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| 1 | 慢性肾脏病中的炎症和动脉硬化:慢性肾功能不全队列研究中的发现显示文摘慢性肾脏病(chronic kidney disease,CKD)和动脉硬化程度与心血管病发病率和死亡率增加相关。目前认为炎症在动脉硬化发展中发挥作用,而CKD被认为是一种促炎症反应的状态。CKD患者的动脉僵硬度增加,横断面数据提示CKD中增多的炎症标志物与较高动脉僵硬度值相关。 | Peyster E Chen J Feldman HI Go AS Gupta J Mitra N Pan Q Porter A Rahman M Raj D Reilly M Wing MR Yang W Townsend RR 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，11： | 12 |
| 2 | New therapeutic opportunities for Hepatitis C based on small RNA显示文摘Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease, including cirrhosis and liver cancer and is therefore, the most common indication for liver transplantation. Conventional antiviral drugs such as pegylated interferon-alpha, taken in combination with ribavirin, represent a milestone in the therapy of this disease. However, due to different viral and host factors, clinical success can be achieved only in approximately half of patients, making urgent the requirement of exploiting alternative approaches for HCV therapy. Fortunately, recent advances in the understanding of HCV viral replication and host cell interactions have opened new possibilities for therapeutic intervention. The most recent technologies, such as small interference RNA mediated gene-silencing, anti-sense oligonucleotides (ASO), or viral vector based gene delivery systems, have paved the way to develop novel therapeutic modalities for HCV. In this review, we outline the application of these technologies in the context of HCV therapy. In particular, we will focus on the newly defined role of cellular microRNA (miR-122) in viral replication and discuss its potential for HCV molecular therapy. | Qiu-wei Pan Scot D Henry Bob J Scholte Hugo W Tilanus Harry LA Janssen Luc JW van der Laan | 2007 | World Journal of Gastroenterology2007，13，33： | 4 |
| 3 | Effect of middle cerebral artery occlusion on the passage of pituitary adenylate cyclase activating polypeptide across the blood-brain barrier in the rat显示文摘 | Pan W Relglodi D | 2000 | Regul Peptide2000，91，： | 1 |
| 4 | KCNQ2 and KCNQ3 potassium channel subunits : molecular correlates of M-channel显示文摘 | Wang HS Pan Z Shi W Brown D | 1998 | Science1998，283，5395： | 1 |
| 5 | Haploinsufficiency of delta- like 4 ligand results in embryonic lethality due to ma:or defects in arterial and vascular development显示文摘 | Gale N W Dominguez M G Noguera I Pan L Hughes V Va]enzuela D M | 2004 | Proc Natl Acad Sci USA2004，101，15： | 1 |
| 6 | Rotational micro-motion modulated jamming for countering ISAR based on intermittent sampling repeater显示文摘 | Pan X Y Wang W Feng D J | 2013 | Progress in Electromagnetics Research2013，36，： | 1 |
| 7 | Ligands Dominate Highly Syndioselective Polymerization of Styrene by Using Constrained-geometry-configuration Rare-earth Metal Precursors显示文摘 | Pan Y P Rong W F Cui D M | | 0，，03： | 1 |
| 8 | Stress Oscillations and Surface Alloy Formation during the Growth of FeMn on Cu (100)显示文摘 | Pan W Sander D Lin M T | 2003 | Phys Rev B2003，68，22： | 1 |
| 9 | Design Gabor filters in the frequency domain for unsupervised fabric defect detection显示文摘 | Zhang X Y Pan R R Gao W D | 2011 | Industrial Textilǎ2011，62，4： | 1 |
| 10 | Experimental Quantum Teleportation显示文摘 | BOUWMEESTER D PAN J W MATTLE K | 1997 | Nature1997，，390： | 1 |
| 11 | Architecture- based software reliability modeling显示文摘 | WANG W L PAN D CHEN M H | 2006 | The Journal of Systems and Software2006，79，： | 1 |
| 12 | Europ Polym J显示文摘 | Xu W B Liang G D Zhai H B Tang S P Hang G P Pan W P | 2003 | 39:1 4672003，39，： | 1 |
| 13 | Raman spectral study of silicon nanowires: high order scattering and phonon confinement 显示文摘 | Wang R P Zhou G W Liu Y L Pan S I-I Zhang H Z Yu D P Zhang Z | 2000 | Phys Rev B2000，61，16： | 1 |
| 14 | Study on BaBi4Ti4O15 nanoscaled powders prepared by sol-gel method 显示文摘 | Xie D Pan W | 2003 | Mater Lett2003，57，： | 1 |
| 15 | Experimental quantum teleportation 显示文摘 | BOUWMEESTER D PAN J W MATTLE K | 1997 | Nature1997，390，： | 1 |
| 16 | Fatigue Analysis of Crankshaft Sections under Bending with Consid- eration of Residual Stresses显示文摘 | Chien W Y Pan J Close D | 2005 | International Journal of Fatigue2005，27，： | 1 |
| 17 | Architecture-based soft- ware reliability modeling显示文摘 | WAN G W L PAN D CHEN M H | 2006 | The Journal of Systems and Software2006，79，13： | 1 |
| 18 | Experimental quantum teleportation显示文摘 | Bouwmeester D Pan J W | 1997 | Nature1997，390，： | 1 |
| 19 | Activity of plasma sprayed yttria stabilized zirconia reinforced hydroxyapatite/Ti-6A1--4V composite films in simulated body fluid显示文摘 | Gu Y W IChor K A Pan D | 2004 | Biomaterials2004，25，16： | 1 |
| 20 | Fatigue analysis of crankshaft sections under bending with consideration of residual stresses显示文摘 | Chien W Y Pan J Close D | 2005 | International Journal of Fatigue2005，27，： | 1 |
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