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| 1 | High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound显示文摘AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation. | Roman Schumann Nikola S Natov Klifford A Rocuts-Martinez Matthew D Finkelman Tom V Phan Sanjay R Hegde Robert M Knapp | 2016 | World Journal of Gastroenterology2016，22，47： | 9 |
| 2 | Lanreotide in Metastatic Enteropancreatic Neuroendocrine Tumors显示文摘 | Martyn E. Caplin Marianne Pavel Jaros?aw B. ?wik?a Alexandria T. Phan Markus Raderer Eva Sedlá?ková Guillaume Cadiot Edward M. Wolin Jaume Capdevila Lucy Wall Guido Rindi Alison Langley Séverine Martinez Jo?lle Blumberg Philippe Ruszniewski | 2014 | The New England Journal of Medicine2014，，： | 3 |
| 3 | Improved quarter-point crack tip element显示文摘 | GRAY L J PHAN A V PAULINO G H | 2003 | Engineering Fracture Mechanics2003，70，： | 1 |
| 4 | High-throughput synthesis of zeolitic imidazolate frameworks and application to CO2 capture显示文摘 | Banerjee R Phan A Wang B | 2008 | Science2008，319，5865： | 1 |
| 5 | One hundred years after 'careinoid' : epidemiologe of and prognostic factors for neu- ro-endocrine tumors in 35,825 cases in the United States 显示文摘 | Yao J C Hassan M Phan A | 2008 | Clin Oncol2008，26，18： | 1 |
| 6 | Milk-clotting enzymes pro- duced by culture of Bacillus su, btilis natto 显示文摘 | Shieh C H Phan Thi L A Shih I L | 2009 | Biochemical Engi- neering Journal2009，43，： | 1 |
| 7 | A meta-analysis of mini- mally invasive versus conventional sternotomy for aortic valve replacement 显示文摘 | Phan K Xie A Di Eusanio M | 2014 | Ann Thorac Surg2014，98，4： | 1 |
| 8 | Berk A 90-kD Na+-H+ exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells显示文摘 | Phan V N Kusuhara M Lucchesi P A | 1997 | Hypertention1997，29，6： | 1 |
| 9 | Interference in determination of ammonia with the hypochlorite-alkaline phenol method of berthelot 显示文摘 | Ngo T T Phan A P H Yam C F | 1982 | Analytical Chemistry1982，54，1： | 1 |
| 10 | Finite element and experimental studies of diameter errors in cantilever bar turning 显示文摘 | PHAN A V BARON L MAYER J | 2003 | Applied Mathematical Modeling2003，，27： | 1 |
| 11 | Phase equilibria and thermodynamics of the Fe-A1-C system: Critical evaluation, experiment and thermodynamic optimization显示文摘 | PHAN A T PAEK M K KANG Y B | 2014 | Acta Materialia2014，79，： | 1 |
| 12 | Biological variability of sperm DNA denaturation in infertile men显示文摘 | Zini A Kamal K Phan D et a l | 2001 | Urology2001，58，2： | 1 |
| 13 | High-throughput synthesis of zeolitic imidazolate frameworks and applica- tion to CO2 capture 显示文摘 | Banerjee R Phan A Wang B | 2008 | Science2008，319，： | 1 |
| 14 | Effect of extendedsurfactant structure on interfacial tension and microemulsionformation with triglycerides 显示文摘 | Phan T T Attaphong C Sabatini D A | 2011 | Journal of the American OilChemists Society2011，88，8： | 1 |
| 15 | One hundred years after 'carcinoid': epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States显示文摘 | Yao JC Hassan M Phan A | 2008 | J Clin Oncol2008，26，18： | 1 |
| 16 | Human skin keloid fibroblasts display bioenergetics of cancer cells显示文摘 | VINCENT AS PHAN TT MUKHOPADHYAY A | 2008 | J Invest Dermatol2008，128，3： | 1 |
| 17 | Hypertrophic scar fibroblasts have increased Connective tissue growth factor expression after transforming growth factor-stimulation 显示文摘 | Colwell A S Phan T T Kong W | 2005 | Plas t Recons tr Surg2005，116，5： | 1 |
| 18 | Hypertrophic scar fibroblasts have increased connective tissue growth factor expression after transforming growth factor-beta stimulation 显示文摘 | Colwell A S Phan T T Kong W | 2005 | Plast Reconstr Surg2005，116，5： | 1 |
| 19 | 查看详情显示文摘 | Tran U P N Le K K A Phan N T S | | 0，，02： | 1 |
| 20 | Human skin keloid fibroblasts display bioenergetics of cancer cells 显示文摘 | Vincent AS Phan TT Mukhopadhyay A | 2008 | J Invest Dermatol2008，128，： | 1 |
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