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| 1 | Effects of Saccharomycesboulardiion fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition显示文摘AIM: To assess the effects of Sb on fecal flora and shortchain fatty acids (SCFA) in patients on long-term TEN.METHODS: Ten patients (3 females, 7 males, 59±5.5 years),on TEN for a median of 13 mo (1-125), and 15 healthy volunteers (4 females, 11 males, 32±2.0 years) received Sb (0.5 g bid PO) for 6 d. Two stool samples were taken before, on the last 2 d and 9-10 d after treatment, for SCFA measurement and for culture and bacterial identification.Values (mean±SE) were compared using sign tests and ANOVA.RESULTS: Fecal butyrate levels were lower in patients(10.1±2.9 mmol/kg) than in controls (19.2±3.9, P= 0.02).Treatment with Sb increased total fecal SCFA levels in patients (150.2±27.2 vs 107.5±18.2 mmol/kg, P = 0.02)but not in controls (129.0±28.6 vs 113.0±15.2 mmol/kg,NS). At the end of treatment with Sb, patients had higher fecal butyrate (16.0±4.4 vs 10.1 [2.9] mmol/kg, P = 0.004).Total SCFAs remained high 9 d after treatment was discontinued. Before the treatment, the anaerobe to aerobe ratio was lower in patients compared to controls (2.4±2.3 vs69.8±1.8, P = 0.003). There were no significant changes in the fecal flora of TEN patients.CONCLUSION: Sb-induced increase of fecal SCFA concentrations (especially butyrate) may explain the preventive effects of this yeast on TEN-induced diarrhea. | Stéphane M Schneider Fernand Girard-Pipau Jér(o|^)me Filippi Xavier Hébuterne Dominique Moyse Gustavo Calle Hinojosa Anne Pompei Patrick Rampal | 2005 | World Journal of Gastroenterology2005，11，39： | 26 |
| 2 | Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-1igase signaling effector DWARF3显示文摘 | Li-Hua Zhao X Edward Zhou Wei Yi Zhongshan Wu Yue Liu Yanyong Kang Li Hou Parker W de Waal Suling Li Yi Jiang Adrian Scaffidi Gavin R Flematti Steven M Smith Vinh Q Lam Patrick R Griffin YonghongWang Jiayang Li Karsten Melcher H Eric Xu | 2015 | Cell Research2015，25，11： | 7 |
| 3 | Adenoma detection with cap-assisted colonoscopy versus regular colonoscopy: a randomised controlled trial显示文摘 | Thomas R de Wijkerslooth Esther M Stoop Patrick M Bossuyt Elisabeth M H Mathus-Vliegen Jan Dees Kristien M A J Tytgat Monique E van Leerdam Paul Fockens Ernst J Kuipers Evelien Dekker | 2012 | Gut2012，，10： | 3 |
| 4 | Patterns of genomic and phenomic diversity in wine and table grapes显示文摘Grapes are one of the most economically and culturally important crops worldwide,and they have been bred for both winemaking and fresh consumption.Here we evaluate patterns of diversity across 33 phenotypes collected over a 17-year period from 580 table and wine grape accessions that belong to one of the world’s largest grape gene banks,the grape germplasm collection of the United States Department of Agriculture.We find that phenological events throughout the growing season are correlated,and quantify the marked difference in size between table and wine grapes.By pairing publicly available historical phenotype data with genome-wide polymorphism data,we identify large effect loci controlling traits that have been targeted during domestication and breeding,including hermaphroditism,lighter skin pigmentation and muscat aroma.Breeding for larger berries in table grapes was traditionally concentrated in geographic regions where Islam predominates and alcohol was prohibited,whereas wine grapes retained the ancestral smaller size that is more desirable for winemaking in predominantly Christian regions.We uncover a novel locus with a suggestive association with berry size that harbors a signature of positive selection for larger berries.Our results suggest that religious rules concerning alcohol consumption have had a marked impact on patterns of phenomic and genomic diversity in grapes. | ZoëMigicovsky Jason Sawler Kyle M Gardner Mallikarjuna K Aradhya Bernard H Prins Heidi R Schwaninger Carlos D Bustamante Edward S Buckler Gan-Yuan Zhong Patrick J Brown Sean Myles | 2017 | Horticulture Research2017，4，1： | 3 |
| 5 | Substances toxic to plant-para-sitic nematodes in decomposing plant residue显示文摘 | Sayre R M Patrick Z A Thorpe H | 1964 | Phytopathology1964，54，： | 1 |
| 6 | Influence of extractable iron, aluminum and manganese of P sorption in flooded acid sulfate soils 显示文摘 | Jugsujinda A Krairapanona A Patrick J R W H | 1995 | Biology and Fertility of Soils1995，20，： | 1 |
| 7 | Nitrogen and phosphorus distribution and utilization by Spartina alterniflora in a Louisiana gulf coastal marsh显示文摘 | BURESH R J DELAUNE R D PATRICK W H | 1980 | Estuaries and coasts1980，3，2： | 1 |
| 8 | Sedimentation rates determined by ^137Cs dating in a rapidly accreting salt marsh显示文摘 | Delaune R D Patrick W H Bursch R J | 1978 | Nature1978，275，： | 1 |
| 9 | Nitrification and denitrification at the plant root and sediment interfaces in wetlands显示文摘 | Reddy K R Patrick W H Lindau C W | | 0，，： | 1 |
| 10 | Soil nitrogen loss as a result of alternate sub- mergence and drying显示文摘 | Patrick W H Wyatt R | 1964 | Soil Sci Soc Am J1964，28，5： | 1 |
| 11 | Ownership structure, managerial behavior and corporate value 显示文摘 | Davies J R David H Patrick M | 2005 | Journal of Corporate Finance2005，，4： | 1 |
| 12 | Nitrous oxide emission from Gulf Coast wetlands 显示文摘 | Smith C J DeLaune R D Patrick W H Jr | 1983 | Geochimica et Cosmochimica Acta1983，47，10： | 1 |
| 13 | Phosphate release and sorption by soils and sediments:effect of aerobic and anaerobic conditions显示文摘 | PATRICK W H J KHALID R A | 1974 | Science New Series1974，186，4158： | 1 |
| 14 | Nitrification -deitrification at the plant root - sediment interfaces in wetland 显示文摘 | Reddy K R Patrick J K W H Lindau C W | 1989 | Limnology and Oceanography1989，34，6： | 1 |
| 15 | Dynamics of sediment discharge in relation to land use and hydro-climatol- ogy in a humid tropical watershed in costa rica 显示文摘 | JAGDISH K PATRICK N H DANIEL D R | 2001 | Journal of Hydrology2001，253，14： | 1 |
| 16 | Chernobyl Cs-137 used to determine sediment accretion rates at selected north European coastal wetlands显示文摘 | Callaway J C Delaune R D Patrick W H | 1996 | Limnology and Oceanography1996，41，3： | 1 |
| 17 | Comparison of the Bishop score , ultrasonographically measured cervical length,and fetal fibronectin assay in predicting time until delivery and type of delivery at term显示文摘 | Patrick R Francois G Mahdie H | 2000 | Am J Obstet Gynecol2000，182，2： | 1 |
| 18 | Nitrogen transformation and loss in flooded soils and sediments显示文摘 | REDDY K R PATRICK W H | 1984 | Crit Rev Envir Control1984，13，： | 1 |
| 19 | 查看详情显示文摘 | Schuch R Garibian A Nygaard P Raymond S Araik G Hans H S Patrick J P Per N | | 0，，： | 1 |
| 20 | Aerenchyma formation and methane and oxygen exchange in rice显示文摘 | Kludze H K De Laune R D Patrick W H | 1993 | Soil Science Society of Arnerica Journal1993，57，2： | 1 |
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