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142篇 您的检索式:作者名="Paul Wilson"
    题名 作者 年代 出处 被引量
1The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease显示文摘Marno C. Ryan Catherine Itsiopoulos Tania Thodis Glenn Ward Nicholas Trost Sophie Hofferberth Kerin O’Dea Paul V. Desmond Nathan A. Johnson Andrew M. Wilson 2013Journal of Hepatology2013,,1:6
2Energy balance closure at FLUXNET sites显示文摘Kell Wilson Allen Goldstein Eva Falge Marc Aubinet Dennis Baldocchi Paul Berbigier Christian Bernhofer Reinhart Ceulemans Han Dolman Chris Field Achim Grelle Andreas Ibrom B.E Law Andy Kowalski Tilden Meyers John Moncrieff Russ Monson Walter Oechel John T 2002Agricultural and Forest Meteorology2002,,1:4
3Estimation and inference in two-stage, semi-parametric models of production processes显示文摘Léopold Simar Paul W. Wilson 2005Journal of Econometrics2005,,1:3
4Trace analysis of off-flavor/odor compounds in water using liquid-liquid microextraction coupled with gas chromatography--positive chemical ionization-tandem mass spectrometry显示文摘一快速,便宜并且实验室友好方法为 off-flavor/odor 混合物的分析被开发在新鲜并且用有化学电离双人脚踏车团 spectrometry 的煤气的层析的盐水。Off-flavor/odor 混合物包括了 geosmin, 2- methylisoborneol (MIB ) , 2-isobutyl-3-methyoxypyrazine (IBMP ) ,和 2-isopropyl-3-methoxypyrazine (IPMP ) 。用这个方法,一件单个样品能用仅仅器官的溶剂的 1 mL 在分钟以内被提取。为 IPMP, IBMP, MIB,和 geosmin 的离子转变是 153 > 121, 167 > 125, 152 > 95,和 165 > 109 分别地。为分析 MIB 的这个方法的线性从 4 ~ 200 ng 灰潲捡 ? 獩瀠潲潰敳 ? 潴搠獩潣敶 ? 灳瑡潩整灭牯污瀠瑡整湲 ? 景栠畯敳潨摬琠慲敶 ? 牦浯琠敨琠硡 ? 牴橡 ' 啼蟮夀鳜嫪摤徝攥?? 慬杲 ? 畮扭牥漠 ? 潰湩 ?潬慣楴湯Jian LU Paul S. WILLS P. CHRIS WILSON 2016Frontiers of Environmental Science & Engineering2016,10,3:3
5Changes in the colon microbiota and intestinal cytokine gene expression following minimal intestinal surgery显示文摘AIM: To investigate the impact of minor abdominal surgery on the caecal microbial population and on markers of gut inflammation.METHODS: Four week old piglets were randomly allocated to a no-surgery 'control' group(n = 6) or a 'transection surgery' group(n = 5).During the transection surgery procedure, a conventional midline incision of the lower abdominal wall was made and the small intestine was transected at a site 225 cm proximal to the ileocaecal valve, a 2 cm segment was removed and the intestine was re-anastomosed.Piglets received a polymeric infant formula diet throughout the study period and were sacrificed at two weeks post-surgery.Clinical outcomes including weight, stool consistency and presence of stool fat globules were monitored.High throughput DNA sequencing of colonic content was used to detect surgery-relateddisturbances in microbial composition at phylum, family and genus level.Diversity and richness estimates were calculated for the control and minor surgery groups.As disturbances in the gut microbial community are linked to inflammation we compared the gene expression of key inflammatory cytokines(TNF, IL1 B, IL18, IL12, IL8, IL6 and IL10) in ileum, terminal ileum and colon mucosal extracts obtained from control and abdominal surgery groups at two weeks post-surgery.RESULTS: Changes in the relative abundance of bacterial species at family and genus level were confined to bacterial members of the Proteobacteria and Bacteroidetes phyla.Family level compositional shifts included a reduction in the relative abundance of Enterobacteriaceae(22.95 ± 5.27 vs 2.07 ± 0.72, P < 0.01), Bacteroidaceae(2.54 ± 0.56 vs 0.86 ± 0.43, P < 0.05) and Rhodospirillaceae(0.40 ± 0.14 vs 0.00 ± 0.00, P < 0.05) following transection surgery.Similarly, at the genus level, changes associated with transection surgery were restricted to members of the Proteobacteria and Bacteroidetes phyla and included decreased relative abundance of Enterobacteriaceae(29.20 ± 6.74 vs 2.88 ± 1.08, P < 0.01), Alistipes(4.82 ± 1.73 vs 0.18 ± 0.13, P < 0.05) and Thalassospira(0.53 ± 0.19 vs 0.00 ± 0.00, P < 0.05).Surgeryassociated microbial dysbiosis was accompanied by increased gene expression of markers of inflammation.Within the ileum IL6 expression was decreased(4.46 ± 1.60 vs 0.24 ± 0.06, P < 0.05) following transection surgery.In the terminal ileum, gene expression of TNF was decreased(1.51 ± 0.13 vs 0.80 ± 0.16, P < 0.01) and IL18(1.21 ± 0.18 vs 2.13 ± 0.24, P < 0.01), IL12(1.04 ± 0.16 vs 1.82 ± 0.32, P < 0.05) and IL10(1.04 ± 0.06 vs 1.43 ± 0.09, P < 0.01) gene expression increased following transection surgery.Within the colon, IL12(0.72 ± 0.13 vs 1.78 ± 0.28, P < 0.01) and IL10(0.98 ± 0.02 vs 1.95 ± 0.14, P < 0.01) gene expression were increased following transection surgery.CONCLUSION: This study suggests that minor abdominal surgery in infants, results in long-term alteration of the colonic microbial composition and persistent gastrointestinal inflammation.Susan Lapthorne Julie E Bines Fiona Fouhy Nicole L Dellios Guineva Wilson Sarah L Thomas Michelle Scurr Catherine Stanton Paul D Cotter Prue M Pereira-Fantini 2015World Journal of Gastroenterology2015,21,14:3
6Surveillance of patients following surgery with curative intent for colorectal cancer显示文摘Surveillance after resection of colorectal cancer with curative intent is an important component of post- operative care. Clinical review, imaging, colonoscopy, and cost to the community are among significant issues to consider in planning a surveillance regime. This review aims to identify the available evidence for the use of surveillance and its individual components. The literature pertaining to follow-up of patients following potentially curative surgery for colorectal cancer was reviewed in order to formulate a summary of the wide range of clinical practice. There is evidence of improved survival of patients undergoing more intense follow-up compared with those having minimal surveillance, with an estimated overall 5-year gain of up to 10%. The efficacy of individual components of follow-up regimes remains unclear, but an overall package of 'intensive' follow-up including clinical review, liver imaging, and colonoscopy appears to be of benefit. It is cost-effective and can be specialist or community-based.Steven Gan Katherine Wilson Paul Hollington 2007World Journal of Gastroenterology2007,13,28:3
7Activation of Pancreatic Stellate Cells in Human and Experimental Pancreatic Fibrosis显示文摘Paul S. Haber Gregory W. Keogh Minoti V. Apte Corey S. Moran Nancy L. Stewart Darrell H.G. Crawford Romano C. Pirola Geoffrey W. McCaughan Grant A. Ramm Jeremy S. Wilson 1999The American Journal of Pathology1999,,4:2
8Management and Outcome of Permanent Pacemaker and Implantable Cardioverter-Defibrillator Infections显示文摘Muhammad R. Sohail Daniel Z. Uslan Akbar H. Khan Paul A. Friedman David L. Hayes Walter R. Wilson James M. Steckelberg Sarah Stoner Larry M. Baddour 2007Journal of the American College of Cardiology2007,,18:2
9Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically显示文摘Tracy L. Putoczki Stefan Thiem Andrea Loving Rita A. Busuttil Nicholas J. Wilson Paul K. Ziegler Paul Nguyen Adele Preaudet Ryan Farid Kirsten Edwards Yeliz Boglev Rodney B. Luwor Andrew Jarnicki David Horst Alex Boussioutas Joan K. Heath Oliver M. Sieber 2013Cancer Cell2013,,:2
10Structure and evolution of an obliquely sheared continental margin: Rio Muni, West Africa显示文摘Jonathan P. Turner Bruce R. Rosendahl Paul G. Wilson 2003Tectonophysics2003,,1:1
11Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study显示文摘Ronenn Roubenoff Helen Parise Hélène A Payette Leslie W Abad Ralph D’Agostino Paul F Jacques Peter W.F Wilson Charles A Dinarello Tamara B Harris 2003The American Journal of Medicine2003,,6:1
12Potential Value of Contrast-Enhanced Intraoperative Ultrasonography During Partial Hepatectomy for Metastases: An Essential Investigation Before Resection?显示文摘Edward Leen Piercarlo Ceccotti Susan J. Moug Paul Glen John MacQuarrie Wilson J. Angerson Thomas Albrecht Joachim Hohmann Anja Oldenburg Jorg Peter Ritz Paul G. Horgan 2006Annals of Surgery2006,,2:1
13The characteristics of SAPO-34 which influence the conversion of methanol to light olefins 显示文摘Wilson Stephen Barger Paul 1999Micro- porous and Mesoporous Materials1999,29,12:1
14Potential of Total Cycle Time Compression in Construction显示文摘Ralph Barker Paul Childerhouse Mohamed Naim Jan Masat Derek Wilson 2004Journal of Construction Engineering and Management2004,130,2:1
15The Determinants of Trade Credit Demand: Survey Evidence and Empirical Analysis 显示文摘Salima Paul Nick Wilson 2007Joumal of Accounting2007,,12:1
16Heritability of Platelet Responsiveness to Aspirin in Activation Pathways Directly and Indirectly Related to Cyclooxygenase-1显示文摘Nauder Faraday Lisa R. Yanek Rasika Mathias J Enrique Herrera-Galeano Dhananjay Vaidya Taryn F. Moy M Daniele Fallin Alexander F. Wilson Paul F. Bray Lewis C. Becker Diane M. Becker 2007Circulation2007,,19:1
17A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen显示文摘Xiao-Jun Ma Zuncai Wang Paula D Ryan Steven J Isakoff Anne Barmettler Andrew Fuller Beth Muir Gayatry Mohapatra Ranelle Salunga J.Todd Tuggle Yen Tran Diem Tran Ana Tassin Paul Amon Wilson Wang Wei Wang Edward Enright Kimberly Stecker Eden Estepa-Sabal Ba 2004Cancer Cell2004,,6:1
18Activation of Pancreatic Stellate Cells in Human and Experimental Pancreatic Fibrosis显示文摘Paul S. Haber Gregory W. Keogh Minoti V. Apte Corey S. Moran Nancy L. Stewart Darrell H.G. Crawford Romano C. Pirola Geoffrey W. McCaughan Grant A. Ramm Jeremy S. Wilson 1999The American Journal of Pathology1999,,4:1
19The chemistry and behaviour of antimony in the soil environment with comparisons to arsenic: A critical review显示文摘Susan C. Wilson Peter V. Lockwood Paul M. Ashley Matthew Tighe 2009Environmental Pollution2009,,5:1
20From Bail-out to Bail-in显示文摘Paul Calello Wilson Ervin 2001The Economist2001,,1:1
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