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| 1 | Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study显示文摘High-frequency ultrasound imaging can provide exquisite visualizations of tissue to guide minimally invasive procedures.Here,we demonstrate that an all-optical ultrasound transducer,through which light guided by optical fibers is used to generate and receive ultrasound,is suitable for real-time invasive medical imaging in vivo.Broad-bandwidth ultrasound generation was achieved through the photoacoustic excitation of a multiwalled carbon nanotube-polydimethylsiloxane composite coating on the distal end of a 300-μm multi-mode optical fiber by a pulsed laser.The interrogation of a high-finesse Fabry–Pérot cavity on a single-mode optical fiber by a wavelength-tunable continuous-wave laser was applied for ultrasound reception.This transducer was integrated within a custom inner transseptal needle(diameter 1.08 mm;length 78 cm)that included a metallic septum to acoustically isolate the two optical fibers.The use of this needle within the beating heart of a pig provided unprecedented realtime views(50 Hz scan rate)of cardiac tissue(depth:2.5 cm;axial resolution:64μm)and revealed the critical anatomical structures required to safely perform a transseptal crossing:the right and left atrial walls,the right atrial appendage,and the limbus fossae ovalis.This new paradigm will allow ultrasound imaging to be integrated into a broad range of minimally invasive devices in different clinical contexts. | Malcolm C Finlay Charles A Mosse Richard J Colchester Sacha Noimark Edward Z Zhang Sebastien Ourselin Paul C Beard Richard J Schilling Ivan P Parkin Ioannis Papakonstantinou Adrien E Desjardins | 2017 | Light(Science & Applications)2017，6，1： | 6 |
| 2 | The metabolic syndrome显示文摘 | Robert H Eckel KGMM Alberti Scott M Grundy Paul Z Zimmet | 2010 | The Lancet2010，，9710： | 4 |
| 3 | Phytochemical constituents and antibacterial efficacy of the flowers of Peltophomm pterocarpum(DC.) Baker ex Heyne显示文摘Objective:To investigate the preliminary phytochemistry and antibacterial activity of the flower extract of Peltophorum pterocarpum.Methods:Phytochemical analysis was done by using the standard methods given by Harbone.The methanolic flower extract were tested against Escherichia coli,Klebsiella pneumonia,Pseudomonas aeruginosa.Staphylococcus aureus. Bacillus cereus,Salmonella typhi,Serratia marsecens,Acinetobacter baumannii.Enterobacter sp., Proteus mirabilis.Enterococcus faecalis and Streptococcus pyogenes by the agar disc diffusion method.Results:Preliminary phytochemical screening of flower extract showed the presence of phenolic compounds,flavonoids.saponins,steroids,tannins,xanthoproteic,carboxylic acids, coumarins and carbohydrates.The flower extract of Peltophorum pteroearpum showed significant activity against four gram positive(Staphylococcus aureus.Bacillus cereus.Enlerococcus faecalis and Streptococcus pyogenes) and three gram negative bacteria(Proteus mirabilis,Acinetohacter baumannii and Serratia marsecens).out of 12 pathogenic bacteria studied.Conclusion:The findings of the present study confirm the presence of significant antibacterial activity against human pathogens in the flowers of Peltophorum pleracarpum. | Sukumaran S Kiruba S Mahesh M Nisha SR Miller Paul Z Ben CP Jeeva S | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，9： | 4 |
| 4 | The metabolic syndrome显示文摘 | Robert H Eckel Scott M Grundy Paul Z Zimmet | 2005 | The Lancet2005，，9468： | 2 |
| 5 | The metabolic syndrome显示文摘 | Robert H Eckel KGMM Alberti Scott M Grundy Paul Z Zimmet | 2010 | 2010 (9710)2010，，9710： | 2 |
| 6 | Solid-state ^15N NMR study of N labelled polyaniline upon reaction with DPPH显示文摘 | ZORAN D Z MARIJA R G PAUL A K | 2006 | Polymer2006，47，： | 1 |
| 7 | A new Neotyphodium species symbiotic with drunken horse grass (Achnatherum inbrians)in China 显示文摘 | Li C J Nan Z B Paul V H | 2004 | Myotaxon2004，90，1： | 1 |
| 8 | Control of gear shifts in dual dutch transmission powertrains 显示文摘 | PAUL D W NONG Z RICHARD T | 2011 | Mechanical Systems and Signal Processing2011，25，6： | 1 |
| 9 | Our wormy world genomics, pro- teomics and transcriptomics in East and southeast Asia显示文摘 | Ju C Feng Z Paul J B | 2010 | Adv Parasitol2010，73，： | 1 |
| 10 | Alow resistance boron-doped carbon nanotube-polystyrene composite显示文摘 | Paul C P Watts Wen Kuang Hsu George Z Chen | 2001 | J Mater Chem2001，11，： | 1 |
| 11 | Risk matrix: An approach for identifying, assessing, and ranking program risks 显示文摘 | Paul R Garvey P R Landsdowne Z F | 1998 | Air Force Journal of Logistics1998，25，： | 1 |
| 12 | Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction显示文摘 | Roula A Farah Khalil S Jalkh Hussein Z Farhat Paul E Sayad Adel M Kadri | 2011 | Blood Coagulation & Fibrinolysis2011，，2： | 1 |
| 13 | Risk matrix: an approach for identifying, assessing, and ranking program risks 显示文摘 | Paul R Garvey P R Lansdowne Z F | 1998 | Air Journal of Logistics1998，，25： | 1 |
| 14 | Competitive and cooperative inventory policies in a two stage supply chain显示文摘 | GERARD P C PAUL H Z | 1999 | Management Science1999，45，7： | 1 |
| 15 | Modelling of dual clutch transmission e- quipped powertrains for shift transient simulations 显示文摘 | PAUL D W NONG Z | 2013 | Mechanism and Machine Theory2013，60，： | 1 |
| 16 | Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrialcarcinomas of the endometrioid type显示文摘 | Israel Z Paul J G Feng G | 2007 | J Clin Oncol2007，25，15： | 1 |
| 17 | Major bile duct injuries after laparoscopic cholecystectomy: A tertiary center experience显示文摘 | Andrea Frilling M.D. Ph.D. Jun Li M.D. Frank Weber M.D. Nils Roman Frühauf M.D. Jennifer Engel Susanne Beckebaum M.D. Andreas Paul M.D. Thomas Z?pf M.D. Massimo Malago M.D. Ph.D. Christoph Erich Broelsch M.D. Ph.D | 2004 | Journal of Gastrointestinal Surgery2004，，6： | 1 |
| 18 | Backward-mode multiwavelength photoacoustic scanner using a planar Fabry-Perot polymer film ultrasound sensor for high-resolution three-dimensional imaging of biological tissues显示文摘 | Eduward Z Jan L Paul B | 2008 | Applied Optics2008，47，4： | 1 |
| 19 | Prediction of fatigue crack growth in steel bridge components using acoustic emission显示文摘 | Jianguo Yu Paul Ziehl Boris Zárate Juan Caicedo | 2011 | Journal of Constructional Steel Research2011，，8： | 1 |
| 20 | Amelioration of marine farming impact on the benthic environment using artificial reefs as biofilters显示文摘 | GAO Q F PAUL K S XU W Z | 2008 | Marine Pollution Bulletin2008，57，： | 1 |
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