilar Flores Pilar Hellín Joaquín Hern'andez Simón Navarro | 2014 | Journal of Environmental Sciences2014，26，4： | 2 |
| 7 | Improvement of shoot-tip grafting in vitro for virus-free citrus 显示文摘 | Navarro L Roistacher N C Murshige T | 1975 | Amer Soc Hort Sci1975，100，5： | 1 |
| 8 | Molecular characterisation of Cryptosporidium isolates from pet reptiles显示文摘 | Susana Pedraza-Díaz Luis M. Ortega-Mora Beatriz A. Carrión Vanesa Navarro Mercedes Gómez-Bautista | 2008 | Veterinary Parasitology2008，，3： | 1 |
| 9 | Spinal cord injury induces endoplasmic reticulum stress w ith different cell-type dependent response显示文摘 | Penas C Guzmn MS VerdúE Forés J Navarro X Casas C | 2007 | J Neurochem2007，102，4： | 1 |
| 10 | CBN and vitrified bond:A new focus显示文摘 | Navarro N P | 1986 | Machine and tool blue book1986，81，10： | 1 |
| 11 | Application of Matrix Solid-phase Dispersion to the Determination of a New Generation of Fungicides in Fruits and Vegetables显示文摘 | Navarro M Picó Y Marín R | 2002 | Journal of Chromatography A2002，，968： | 1 |
| 12 | UVB effects on early developmental stages of commercially important macroalgae in southern Chile 显示文摘 | Navarro N P Mansilla A Palacios M | 2008 | J Appl Phyco12008，20，： | 1 |
| 13 | Follicular hormonal enrironment and embryo quality in wemen with endometriosis显示文摘 | | 2000 | Hum Reprod Vpdate2000，6，1： | 1 |
| 14 | miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer显示文摘 | Gallardo E Navarro A Vinolas N | 2009 | Carcinogenesis2009，30，11： | 1 |
| 15 | Integrated CMOS amplifier for ENG signal recording 显示文摘 | URANGA A NAVARRO X BARNIOL N | 2004 | IEEE Trans Biomed Engineer2004，51，12： | 1 |
| 16 | Electrical strength in ramp voltage AC tests of LDPE and its nanocomposites with silica and fibrous and laminar silicates显示文摘 | Hoyos M Garcia N Navarro R | 2008 | Journal of Polymer Science Part B-Polymer Physics2008，46，13： | 1 |
| 17 | Modified (NHC) Pd (allyl) Cl ( NHC = N-heterocyclic carbene) complexes for room-temperature Suzuki-Miyaura and Buchwald-Hartwig reactions显示文摘 | Marion N Navarro O Mei J G | 2006 | J Am Chem Soc2006，12，12： | 1 |
| 18 | MicroRNAs Expressed during Lung Cancer Development Are Expressed in Human Pseud?ogiandular Lung Embryogenesis 显示文摘 | Navarro A Marrades RM Vinolas N | 2009 | Oncology2009，76，3： | 1 |
| 19 | Magnetically aligned collagen gel filling a collagen nerve guide improves peripheral nerve regeneration显示文摘 | Ceballos D Navarro X Dubey N | 1999 | Exp Neurol1999，158，2： | 1 |
| 20 | Is ultrasonography a good screening test for intestinal malrotation? 显示文摘 | Orzech N Navarro OM Langer JC | 2006 | J Pediatr Surg2006，41，5： | 1 |
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