|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Perioperative anemia management in colorectal cancer patients:A pragmatic approach显示文摘Anemia,usually due to iron deficiency,is highly prevalent among patients with colorectal cancer.Inflammatory cytokines lead to iron restricted erythropoiesis further decreasing iron availability and impairing iron utilization.Preoperative anemia predicts for decreased survival.Allogeneic blood transfusion is widely used to correct anemia and is associated with poorer surgical outcomes,increased post-operative nosocomial infections,longer hospital stays,increased rates of cancer recurrence and perioperative venous thromboembolism.Infections are more likely to occur in those with low preoperative serum ferritin level compared to those with normal levels.A multidisciplinary,multimodal,individualized strategy,collectively termed Patient Blood Management,minimizes or eliminates allogeneic blood transfusion.This includes restrictive transfusion policy,thromboprophylaxis and anemia management to improve outcomes.Normalization of preoperative hemoglobin levels is a World Health Organization recommendation.Iron repletion should be routinely ordered when indicated.Oral iron is poorly tolerated with low adherence based on published evidence.Intravenous iron is safe and effective but is frequently avoided due to misinformation and misinterpretation concerning the incidence and clinical nature of minor infusion reactions.Serious adverse events with intravenous iron are extremely rare.Newer formulations allow complete replacement dosing in 15-60 min markedly facilitating care.Erythropoiesis stimulating agents may improve response rates.A multidisciplinary,multimodal,individualized strategy,collectively termed Patient Blood Management used to minimize or eliminate allogeneic blood transfusion is indicated to improve outcomes. | Manuel Muoz Susana Gómez-Ramírez Elisa Martín-Montaez Michael Auerbach | 2014 | World Journal of Gastroenterology2014，20，8： | 8 |
| 2 | Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response. | Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu | 2016 | World Journal of Gastrointestinal Oncology2016，8，9： | 3 |
| 3 | Intravenous iron in inflammatory bowel disease显示文摘The prevalence of anemia across studies on patients with inflammatory bowel disease (IBD) is high (30%). Both iron defi ciency (ID) and anemia of chronic disease contribute most to the development of anemia in IBD. The prevalence of ID is even higher (45%). Anemia and ID negatively impact the patient's quality of life. Therefore, together with an adequate control of disease activity, iron replacement therapy should start as soon as anemia or ID is detected to attain a normal hemoglobin (Hb) and iron status. Many patients will respond to oral iron, but compliance may be poor, whereas intravenous (IV) compounds are safe, provide a faster Hb increase and iron store repletion, and presents a lower rate of treatment discontinuation. Absolute indications for IV iron treatment should include severe anemia, intolerance or inappropriate response to oral iron, severe intestinal disease activity, or use of an erythropoietic stimulating agent. Four different products are principally used in clinical practice, which differ in their pharmacokinetic properties and safety profi les: iron gluconate and iron sucrose (lower single doses), and iron dextran and ferric carboxymaltose (higher single doses). After the initial resolution of anemia and the repletion of iron stores, the patient's hematological and iron parameters should be carefully and periodically monitored, and maintenance iron treatment should be provided as required. New IV preparations that allow for giving 1000-1500 mg in a single session, thus facilitating patient management,provide an excellent tool to prevent or treat anemia and ID in this patient population, which in turn avoids allogeneic blood transfusion and improves their quality of life. | Manuel Muoz Susana Gómez-Ramírez José Antonio García-Erce | 2009 | World Journal of Gastroenterology2009，15，37： | 2 |
| 4 | Longerm outcome of twintwin transfusion treated with serial aggressive amnin reduction 显示文摘 | Mari G Detti L Oz U | 2003 | Arn J Obstet Gynecol2003，183，1： | 1 |
| 5 | Role of the nitric oxide pathway on ischemia - reperfusion injury in an isolated perfused guinea pig heart 显示文摘 | Oz E Arsakay G Dineer S | 2000 | Gen Pharmacol2000，34，1： | 1 |
| 6 | Reboxetine ad-junct for partial or nonresponders to antidepressant treat-ment显示文摘 | Rubio G San L Lapez-Mu oz F | 2004 | J Affect Disord2004，81，1： | 1 |
| 7 | Long-term outcome twin-twin transfusion treated with serial aggressive amnioreduction显示文摘 | Detti L Oz U | 2000 | Am J Obstet Gynecol2000，183，1： | 1 |
| 8 | Reactive dividing wall distillation columns: simulation and implementation in a pilot plant显示文摘 | Hernández S Sandoval-Vergara R Barroso-Mu?oz F O Murrieta-Due?as R Hernández-Escoto H Segovia-Hernández J G Rico-Ramirez V | 2009 | Chemical Engineering and Processing2009，48，1： | 1 |
| 9 | Deep intubation of 6 French guiding catheters for transradial coronary interventions显示文摘 | yon Sohosten R Oz R Marone G | 1998 | J Invasive Cardiol1998，10，4： | 1 |
| 10 | An alternative method for splinting of traumatized teeth: case reports 显示文摘 | Yildirim Oz G Atao lu H | 2006 | Dent Traumatol2006，22，6： | 1 |
| 11 | RNA-Seq analysis using De Novo Transcriptome Assembly as a reference for the Salmon Louse Caligus rogercresseyi显示文摘 | Gallardo-Escárate C Valenzuela-Mu(n)oz V Nu(n)ez-Acu(n)a G | 2014 | PLOSONE2014，9，92： | 1 |
| 12 | Effectiveness and safety of simplification from tenofovir-lamivudine (TDF-3TC) to tenofovir-emtricitabine (TDF-FTC) co-formulation (Truvada?) in virologically suppressed HIV-infected patients on HAART显示文摘 | R. Palacios C. Hidalgo M. J. Ríos A. Rivero L. Mu?oz F. Lozano V. Gutiérrez-Ravé M. C. Gálvez A. Arco J. Santos | 2009 | European Journal of Clinical Microbiology & Infectious Diseases2009，，4： | 1 |
| 13 | A prospective,randomized comparison between ultrasound-guided supraclavicular,infraclavicular,and axillary brachial plexus blocks显示文摘 | Tran de QH Russo G Mu?oz L | 2009 | Reg Anesth Pain Med2009，34，4： | 1 |
| 14 | A novel poly(N-isopropylacrylamide- co-N-hydroxymethyl acrylamide) gel: Preparation in the ab- sence/presence of a pore-forming agent and characterization 显示文摘 | GURDAG G OZ G M | 2009 | Polym Adv Technol2009，20，3： | 1 |
| 15 | Long-term outcome in twin-twin transfusion syndrome treated with serial aggressive amnioreduction 显示文摘 | Detti L Oz U | 2000 | Am J Obstet Gyneco12000，183，1： | 1 |
| 16 | Evaluating the Polyphenol Profile in Three Segregating Grape ( Vitis vinifera L.) Populations显示文摘 | Alberto Hernández-Jiménez Rocío Gil-Mu?oz Yolanda Ruiz-García Jose María López-Roca Adrián Martinez-Cutillas Encarna Gómez-Plaza Shixin Deng | 2013 | <journal-title>Journal of Analytical Methods in Chemistry2013，，： | 1 |
| 17 | Oxidative dim-enzation in metallothionein is a result of inter-molecular disulphide bonds between cysteins in the domain 显示文摘 | ZANGGER K SHEN G Oz G | 2001 | Biochem J2001，359，2： | 1 |
| 18 | Higher-order cumulants and spectral kurtosis for early detection of subterranean termites 显示文摘 | De la Rosa J J G Mu~oz A M | 2008 | Mechanical Systems and Signal Processing2008，22，1： | 1 |
| 19 | Assessment of adrenoleukodystrophy lesions by high field MRS in non-sedated pediatric patients显示文摘 | Oz G Tkác I Charnas LR | 2005 | Neurology2005，64，3： | 1 |
| 20 | Could remembering the prozone phenomenon shorten our diagnostic journey in brucellosis 显示文摘 | GUVEN G S CAKIR B OZ G | 2006 | Rheumatol Int2006，26，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员