|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Rehabilitation of spinal cord injuries显示文摘Spinal cord injury(SCI) is the injury of the spinal cord from the foramen magnum to the cauda equina whichoccurs as a result of compulsion, incision or contusion. The most common causes of SCI in the world are traffic accidents, gunshot injuries, knife injuries, falls and sports injuries. There is a strong relationship between functional status and whether the injury is complete or not complete, as well as the level of the injury. The results of SCI bring not only damage to independence and physical function, but also include many complications from the injury. Neurogenic bladder and bowel, urinary tract infections, pressure ulcers, orthostatic hypotension, fractures, deep vein thrombosis, spasticity, autonomic dysreflexia, pulmonary and cardiovascular problems, and depressive disorders are frequent complications after SCI. SCI leads to serious disability in the patient resulting in the loss of work, which brings psychosocial and economic problems. The treatment and rehabilitation period is long, expensive and exhausting in SCI. Whether complete or incomplete, SCI rehabilitation is a long process that requires patience and motivation of the patient and relatives. Early rehabilitation is important to prevent joint contractures and the loss of muscle strength, conservation of bone density, and to ensure normal functioning of the respiratory and digestive system. An interdisciplinary approach is essential in rehabilitation in SCI, as in the other types of rehabilitation. The team is led by a physiatrist and consists of the patients' family, physiotherapist, occupational therapist, dietician, psychologist, speech therapist, social worker and other consultant specialists as necessary. | Kemal Nas Levent Yazmalar Volkan ?ah Abdulkadir Ayd?n Kadriye ?ne? | 2015 | World Journal of Orthopedics2015，6，1： | 23 |
| 2 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 3 | Prevalence and virological profiles of hepatitis B infection in human immunodeficiency virus patients显示文摘AIM: To determine the prevalence of hepatitis B virus (HBV) in adult human immunodeficiency virus (HIV) patients with CD4+ T-cell count less than 500/mm 3 and without antiretroviral therapy; to describe different HBV-HIV coinfection virological profiles; and to search for factors associated with HBs antigen (HBsAg) presence in these HIV positive patients.METHODS: During four months (June through September 2006), 491 patients were received in four HIV positive monitoring clinical centers in Abidjan. Inclusion criteria: HIV-1 or HIV-1 and 2 positive patients, age ≥ 18 years, CD4+ T-cell count < 500/mL and formal and signed consent of the patient. Realized blood tests included HIV serology, CD4+ T-cell count, quantitative HIV RNA load and HBV serological markers, such as HBsAg and HBc antibody (anti-HBcAb). We performed HBeAg, anti-HBe antibody (anti-HBeAb), anti-HBc IgM and quantitative HBV DNA load in HBsAg positive patients. Anti-HBsAb had been tested in HIV patients with HBsAg negative and anti-HBcAb-positive. HBV DNA was also tested in 188 anti-HBcAb positive patients with HBsAg negative status and without anti-HBsAb. Univariate analysis (Pearsonχ 2 test or Fischer exact test) and multivariate analysis (backward step-wise selection logistic regression) were performed as statistical analysis. RESULTS: Mean age of 491 patients was 36 ± 8.68 years and 73.3% were female. Type-1 HIV was found in 97% and dual-type HIV (type 1 plus type 2) in 3%. World Health Organization (WHO) clinical stage was 1, 2, 3 and 4 respectively in 61 (12.4%), 233 (47.5%), 172 (35%) and 25 patients (5.1%). Median CD4+ T-cell count was 341/mm 3 (interquartile range: 221-470). One hundred and twelve patients had less than 200 CD4+ T-cell/mm 3 . Plasma HIV-1 RNA load was elevated (≥ 5 log 10 copies/mL) in 221 patients (45%). HBsAg and anti-HBcAb prevalence was respectively 13.4% and 72.9%. Of the 66 HBsAg positive patients, 22 were inactive HBV carriers (33.3%), 21 had HBeAg positive hepatitis (31.8%) and 20 had HBeAg negative hepatitis (30.3%). HBeAg and anti-HBeAb were indeterminate in 3 of them. Occult B infection prevalence (HBsAg negative, anti-HBcAb positive, anti-HBsAb negative and detectable HBV DNA) was 21.3%. Three parameters were significantly associated with the presence of HBsAg: male [odds ratio (OR): 2.2;P = 0.005; 95% confidence interval (CI): 1.3-3.8]; WHO stage 4 (OR: 3.2;P = 0.01;95% CI: 1.3-7.9); and aspartate aminotransferase (AST) level higher than the standard (OR: 1.9;P = 0.04; 95% CI: 1.02-3.8). CONCLUSION: HBV infection prevalence is high in HIV-positive patients. HBeAg positive chronic hepatitis and occult HBV infection are more frequent in HIVpositive patients than in HIV negative ones. Parameters associated with HBsAg positivity were male gender, AIDS status and increased AST level. | Koffi Alain Attia Serge Eholié Eugène Messou Christine Danel Sandrine Polneau Henri Chenal Thomas Toni Myreille Mbamy Catherine Seyler Naomi Wakasugi Thérèse N'dri-Yoman Xavier Anglaret | 2012 | World Journal of Hepatology2012，4，7： | 4 |
| 4 | The Asian Lineage of Zika Virus: Transmission and Evolution in Asia and the Americas显示文摘Since first isolation in 1947 from the Zika forest in Uganda, Zika virus(ZIKV) has been principally known as a benign agent associated with sporadic human infections in a restricted number of African countries. However, during 2015–2016,an Asian lineage of ZIKV caused an unprecedentedly large outbreak in the Americas and sizeable numbers of exported cases across the globe. In this review, we critically appraise the recent advances in molecular epidemiological studies of ZIKV performed to date, and we highlight the pivotal role played by genomic surveillance in elucidating the origins,dissemination and evolution of the Asian lineage of ZIKV in Asia and in the Americas. | Tao Hu Juan Li Michael J.Carr Sebastián Duchêne Weifeng Shi | 2019 | Virologica Sinica2019，34，1： | 3 |
| 5 | Phosphorus sorption experiments and the potential for internal phosphorus loading in littoral areas of a stratified lake显示文摘 | Hélène Cyr Shelley K. McCabe Gertrud K. Nürnberg | 2009 | Water Research2009，，6： | 2 |
| 6 | Continuous quality and shelf life monitoring of retail-packed fresh cod loins in comparison with conventional methods显示文摘 | Nga T.T. Mai María Gudjónsdóttir Hélène L. Lauzon Kolbrún Sveinsdóttir Emilía Martinsdóttir Hubert Audorff Werner Reichstein Dietrich Haarer Sigurdur G. Bogason Sigurjón Arason | 2010 | Food Control2010，，6： | 2 |
| 7 | Arginine in asthma and lung inflammation显示文摘 | King NE Rothenberg ME Zimmermann N | 2004 | J Nutr2004，134，10： | 1 |
| 8 | PD-L2 is expressed on activated human T cells and regulates their function显示文摘 | Messal N Serriari NE Pastor S | 2011 | Mol Immunol2011，48，1516： | 1 |
| 9 | Post transfusion non- cardiogenic pulmonary edema in a patient with chemotherapy-re- lated hemolytic uremic syndrome显示文摘 | Kluger N J Cummings FJ Ready NE | 1998 | Med Health RI1998，81，7： | 1 |
| 10 | Postnatal malnutrition and growth retardation:an inevitable consequence of current recommendations in preterm infants? 显示文摘 | Embleton NE Pang N Cooke RJ | 2001 | Pediatrics2001，107，2： | 1 |
| 11 | Epidemiology and outcome of severe pneumococcal pneumonia admitted to intensive care unit:a multicenter study显示文摘 | Mongardon N Max A BougléA Pène F | 2012 | Crit Care2012，16，4： | 1 |
| 12 | Postnatal malnutritionand grow retardation:an inevitable consequence of carrent iecommendationa in pretem infants?显示文摘 | Embleton NE Pang N Cooke RJ | 2005 | Pediatrics2005，23，： | 1 |
| 13 | P upi l - spa r i ng,painless compression of the oculomotor nerve byexpanding basilar artery aneurysm: a case of ocularpseudomyasthenia显示文摘 | Ajt a i B Fi ne EJ Li ncof f N | 2004 | Arch Neurol2004，61，： | 1 |
| 14 | Herpes simplex encephalitis treated with acyclovir: diagnosis and long term outcome显示文摘 | McGrath N Anderson NE Croxson MC | 1997 | J Neurol Neurosurg Psychiatry1997，63，3： | 1 |
| 15 | Herpes simplex encephalitis treated with acyclovir:Diagnosis and long term outcome显示文摘 | Anderson NE Croxson MC | 1997 | J Neurol Neurosurg Psychiatry1997，63，3： | 1 |
| 16 | Genetics of spherocytosis显示文摘 | Morton NE MacKinney AA Kosower N | 1962 | Am J Hum Genet1962，14，： | 1 |
| 17 | Multiparametric imaging of biological systems by force-distance curve-based AFM显示文摘 | Dufrêne YF Martínez-Martín D Medalsy I Alsteens D Müller DJ | | 0，，： | 1 |
| 18 | Intensive care unit-acquired stenotrophomonas maltophilia:Incidence,risk factors and outcome显示文摘 | Saad N Christophe DP Hélène B | 2006 | Critical Care2006，10，： | 1 |
| 19 | Altera- tions in functional connectivity between the hippocampus and prefrontal cortex as a correlate of depressive symptoms in temporal lobe epilepsy显示文摘 | Kemmotsu N Kucukboyaei NE Cheng CE | 2013 | Epilepsy Behavior2013，29，3： | 1 |
| 20 | Postnatal malnutrition and growth retardation:an inevitable consequence of current recommendations in preterm infants? 显示文摘 | Embleton NE Pang N Cooke UJ el al | 2001 | Pediatrics2001，107，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员