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| 1 | 成人自发性脑出血处理指南——2007年更新版:美国心脏协会/美国卒中协会卒中委员会、高血压研究委员会、医疗质量和转归研究跨学科工作组指南:美国神经病学学会确认本指南作为神经科医生教学工具的价值显示文摘目的:本指南旨在为急性自发性脑出血的诊断和治疗提供最新的综合性推荐意见。方法:通过Medline正式检索截止2006年8月的相关文献,并将撰写委员会已知相关问题的其他论文作为补充,用证据表合并资料。采用美国心脏协会卒中委员会的证据水平分级标准对每项推荐意见进行分级。由5位同行评议专家和卒中委员会领导委员会成员对指南草案进行发表前审阅。预期本指南在3年内完全更新。结果:本文陈述了脑出血的诊断、动脉血压和颅内压增高的处理、脑出血内科并发症的治疗以及复发性脑出血的预防等方面的循证指南。对重组Ⅶ因子延缓早期出血的近期试验进行了讨论。对自发性脑出血治疗的各种外科手术方法提出了推荐意见。最后,对脑出血患者的撤销治疗和临终问题进行了分析。 | Joseph Broderick Sander Connolly Edward Feldmann Daniel Hanley Carlos Kase Derk Krieger Marc Mayberg Lewis Morgenstern Christopher S. Ogilvy Paul Vespa Mario Zuccarello 王玉洁(译) 刘娟(译) 白璇(译) 李新辉 孙虹(译) 姚志成(译) 张慧(译) 牛英翔(译) | 2007 | 国际脑血管病杂志2007，15，7： | 234 |
| 2 | 成人自发性脑出血处理指南——2007年更新版 美国心脏协会/美国卒中协会卒中委员会、高血压研究委员会、医疗质量和转归研究跨学科工作组指南 美国神经病学学会确认本指南作为神经科医生教学工具的价值显示文摘目的:本指南旨在为急性自发性脑出血的诊断和治疗提供最新的综合性推荐意见。方法:通过Medline正式检索截止2006年8月的相关文献,并将撰写委员会已知相关问题的其他论文作为补充,用证据表合并资料。采用美国心脏协会卒中委员会的证据水平分级标准对每项推荐意见进行分级。由5位同行评议专家和卒中委员会领导委员会成员对指南草案进行发表前审阅。预期本指南在3年内完全更新。结果:本文陈述了脑出血的诊断、动脉血压和颅内压增高的处理、脑出血内科并发症的治疗以及复发性脑出血的预防等方面的循证指南。对重组Ⅶ因子延缓早期出血的近期试验进行了讨论。对自发性脑出血治疗的各种外科手术方法提出了推荐意见。最后,对脑出血患者的撤销治疗和临终问题进行了分析。 | Joseph Broderick Sander Connolly Edward Feldmann Daniel Hanley Carlos Kase Derk Krieger Marc Mayberg Lewis Morgenstern Christopher S.Ogilvy Paul Vespa Mario Zuccarello 王玉洁 刘娟 白璇 李新辉 孙虹 姚志成 张慧 牛英翔 | 2008 | 中华脑血管病杂志(电子版)2008，2，1： | 29 |
| 3 | Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models显示文摘AIM To assess the performance of BALAD, BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC) patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin, albumin, alpha-fetoprotein(AFP), Lens culinaris agglutinin-reactive AFP(AFP-L3), and des-gammacarboxyprothrombin(DCP). Pre-transplant AFP, AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008. Hazard ratios(HR) for recurrence and death were calculated. Univariate and multivariate regression analyses were conducted. C-statistics were used to compare biomarker-based to predictive models. RESULTS During a median follow-up of 12.2 years, 38 patients recurred and 87 died. The HRs for recurrence in patients with elevated AFP, AFP-L3, and DCP defined by BALAD cut-off values were 2.42(1.18-5.00), 1.86(0.98-3.52), and 2.83(1.42-5.61), respectively. For BALAD, the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91) and 1.59(1.28-1.97). For BALAD-2, the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98) and 1.38(1.09-1.76). For recurrence prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs. 0.64, 0.61, 0.53, and 0.53 for BALAD, BALAD-2, Milan, and UCSF, respectively. Similarly, for death prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61, 0.52, and 0.50 for BALAD, BALAD-2, Milan, and UCSF. A new model combining biomarkers with tumor size at the time of transplant(S-LAD) demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death. CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients, but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD). | Nicha Wongjarupong Gabriela M Negron-Ocasio Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts | 2018 | World Journal of Gastroenterology2018，24，12： | 5 |
| 4 | α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma显示文摘 | Jorge A. Marrero Ziding Feng Yinghui Wang Mindie H. Nguyen Alex S. Befeler Lewis R. Roberts K. Rajender Reddy Denise Harnois Josep M. Llovet Daniel Normolle Jackie Dalhgren David Chia Anna S. Lok Paul D. Wagner Sudhir Srivastava Myron Schwartz | 2009 | Gastroenterology2009，，1： | 3 |
| 5 | Sofosbuvir and Ribavirin for Treatment of Compensated Recurrent Hepatitis C Virus Infection After Liver Transplantation显示文摘 | Michael Charlton Edward Gane Michael P. Manns Robert S. Brown Michael P. Curry Paul Y. Kwo Robert J. Fontana Richard Gilroy Lewis Teperman Andrew J. Muir John G. McHutchison William T. Symonds Diana Brainard Brian Kirby Hadas Dvory-Sobol Jill Denning Sara | 2014 | Gastroenterology2014，，： | 2 |
| 6 | HealthAgents: distributed multi-agent brain tumor diagnosis and?prognosis显示文摘 | Horacio González-Vélez Mariola Mier Margarida Julià-Sapé Theodoros N. Arvanitis Juan M. García-Gómez Montserrat Robles Paul H. Lewis Srinandan Dasmahapatra David Dupplaw Andrew Peet Carles Arús Bernardo Celda Sabine Huffel Magí Lluch-Ariet | 2009 | Applied Intelligence2009，，3： | 1 |
| 7 | The role of ultrasound examination in the first trimester and at 16 weeks’ gestation to predict fetal complications in monochorionic diamniotic twin pregnancies显示文摘 | Liesbeth Lewi Paul Lewi Anke Diemert Jacques Jani Leonardo Gucciardo Tim Van Mieghem Elisa Doné Eduardo Gratacós Agnes Huber Kurt Hecher Jan Deprest | 2008 | American Journal of Obstetrics and Gynecology2008，，5： | 1 |
| 8 | 'The Springs of Motion:Jonathan Edwards on Emotions,Character,and Agency,'显示文摘 | Paul Lewis | | 0，，： | 1 |
| 9 | Signal Transduction through MAP Kinase Cascades显示文摘 | Timothy S. Lewis Paul S. Shapiro Natalie G. Ahn | 1998 | Advances in Cancer Research1998，，： | 1 |
| 10 | field scale design and operation Model simulations in support of of bioremediation based on co- metabolic degradation显示文摘 | Lang M M Paul V R Lewis S | 1997 | Ground Water1997，35，4： | 1 |
| 11 | Heritability of Platelet Responsiveness to Aspirin in Activation Pathways Directly and Indirectly Related to Cyclooxygenase-1显示文摘 | Nauder Faraday Lisa R. Yanek Rasika Mathias J Enrique Herrera-Galeano Dhananjay Vaidya Taryn F. Moy M Daniele Fallin Alexander F. Wilson Paul F. Bray Lewis C. Becker Diane M. Becker | 2007 | Circulation2007，，19： | 1 |
| 12 | Role of Raman spectroscopy and surface enhanced Raman spectroscopy in colorectal cancer显示文摘Colorectal cancer(CRC) is the fourth most commoncancer in the United Kingdom and is the second largest cause of cancer related death in the United Kingdom after lung cancer.Currently in the United Kingdom there is not a diagnostic test that has sufficient differentiation between patients with cancer and those without cancer so the current referral system relies on symptomatic presentation in a primary care setting.Raman spectroscopy and surface enhanced Raman spectroscopy(SERS) are forms of vibrational spectroscopy that offer a nondestructive method to gain molecular information about biological samples.The techniques offer a wide range of applications from in vivo or in vitro diagnostics using endoscopic probes,to the use of micro-spectrometers for analysis of biofluids.The techniques have the potential to detect molecular changes prior to any morphological changes occurring in the tissue and therefore could offer many possibilities to aid the detection of CRC.The purpose of this review is to look at the current state of diagnostic technology in the United Kingdom.The development of Raman spectroscopy and SERS in clinical applications relation for CRC will then be discussed.Finally,future areas of research of Raman/SERS as a clinical tool for the diagnosis of CRC are also discussed. | Cerys A Jenkins Paul D Lewis Peter R Dunstan Dean A Harris | 2016 | World Journal of Gastrointestinal Oncology2016，8，5： | 1 |
| 13 | Patterning self-assembled monolayers显示文摘 | Smith Rachel K Lewis Penelope A Weiss Paul S | 2004 | Prog Surf Sci2004，75，： | 1 |
| 14 | Relation Between Atherosclerosis Risk Factors and Aspirin Resistance in a Primary Prevention Population显示文摘 | Nauder Faraday Diane M. Becker Lisa R. Yanek Jesus Enrique Herrera-Galeano Jodi B. Segal Taryn F. Moy Paul F. Bray Lewis C. Becker | 2006 | The American Journal of Cardiology2006，，6： | 1 |
| 15 | Obesity is linked with lower brain volume in 700 AD and MCI patients显示文摘 | April J. Ho Cyrus A. Raji James T. Becker Oscar L. Lopez Lewis H. Kuller Xue Hua Suh Lee Derrek Hibar Ivo D. Dinov Jason L. Stein Clifford R. Jack Michael W. Weiner Arthur W. Toga Paul M. Thompson | 2010 | Neurobiology of Aging2010，，8： | 1 |
| 16 | Guidelines for the Management of Spontaneous Intracerebral Hemorrhage in Adults. 2007 Update. Guideline From the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outco显示文摘 | Joseph Broderick Sander Connolly Edward Feldmann Daniel Hanley Carlos Kase Derk Krieger Marc Mayberg Lewis Morgenstern Christopher S. Ogilvy Paul Vespa Mario Zuccarello | 2007 | Stroke2007，，6： | 1 |
| 17 | Clinical outcome and placental characteristics of monochorionic diamniotic twin pairs with early- and late-onset discordant growth显示文摘 | Liesbeth Lewi Leonardo Gucciardo Agnes Huber Jacques Jani Tim Van Mieghem Elisa Doné Mieke Cannie Eduardo Gratacós Anke Diemert Kurt Hecher Paul Lewi Jan Deprest | 2008 | American Journal of Obstetrics and Gynecology2008，，5： | 1 |
| 18 | A convenient synthesis of naphthazarin and naphthopurpurin显示文摘 | Lewis J R Paul J | 1977 | Z Naturforsch B:Anorg Chem Org Chem1977，32，12： | 1 |
| 19 | Asthmalike biphasic airway responses in Brown Norway rats sensitized by dermal exposure to dry trimellitic anhydride powder显示文摘 | Xing-Dong Zhang Jeffrey S Fedan Daniel M Lewis Paul D Siegel | 2004 | The Journal of Allergy and Clinical Immunology2004，，2： | 1 |
| 20 | PORTOPULMONARY HYPERTENSION AND THE LIVER TRANSPLANT CANDIDATE显示文摘 | Paul C. Kuo Jeffrey S. Plotkin Sean Gaine Rebecca A. Schroeder Vinod K. Rustgi Lewis J. Rubin Lynt B. Johnson | 1999 | Transplantation1999，，8： | 1 |
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