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| 1 | Autologous CD34^+ and CD133^+ stem cells transplantation in patients with end stage liver disease显示文摘AIM:To assess the utility of an autologous CD34 + and CD133 + stem cells infusion as a possible therapeutic modality in patients with end-stage liver diseases.METHODS:One hundred and forty patients with endstage liver diseases were randomized into two groups.Group 1,comprising 90 patients,received granulocyte colony stimulating factor for five days followed by autologous CD34 + and CD133 + stem cell infusion in the portal vein.Group 2,comprising 50 patients,received regular liver treatment only and served as a control group.RESULTS:Near normalization of liver enzymes and improvement in synthetic function were observed in 54.5% of the group 1 patients;13.6% of the patients showed stable states in the infused group.None of the patients in the control group showed improvement.No adverse effects were noted.CONCLUSION:Our data showed that a CD34 + and CD133 + stem cells infusion can be used as supportive treatment for end-stage liver disease with satisfactory tolerability. | Hosny Salama Abdel-Rahman N Zekri Abeer A Bahnassy Eman Medhat Hanan A Halim Ola S Ahmed Ghada Mohamed Sheren A Al Alim Ghada M Sherif | 2010 | World Journal of Gastroenterology2010，16，42： | 16 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | 尼日利亚博尔努盆地沉积地层分布特征显示文摘利用博尔努盆地内23口探井的钻井、测井资料,借助于Excel、Petrel及Surfer等软件,确定了盆地Kerri-Kerri组、Gombe组、Fika组、Gongila组和Bima组及整个沉积地层的空间分布。对整个沉积地层空间分布研究发现,博尔努盆地共有3个主要坳陷(A、C、D)和1个构造高点B。坳陷A位于盆地东北部,坳陷C和D分别位于盆地东南部和西南部,构造高点B分隔坳陷A和坳陷C。Kerri-Kerri组、Gombe组、Fika组、Gongila组和Bima组在盆地广泛分布,但地层厚度存在变化;3口深层探井(Kadaru-1井、Herwa-1井及Kinasar-1井)仅钻揭Bima组上部层段(岩性为中—粗粒长石砂岩),对Bima组下部层段尚未钻遇。因此建议针对盆地内部的潜在含油气坳陷区开展深层钻探。 | Olabode Solomon O Adekoya John A Ola Peter S | 2015 | 石油勘探与开发2015，42，5： | 2 |
| 4 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 5 | Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model显示文摘AIM: To develop a mathematical model for the early detection of hepatocellular carcinoma(HCC) with a panel of serum proteins in combination with α-fetoprotein(AFP).METHODS: Serum levels of interleukin(IL)-8, soluble intercellular adhesion molecule-1(s ICAM-1), soluble tumor necrosis factor receptor Ⅱ(s TNF-RⅡ), proteasome, and β-catenin were measured in 479 subjects categorized into four groups:(1) HCC concurrent with hepatitis C virus(HCV) infection(n = 192);(2) HCV related liver cirrhosis(LC)(n = 96);(3) Chronic hepatitis C(CHC)(n = 96); and(4) Healthy controls(n = 95). The R package and different modules for binary and multi-class classifiers based on generalized linear models were used to model the data. Predictive power was used to evaluate the performance of the model. Receiver operating characteristic curve analysis over pairs of groups was used to identify the best cutoffs differentiating the different groups. RESULTS: We revealed mathematical models, based on a binary classifier, made up of a unique panel of serum proteins that improved the individual performance of AFP in discriminating HCC patients from patients with chronic liver disease either with or without cirrhosis. We discriminated the HCC group from the cirrhotic liver group using a mathematical model(-11.3 + 7.38 × Prot + 0.00108 × s ICAM + 0.2574 ×β-catenin + 0.01597 × AFP) with a cutoff of 0.6552, which achieved 98.8% specificity and 89.1% sensitivity. For the discrimination of the HCC group from the CHC group, we used a mathematical model [-10.40 + 1.416 × proteasome + 0.002024 × IL + 0.004096 × s ICAM-1 +(4.251 × 10-4) × s TNF + 0.02567 ×β-catenin + 0.02442 × AFP] with a cutoff 0.744 and achieved 96.8% specificity and 89.7% sensitivity. Additionally, we derived an algorithm, based on a binary classifier, for resolving the multi-class classification problem by using three successive mathematical model predictions of liver disease status. CONCLUSION: Our proposed mathematical model may be a useful method for the early detection of different statuses of liver disease co-occurring with HCV infection. | Abdel-Rahman Nabawy Zekri Amira Salah El-Din Youssef Yasser Mabrouk Bakr Reham Mohamed Gabr Ola Sayed Ahmed Mostafa Hamed Elberry Ahmed Mahmoud Mayla Mohamed Abouelhoda Abeer A Bahnassy | 2016 | World Journal of Gastroenterology2016，22，16： | 2 |
| 6 | Analysis of sigma receptor( sigmaR1 ) expression in reti- nal ganglion cells cultured under hyperglycemic conditions and in diabetic mice 显示文摘 | Ola MS Martin PM Maddox D EI-Sherbeny A Huang W Roon P | 2002 | Brain Res Mol Brain Res2002，107，2： | 1 |
| 7 | Food intake of the brominated flame retardants PBDEs and HBCD in Sweeden显示文摘 | LIND Y AUNE M ATUMA S BECKER W BJERSELIUS R GLYNN A OLA DARNERUD P | 2002 | Organohalog Compd2002，58，： | 1 |
| 8 | Aroma quality evaluation of strawberry cultivars in southern Spain显示文摘 | Perez A G Sanz C Olias R Rios J J Olas J M | 1997 | Acta Horticulturae1997，439，1： | 1 |
| 9 | Impact of postnatal depression On infantsy growth in Nigeria 显示文摘 | Adewuya A Ola B Aloba 0 | 2008 | Journal of Affective Disorders2008，108，12： | 1 |
| 10 | In search of the optimal oxygen saturation for extremely low birttl weight infants: a systematic review and meta-analysis 显示文摘 | Ola DS Dagfinn A | 2011 | Neonatology2011，100，9： | 1 |
| 11 | A study of linear fric-tion weld microstracture in single crystal CMSX -486 super-alloy 显示文摘 | Ola 0 T Ojo O A Wanjara P | 2012 | Metallurgical and Materials Transactions A2012，43，： | 1 |
| 12 | Ceramic Technology of the Asurini do Xingu, Brazil : An Ethnoarchaeological Study of Artifact Variability显示文摘 | Fabíola Andréa Silva | 2008 | Journal of Archaeological Method and Theory2008，，3： | 1 |
| 13 | Ultrasoundguided hydrosalpinx aspiration during oocyte collection improves pregnancy outcome in IVF:a randomized controlled trial显示文摘 | Hammadieh N Coomarasamy A Ola B | 2008 | Hum Reprod2008，23，： | 1 |
| 14 | Relationship between Depression and Quality of Life in Persons with HIV Infection in Nigeria显示文摘 | Adewuya A O Afolabi M O Ola B A | 2008 | Int J Psychiatry Med2008，38，1： | 1 |
| 15 | miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cance r显示文摘 | Gallardo E Navarro A Vi ii olas N | 2009 | Carcinogenesis2009，，： | 1 |
| 16 | Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells显示文摘 | BRIDGE C C OLA M S PRASAD P D EISHERBENY A GANAPATHY V SMITH S B | 2001 | Am J Physiol Cell Physiol2001，281，6： | 1 |
| 17 | The oxidative stress may be induced by the elevated homocysteine in schizophrenic patients显示文摘 | Dietrich-Muszalska A Malinowska J Olas B | 2012 | Neurochem Res2012，37，5： | 1 |
| 18 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 1 |
| 19 | Storage life of Croaker (Pseudotholitus senegalensis ) in ice and ambient temperature 显示文摘 | OLA BABAJIDE J OLADIPO A | 2004 | African Journal of Biomedical Research2004，7，1： | 1 |
| 20 | Ultrasound-guided hydrosalpinx aspiration during oocyte collection improves pregnan- cy outcome in IVF: a randomized controlled trial 显示文摘 | Hammadieh N Coomarasamy A Ola B | 2008 | Hum Re- prod2008，23，5： | 1 |
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